Evolocumab, a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, is effective and safe in the treatment of hyperlipidemia in chronic kidney disease stage 3 - 4 [0.03%]
Hongxu Zhu,Yufeng Chang,Qi Jin
Hongxu Zhu
Aims: To evaluate the efficacy and safety of evolocumab, a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, in chronic kidney disease (CKD). ...
Fondaparinux to treat cerebral venous sinus thrombosis complicated by heparin-induced thrombocytopenia during puerperium: A case report and literature review [0.03%]
Meng Qi,Xuebing Feng,Lidan Jiang et al.
Meng Qi et al.
Background: Cerebral venous sinus thrombosis (CVST) occurring during the puerperium is a rare yet life-threatening condition. The management of CVST becomes more complex when complicated by heparin-induced thrombocytopeni...
Timing of antimicrobial stewardship intervention and mortality among patients admitted to intensive care unit [0.03%]
Akitoshi Takuma,Airi Miura,Kotono Tagami et al.
Akitoshi Takuma et al.
Objectives: Antimicrobial stewardship is important in the intensive care unit (ICU), where critically ill patients are managed. Herein, we aimed to evaluate the associations between the timing of antimicrobial stewardship...
Dulaglutide-associated body odor with dechallenge and rechallenge in a patient with type 2 diabetes [0.03%]
利拉鲁肽引起的一例2型糖尿病患者的撤药和再用药的体臭反应
Srecko Marusic,Matea Staresinic,Maja Cigrovski Berkovic
Srecko Marusic
Objective: Although uncommon, medications may induce unpleasant body odor, potentially leading to psychosocial distress and reduced treatment adherence. To date, unpleasant body odor has not been recognized as an adverse ...
Pharmocracy via MCC to de-prescribing: The attempted ascent and descent of Everest [0.03%]
从MCC到减药：通向良好药物管理的艰难之路
Barrington G Woodcock-Kloberdanz
Barrington G Woodcock-Kloberdanz
Gastrointestinal symptoms in Parkinson's disease treated in a controlled trial using traditional Chinese medicine (Jia-Wei-Ji-Chuan-Jian decoction) with network pharmacology analysis of active agents and mechanism of action [0.03%]
基于网络药理学分析的中药复方治疗帕金森病胃肠症状的活性成分及作用机制研究
Shi Kay Loong,Feifei Wu,Yizhou Liu et al.
Shi Kay Loong et al.
Background: Gastrointestinal symptoms in Parkinson's disease (PD), in particular chronic constipation, are common and are treated in China using the traditional Chinese medicine (Jia-Wei-Ji-Chuan-Jian decoction) (JWJCJ))....
Polypharmacy and hyperpolypharmacy in elderly (≥ 65 years) pacemaker recipients: Prevalence and association with frailty, physical activity, adherence, and healthcare utilization in a prospective single-center study [0.03%]
基于单中心前瞻性研究的老年人(≥65岁)起搏器植入受者的多重用药和过度多重用药：与衰弱、身体活动、依从性和医疗保健利用的相关性
Miguel Costa,Natália António,Carolina Félix et al.
Miguel Costa et al.
Objectives: To quantify polypharmacy (≥ 5 drugs) and hyperpolypharmacy (≥ 10 drugs) in pacemaker recipients aged ≥ 65 years and to assess associations with frailty (FRAIL), physical activity (IPAQ), medication adherenc...
Inflammatory cytokines, autoantibodies and salivary gland function in Sjögren's syndrome: Effects of T. wilfordii as Hook F medical wine and Tripterygium glycosides tablets [0.03%]
干燥综合征患者炎症细胞因子、自身抗体与唾液腺功能及雷公藤制剂疗效研究
Xiaofu Yu,Pan Chu,Chengcheng Yu et al.
Xiaofu Yu et al.
Objective: This study was conceived to compare the clinical efficacy of Tripterygium wilfordii Hook F (TWHF) medical wine and Tripterygium glycoside tablets (TGTs) in patients with primary Sjögren's syndrome (pSS), mainl...
Prospects for solving difficulties in steroid withdrawal and management supplementing tranilast and roxithromycin in corticosteroid-dependent atopic dermatitis [0.03%]
辅以丙酯洛和曲安奈德治疗依赖性皮质类固醇患者前景展望及管理补充措施
Yasuhiro Horiuchi
Yasuhiro Horiuchi
Intractable cases of atopic dermatitis often exhibit recurrent exacerbations, with the primary treatment being topical steroids. However, prolonged use of steroids can lead to steroid addiction or iatrogenic disease. Withdrawal from steroid...
Prediction of paclitaxel-induced myelosuppression: Validation of a regression model using creatinine clearance and other risk factors obtained retrospectively in hospitalized cancer patients [0.03%]
基于肌酐清除率和其他危险因素的顺铂诱导性髓系毒性预测模型的验证
Yang Hai,Yulong Liu
Yang Hai
Objective: To develop a predictive model for paclitaxel (PTX)-induced moderate-to-severe myelosuppression in hospitalized cancer patients and to evaluate its accuracy through cross-validation. ...