Optimal endogenous controls for microRNA analysis of visceral adipose tissue in the NAFLD mouse model [0.03%]
NAFLD小鼠模型中内脏脂肪组织microRNA分析的最佳内源性对照
Veronika Uhrova,Helena Parova,Zuzana Cervinkova et al.
Veronika Uhrova et al.
The selection of proper reference genes and materials is critical in the design of PCR experiments, especially for differential expression studies. In this study, we propose a method to identify robust endogenous control miRNAs in the visce...
Role of EhLINE1_ORF1p outside retrotransposition: Downregulation causes growth defects in Entamoeba histolytica [0.03%]
除逆转录转座作用外EhLINE1_ORF1p的作用:Entamoeba histolytica中该基因表达下调导致生长缺陷
Devinder Kaur,Shashi Shekhar Singh,Shraddha Sharma et al.
Devinder Kaur et al.
The constitutive expression of EhLINE1_ORF1p in Entamoeba histolytica cells in the absence of retrotransposition suggests that this protein may serve roles beyond retrotransposition. To delve into this possibility, we generated and analyzed...
Prenatal protein deficiency causes age-specific alteration in number and distribution of inhibitory neurons in the somatosensory cortex during early postnatal development [0.03%]
孕期蛋白缺乏引起感觉皮层抑制性神经元的年龄特异性变化
Arti Kumari,V Rema,Neeraj Jain
Arti Kumari
Prenatal protein deficiency causes behavioral and cognitive dysfunctions in children. The deficits could be caused by altered acquisition and processing of sensory information in the brain. Although GABAergic neurons are the key regulators ...
Contrasting sequence polymorphism and structural basis patterns of Plasmodium falciparum histidine-rich proteins 2/3 in Cameroon and India [0.03%]
喀麦隆和印度疟原虫血红素富集蛋白2/3的序列多态性及结构基础模式对比分析
Loick Pradel Kojom Foko,Joseph Hawadak,Soumyananda Chakraborti et al.
Loick Pradel Kojom Foko et al.
The bulk of malaria rapid diagnostic tests (RDTs) target Plasmodium falciparum histidine-rich protein 2 (PfHRP2), but several reports have shown that sequence variations in this protein are associated with falsenegative RDT results. The pol...
Analysis of downstream targets of PAX6 and LHX2, fundamental regulators of the developing mammalian neocortex [0.03%]
PAX6和LHX2的下游靶点分析：发育哺乳动物新皮质的基本调节因子
Mansi Srivastava,Varun Suresh,Shubha Tole
Mansi Srivastava
The transcription factors PAX6 and LHX2 play fundamental roles in mammalian cerebral cortical development. Loss of either factor causes depletion of the cortical progenitor pool and reduction of neurogenesis of later-born cortical neurons. ...
Glutamate metabolism disruption in Johanson-Blizzard syndrome: Insights from C. elegans ubr-1 model [0.03%]
Johanson-Blizzard综合征中的谷氨酸代谢紊乱：来自秀丽隐杆线虫ubr-1模型的见解
Yi Li,Shangbang Gao
Yi Li
The Johanson-Blizzard syndrome (JBS) is a complex autosomal recessive disorder that manifests through a spectrum of symptoms, with deficiencies in the ubiquitin-protein ligase E3 component N-recognin 1 (UBR-1) at its genetic core. Despite i...
Review
Journal of biosciences. 2025:50:5. DOI: 2025
Sensory modulation of neuropeptide signaling by CASY-1 gates cholinergic transmission at Caenorhabditis elegans neuromuscular junction [0.03%]
CASY-1调节神经肽信号传导以门控Caenorhabditis elegans神经肌突触的胆碱能传递
Navneet Shahi,Shruti Thapliyal,Kavita Babu
Navneet Shahi
The neuromuscular junction (NMJ) is crucial for understanding the fundamentals of synaptic transmission and activity. Various modulators operate within neuronal circuits, from sensory to motor neurons, to influence synaptic transmission at ...
Anica Dadwal,Shilpa Sharma,Shailendra Asthana et al.
Anica Dadwal et al.
Initiation of protein translation is one of the key steps in protein synthesis carried out by translation initiation factors in conjunction with ribosomes. The roles and mechanisms of these initiation factors in prokaryotic and eukaryotic p...
From data to discovery: Neuroinformatics in understanding Alzheimer's disease [0.03%]
从数据到发现：神经信息学在理解阿尔茨海默病方面的应用
Sonu Pahal,Vishvender Pahal,Amit Chaudhary
Sonu Pahal
Neuroinformatics, an interdisciplinary field integrating neuroscience and informatics, plays a crucial role in understanding the complexities of the brain and neurological diseases such as Alzheimer's disease (AD). This review explores the ...
Review
Journal of biosciences. 2025:50:2. DOI: 2025
Memory defects in post-dauer Caenorhabditis elegans are a result of altered insulin signalling [0.03%]
dafer缺陷导致的秀丽隐杆线虫记忆缺失是由胰岛素信号通路改变引起的
Rasitha Santhosh Kanakalatha,Anoopkumar Thekkuveettil
Rasitha Santhosh Kanakalatha
In response to unfavourable conditions and environmental duress, Caenorhabditis elegans follows an alternative developmental stage called the dauer larva, which is associated with various metabolic changes. Dauers can survive in harsh condi...