Yoichi Hiraki,Yasuhiro Tsuji,Naoko Yasumori et al.
Yoichi Hiraki et al.
Objective: This study investigated endogenous factors that may increase the elimination of vancomycin (VCM) in adult methicillin-resistant Staphylococcus aureus (MRSA) patients with pneumonia. ...
Amir Feily,Sima Rasaii,Mohammad Ali Nilforoushzadeh
Amir Feily
Efficient strategy for obtaining reliable pharmacokinetic parameters in population compartmental approaches [0.03%]
群体隔室法中获得可靠药动学参数的高效策略
Junhee Lee,Dongwoo Kang,Euitae Kim et al.
Junhee Lee et al.
Objective: This study aimed to suggest efficient strategies for obtaining reliable pharmacokinetic (PK) parameters in population compartmental approach (PCA) a early-phase or resource-limited clinical trials with limited ...
Antipsychotic polypharmacy and quality of life in patients with schizophrenia treated in primary care in China [0.03%]
中国社区精神分裂症患者抗精神病药联合使用对其生活质量的影响
Cai-Lan Hou,Xin-Rong Ma,Yu Zang et al.
Cai-Lan Hou et al.
Objective: In China, maintenance treatment for clinically stable patients with schizophrenia is usually provided by primary care physicians, but their prescribing patterns have not been studied. This study examined the fr...
Treatment of a patient with severe hemorrhagic fever accompanied by infection with methicillinresistant Staphylococcus aureus, Acinetobacter baumannii, aspergillus and mucor: a case report [0.03%]
一例并发耐甲氧西林金黄色葡萄球菌、鲍曼不动杆菌、曲霉及毛霉感染的重症出血热患者的治疗：病例报告
Di Zhang,Xue Wang,Jing Lv et al.
Di Zhang et al.
A 40-year-old Korean man developed hemorrhagic fever in Xi'an, which is one of the main endemic areas for this illness in China. According to the local epidemiological situation, his condition could have been due to hantavirus infection, bu...
Natalie Hermann,Katja Dressen,Lars Schroeder et al.
Natalie Hermann et al.
Gene regulatory biomarker identification for skin toxicities induced by EGFR inhibitor treatment [0.03%]
EGFR抑制剂治疗引起的皮肤毒性的基因调控生物标志物识别
Vivien Hichert,Michael Steffens,Tanusree Paul et al.
Vivien Hichert et al.
1 Federal Institute for Drugs and Medical Devices (BfArM), Research Division, Bonn, 2 Institute of Pharmacology of Natural Products and Clinical Pharmacology, 3 Department of Internal Medicine II, University of Ulm, Ulm, 4 Pneumology, Thora...
GRP78 knockdown does not affect cytotoxicity of cisplatin in ovarian cancer cells [0.03%]
GRP78敲低不影响顺铂对卵巢癌细胞的细胞毒作用
Maximilian Kullmann,Sandra Kotz,Malte Hellwig et al.
Maximilian Kullmann et al.
A randomized, placebo-controlled repeat-dose thorough QT study of inhaled loxapine in healthy volunteers [0.03%]
利醅普林健康志愿者重复给药彻底QT研究的随机、双盲、安慰剂对照试验
James V Cassella,Daniel A Spyker,Paul P Yeung
James V Cassella
Objective: This randomized, double-blind, active- and placebo-controlled, crossover, thorough QT study assessed the effect of two inhaled loxapine doses on cardiac repolarization as measured by corrected QT (QTc) interval...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2015 Nov;53(11):963-71. DOI:10.5414/CP202457 2015
Characterization of the relationship between dose and blood eosinophil response following subcutaneous administration of mepolizumab [0.03%]
美泊利单抗皮下给药后剂量与血液嗜酸性粒细胞反应之间的关系的特征描述
Isabelle J Pouliquen,Oliver Kornmann,Sharon V Barton et al.
Isabelle J Pouliquen et al.
Objective: Mepolizumab is a humanized IgG1 monoclonal antibody that blocks human IL-5 from binding to the IL-5 receptor, which is mainly expressed on eosinophils. Eosinophils are key cells in the inflammatory cascade of v...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2015 Dec;53(12):1015-27. DOI:10.5414/CP202446 2015