Pan-cancer analysis of cancer-specific transcript isoforms reveals the regulatory impact of isoform switching on the alteration of the interplay between RBPs and miRNAs in cancers [0.03%]
泛癌分析癌症特异性转录本异构体揭示异构体转换对癌症中RBPs和miRNA之间相互作用改变的调控影响
Sukhen DAS Mandal,Sumit Mukherjee
Sukhen DAS Mandal
The switch in the predominantly expressed transcript isoform of the same gene has been identified as a significant factor in the progression of various types of cancer. These switches can impact the gain or loss of different 3'UTRs, which a...
Evolution of body size and selfhood: Size-scaling from selfless reproduction to enhanced self-preservation [0.03%]
身体大小和自我意识的进化:从无私繁殖到增强自我保护的规模调整规律
Douglas S Glazier
Douglas S Glazier
Our knowledge of how and why various biological and ecological traits relate (scale) to body size has grown at a rapid pace. In this exploratory analysis, I aim to further advance our knowledge of biological scaling by arguing that individu...
Review
Journal of biosciences. 2025:50:30. DOI: 2025
What keeps Caenorhabditis elegans precise: The spatiotemporal regulation of defecation [0.03%]
调控秀丽隐杆线虫精确排泄的时空机制研究
Qiang Liu,Louis Tao
Qiang Liu
Rhythmic behaviors controlled by internal biological clocks are universal among living organisms, ranging from single cells to humans. The inner workings and modulations of the intrinsic oscillatory activities that underlie these rhythmic b...
Review
Journal of biosciences. 2025:50:29. DOI: 2025
A jack of all trades: Hermaphrodite-specific serotonergic neuron in C. elegans [0.03%]
多重身份的调节者:秀丽隐杆线虫的雄性特异性血清素能神经元
Patrick Laurent
Patrick Laurent
How does a single neuron type shape both short- and long-term behavior? A study reveals how co-transmission by two hermaphrodite-specific neurons (HSNs) of Caenorhabditis elegans produces both transient and long-lasting effects on its egg-l...
Identifying trials run in India, registered with ClinicalTrials.gov, is not straightforward [0.03%]
在ClinicalTrials.gov网站上识别在美国境外开展的临床试验——以印度为例
Anwesha Dhal Samanta,Jaishree Mendiratta,Gayatri Saberwal
Anwesha Dhal Samanta
Clinical trial registries are invaluable resources for many stakeholders. However, these registries often require customized methodologies to identify studies of interest. To determine what steps it would take to catalog every trial that ha...
Why does community ecology need chemistry? Because keystone molecules can govern food webs [0.03%]
为什么群落生态学需要化学?因为关键分子可以调控食物网
Renee M Borges
Renee M Borges
In an earlier editorial (Borges 2022), I had talked about the keystone concept formulated by Robert Paine. This important concept (Paine 1966) emphasised the idea that biodiversity is maintained by a top-down process in which the removal of...
Dipankar Nandi,Nikita S Ramteke
Dipankar Nandi
The immune system is our defence network and primarily geared to protect us from pathogens and tumors. This aspect is evident in people who lack or possess a compromised immune system and are, therefore, highly susceptible to infections and...
Review
Journal of biosciences. 2025:50:25. DOI: 2025
Independent control of functional rewiring after axon injury by let-7 miRNA and insulin/insulin-like growth factor signaling pathways [0.03%]
胰岛素和let-7通路独立调控神经损伤修复过程中的突触重建
Sruthy Ravivarma,Sibaram Behera,Dipanjan Roy et al.
Sruthy Ravivarma et al.
The capability of neurons to regenerate after injury becomes poor in adulthood. Previous studies indicated that loss of either let-7 miRNA or components of insulin/insulin-like growth factor signaling (IIS) can overcome age-related decline ...
Exploring mitochondrial dynamics and localization under cellular stress: A comprehensive insight [0.03%]
探讨细胞应激下的线粒体动力学和定位:全面透视
Saloni Agarwal,Kavikumar Angamuthu Karuppusamy,Abhishek K Gupta
Saloni Agarwal
Within a cell, the mitochondrion serves various functions, including ATP synthesis, generation of reactive oxygen species, maintenance of iron and calcium ion homeostasis, and apoptosis, all of which are essential for the cell's function. R...
Review
Journal of biosciences. 2025:50:23. DOI: 2025
Fatty acid composition, oil yield, and oil content of sunflower (Helianthus annuus L.) across different pollination treatments [0.03%]
不同授粉处理对向日葵(Helianthus annuus L.)脂肪酸组成、出油率和含油量的影响
Kasim Roba Jilo,Mohammed Abu Edeo,Tedale Alemu Hunde et al.
Kasim Roba Jilo et al.
Sunflower oil, widely used in daily human nutrition and in various industrial applications, is economically important. Sunflower seeds are a rich source of healthy unsaturated fats. Fatty acid composition, particularly the ratio of unsatura...