Methotrexate and folic acid supplementation in rheumatoid arthritis: A Japanese claims database and 538,985 patients from April 2015 to November 2020 [0.03%]
日本claims数据库在2015年4月至2020年11月期间纳入的538,985名类风湿关节炎患者使用甲氨蝶呤和叶酸补充剂的情况
Kasumi Takabatake,Mayuko Takeda,Mutsumi Nakamura et al.
Kasumi Takabatake et al.
Objectives: To assess the use of laboratory monitoring, folic acid supplementation, and folinate calcium therapy in patients with rheumatoid arthritis (RA) receiving first-line methotrexate (MTX) according to the 2019 Jap...
Cardiac arrest in an adolescent following an overdose of antidepressants comprising sertraline, quetiapine fumarate, and lamotrigine: Case report [0.03%]
一例合并使用盐酸舍曲林、富马酸喹硫平和拉莫三嗪过量后的青少年心脏骤停病例报告
Li Zheng,Liaoyun Zhang,Fei Wang et al.
Li Zheng et al.
Antidepressant overdose is a prevalent method of self-harm in patients with depression including bipolar disorder. According to the published literature, typical adverse effects are seizures, prolonged QT intervals, and arrhythmias, with ca...
Recombinant human growth hormone in pediatric patients using the FAERS database: Safety profile and update for the period 2004 - 2024 [0.03%]
2004-2024年利用FAERS数据库分析重组人生长激素儿科患者的安全性特点及更新
Lidan Tu,Huafeng Jiang,Jianming Liu et al.
Lidan Tu et al.
Objective: To investigate safety signals associated with recombinant human growth hormone (rhGH) using the FDA Adverse Event Reporting System (FAERS) and make recommendations for its application. ...
Barrington G Woodcock-Kloberdanz
Barrington G Woodcock-Kloberdanz
Novel intravenous human IVIG in patients with secondary immunodeficiency: Interim analysis of a multicenter, prospective, non-interventional study [0.03%]
人源IVIG产品治疗二级免疫缺陷患者的疗效及安全性研究——多中心、前瞻性非干预性研究的中期分析结果
Artur Bauhofer,Silke Aigner,Stephan Borte
Artur Bauhofer
Objective: To evaluate the effectiveness, safety, and tolerability of Yimmug, a novel, highly purified, 10% human plasma-based intravenous immunoglobulin (IVIG) preparation, in patients with secondary immunodeficiency (SI...
Network meta-analysis of bisphosphonates in the treatment of bone metastases from breast cancer [0.03%]
双膦酸盐治疗乳腺癌骨转移的网状Meta分析研究
Li-Wen Zhang,An Huang,Hong-Fang Ma et al.
Li-Wen Zhang et al.
Objective: Through a network meta-analysis, this study aimed to systematically evaluate the efficacy and safety of bisphosphonates in reducing skeletal-related events in patients with bone metastases from breast cancer, p...
Pharmacokinetic and bioequivalence study of apremilast tablets in healthy Chinese subjects under fasting and fed conditions [0.03%]
健康受试者空腹及餐后条件下阿普拉米司片的药代动力学和生物等效性研究
Pan Lu,Fang Yao,Jie Wang et al.
Pan Lu et al.
Apremilast is a pioneering oral selective phosphodiesterase-4 inhibitor for the treatment of psoriasis. To evaluate and compare the pharmacokinetic properties and bioavailability of apremilast tablets manufactured by Nanjing Haijing Pharmac...
Pirfenidone and nintedanib in fibrosing interstitial lung disease: A retrospective study based on a regional university hospital data registry and literature review [0.03%]
基于地区大学医院数据库及文献回顾看肺纤维化间质性肺病的两种药物Pirfenidon和Nintedanib
Carla Sans-Pola,Ricardo Boy,Ana Villar et al.
Carla Sans-Pola et al.
Aims: To evaluate the effectiveness and tolerability of pirfenidone and nintedanib in idiopathic pulmonary fibrosis (IPF) and other fibrotic lung diseases. ...
Prolonged cholinergic toxidrome with markedly low cholinesterase activity after exposure to emamectin benzoate emulsion: A case report [0.03%]
暴露于阿维菌素苯甲酸盐乳剂后的重度胆碱酯酶活性降低和长时间胆碱能中毒表现：病例报告
Hideo Chubachi,Noritaka Kitazume,Kenji Momo et al.
Hideo Chubachi et al.
Emamectin benzoate emulsion is a macrocyclic lactone insecticide that is not classified as an organophosphate or carbamate. We report the case of a man in his 80s with chronic kidney disease and cardiovascular comorbidities who ingested ema...
Pharmacokinetic evaluation of two oral formulations of chlorpromazine in healthy subjects [0.03%]
氯丙嗪两种口服制剂在健康志愿者中的药代动力学评价
Hyo-Jin Min,Jun Gi Hwang,Young-Sim Choi et al.
Hyo-Jin Min et al.
Chlorpromazine is a first-generation antipsychotic agent that exerts its therapeutic effects primarily by antagonizing dopamine D2 receptors. This randomized, open-label, single-dose, two-period, two-sequence crossover study was conducted t...