Computational identification of perturbed pathways in type 2 diabetes mellitus patients reveals necroptosis and NF-κB pathways with potential for susceptibility to psoriasis [0.03%]
计算鉴定2型糖尿病患者紊乱的信号通路发现坏死性凋亡和NF-κB通路易患银屑病
Rohit Kumar,Surabhi Seth,Anasuya Bhargav et al.
Rohit Kumar et al.
Psoriasis (PS) is one of the comorbidities of type 2 diabetes mellitus (T2DM). The molecular processes leading to the T2DM-PS comorbidity are not fully understood. Recently, six genes (IL23R, IL12B, IL23A, GSK3B, PTPN1, and STX4) were ident...
Life history traits and spatial characteristics of an Asia Minor thin-toed gecko population (Mediodactylus heterocercus Blanford, 1874) [0.03%]
小趾壁虎(Mediodactylusheterocercus)种群的生活史特征及空间分布属性
Cantekin Dursun,Kamil Candan,Elif YıLDıRıM Caynak et al.
Cantekin Dursun et al.
The aim of the present study was to obtain information on certain life history traits such as life span and age of sexual maturity of individuals of the species Mediodactylus heterocercus using the method of skeletochronology. A total of 31...
Localization of mitochondria along axons and at synapses in C. elegans touch receptor neurons is necessary for touch habituation [0.03%]
线粒体在线虫触觉神经元轴突及突触上的定位对于适应外界触觉刺激是必需的
Sneha Hegde,Nayantara Varma,Parul Sood et al.
Sneha Hegde et al.
Neuronal mitochondria are important for neuronal survival and function. Mitochondria buffer calcium, produce ATP, and contribute to reactive oxygen species (ROS) homeostasis, processes that help in neuronal outgrowth and synaptic transmissi...
Modulation of the biphasic pattern of cortical reorganization in spinal cord-transected rats by external magnetic fields [0.03%]
外磁场对脊髓切断大鼠皮层重组双相规律的调控作用
Sajeev Kaur,Suman Jain,Ritika Bhardwaj et al.
Sajeev Kaur et al.
A biphasic pattern of reorganization in the somatosensory cortical area, representing the hindlimb or forelimb, has been shown after complete spinal cord injury (cSCI) in rats. The present study hypothesized that extremely low-frequency mag...
Swati Ghosh,Divya Vishnu,Shravani Pillanjinayya et al.
Swati Ghosh et al.
Life on Earth is viable within a narrow window of physical parameters such as temperature, atmospheric pressure, oxygen concentration, etc. Fortunately, all these parameters are within that life-permissive window in most parts of our planet...
Akash DAS,Drishtee Barua,Souvik Pal et al.
Akash DAS et al.
Plants, being sessile organisms, are continually exposed to diverse combinations of biotic and abiotic stresses in their natural habitats. Combined stresses are considered significant threats to plants, particularly in the context of today'...
Role of the extracellular matrix in amylin aggregation: Opportunities for improved therapy in type 2 diabetes mellitus [0.03%]
细胞外基质在胰多肽聚集中的作用及在2型糖尿病治疗中的应用机遇
Sagarika Prabhakar,Priyadarshini Veerabhadraswamy,Nikhil R Gandasi
Sagarika Prabhakar
In most individuals with type 2 diabetes mellitus (T2DM), aggregation of amylin or islet amyloid polypeptide (IAPP) leads to β-cell apoptosis, impairs glucose-stimulated insulin secretion, and causes islet disorganisation (Cooper et al. 19...
Review
Journal of biosciences. 2025:50:68. DOI: 2025
Bite size of Caenorhabditis elegans regulates feeding, satiety and development on a diet of live yeast [0.03%]
秀丽隐杆线虫的咬食大小调节其在酵母饮食下的进食、饱腹感和发育情况
Atreyee DE,Amit K Sahu,Varsha K Singh
Atreyee DE
In the wild, the nematode Caenorhabditis elegans primarily feeds on microbes, which are abundant in rotting vegetation. Studies show that several gram-positive and gram-negative bacterial populations predominantly constitute the C. elegans ...
An RFamide signaling system balances turning and forward locomotion to optimize global food search in Caenorhabditis elegans [0.03%]
一种射频amide信号系统平衡了转向和前进运动以优化模式生物秀丽隐杆线虫的全局觅食行为
Anirrban Ghosh,Navneet Shahi,Raja Bhattacharya
Anirrban Ghosh
Neuromodulators such as neuropeptides activate specific G-protein-coupled receptors to reconfigure activity patterns of neural circuits and alter animal behavior. However, we have an incomplete understanding of the context-dependent mechani...
Thirty years of the Baranyi and Roberts model: Predictions, precautions, risk assessment, and beyond [0.03%]
巴拉尼和罗伯茨模型的三十年：预测、预防、风险评估及展望
Dhruba Dey,Debapriya Mukherjee,Pallab Ghosh et al.
Dhruba Dey et al.
In today's world, food safety is of paramount importance. Even a slight lapse can lead to significant economic losses and place a heavy burden on the healthcare system. Over the years, multiple mathematical models have been developed to pre...
Review
Journal of biosciences. 2025:50:65. DOI: 2025