Arunabha Bose,Sorab N Dalal
Arunabha Bose
14-3-3ε and 14-3-3γ localize to the centrosome and regulate centrosome duplication, by inhibiting cdc25C function. As 14-3-3γ and 14-3-3ε form a complex with centrosomal proteins, we asked if this ability was required to regulate centro...
PM2.5 affects establishment of immune tolerance in newborn mice by reducing PD-L1 expression [0.03%]
PM2.5通过降低PD-L1的表达影响新生小鼠免疫耐受的建立
L I Yan,Caihui Gong,Linyan Ying et al.
L I Yan et al.
This study was conducted to determine whether exposure to particulate matter 2.5 (PM2.5) affects the immune tolerance of neonatal mice via the regulation of PD-L1 expression. One-week-old BALB/c mice were exposed to PM2.5 for 8 days. From d...
Shengjiang Powder ameliorates myocardial injury in septic rats by downregulating the phosphorylation of P38-MAPK [0.03%]
圣 Jill 粉通过下调 P38-MAPK 磷酸化改善脓毒症大鼠心肌损伤作用机制研究
Yiming Qian,Fenghua Qian,Weiwei Zhang et al.
Yiming Qian et al.
Sepsis is the systemic inflammatory response caused by infection. Cardiac dysfunction is an acknowledged result of sepsis. Shengjiang Powder, a prescribed traditional Chinese medicine, showed anti-infection and antipyretic functions in our ...
ABCG2 aptamer selectively delivers doxorubicin to drug-resistant breast cancer cells [0.03%]
ABCG2核酸适配体选择性地将阿霉素输送到耐药乳腺癌细胞中
Shirin Hashemitabar,Rezvan Yazdian-Robati,Maryam Hashemi et al.
Shirin Hashemitabar et al.
Chemotherapy is the most widely used treatment for cancer therapy, but its efficacy is limited by the side effects of non-specific cytotoxic drugs. Ligand-based targeting drug-delivery system is a solution to circumvent this issue. In this ...
Francesca DI Felice,Gioacchino Micheli,Giorgio Camilloni
Francesca DI Felice
Restriction enzymes have been identified in the early 1950s of the past century and have quickly become key players in the molecular biology of DNA. Forty years ago, the scientists whose pioneering work had explored the activity and sequenc...
Review
Journal of biosciences. 2019 Jun;44(2):38. DOI: 2019
Overexpression of serum exosomal HOTAIR is correlated with poor survival and poor response to chemotherapy in breast cancer patients [0.03%]
血清外泌体HOTAIR高表达与乳腺癌患者预后差及化疗效果不佳相关
Shicong Tang,Kai Zheng,Yiyin Tang et al.
Shicong Tang et al.
To investigate the source of serum exosomal HOTAIR, to uncover the diagnostic and prognostic values of serum exosomal HOTAIR, and to discern the expression of serum exosomal HOTAIR between neoadjuvant chemotherapy and response to tamoxifen ...
Over-expression of Hsp83 in grossly depleted hsrω lncRNA background causes synthetic lethality and l(2)gl phenocopy in Drosophila [0.03%]
Hsp83过表达引起hsrω ncRNA背景显著下降的果蝇中合成致死及l(2)gl表型模拟
Mukulika Ray,Sundaram Acharya,Sakshi Shambhavi et al.
Mukulika Ray et al.
We examined interactions between the 83 kDa heat-shock protein (Hsp83) and hsrω long noncoding RNAs (lncRNAs) in hsrω66 Hsp90GFP homozygotes, which almost completely lack hsrω lncRNAs but over-express Hsp83. All +/+; hsrω66 Hsp90GFP pro...
Macromolecular properties and partial amino acid sequence of a Kunitz-type protease inhibitor from okra (Abelmoschus esculentus) seeds [0.03%]
秋葵籽蛋白酶抑制剂的理化性质及氨基酸序列测定
Debparna Datta,Gottfried Pohlentz,Saradamoni Mondal et al.
Debparna Datta et al.
A Kunitz-type protease inhibitor (OPI, okra protease inhibitor) has been purified from okra (Abelmoschus esculentus) seeds by a combination of ammonium sulfate precipitation, anion-exchange chromatography and reverse-phase high-performance ...
Comparison of Treponema pallidum genomes for the prediction of resistance genes [0.03%]
梅毒螺旋体基因组的比较以预测抗性基因
Ronaldo Omizolo DE Souza,Kesia Esther DA Silva,Rodrigo Matheus Pereira et al.
Ronaldo Omizolo DE Souza et al.
Syphilis is a sexually transmitted infection caused by Treponema pallidum, which is highly prevalent in several countries, including Brazil. The use of bioinformatics' tools for the identification of resistance genes is an important practic...
Comparative Study
Journal of biosciences. 2019 Jun;44(2):34. DOI: 2019
Multifaceted role of keratins in epithelial cell differentiation and transformation [0.03%]
角蛋白在上皮细胞分化及转化中的作用机制研究进展
Crismita Dmello,Saumya S Srivastava,Richa Tiwari et al.
Crismita Dmello et al.
Keratins, the epithelial-predominant members of the intermediate filament superfamily, are expressed in a pairwise, tissuespecific and differentiation-dependent manner. There are 28 type I and 26 type II keratins, which share a common struc...
Review
Journal of biosciences. 2019 Jun;44(2):33. DOI: 2019