Pharmacokinetics and tolerability of febuxostat after oral administration in healthy Chinese volunteers: a randomized, open-label, singleand multiple-dose three-way crossover study [0.03%]
口服非布司他在健康中国受试者中的药代动力学和耐受性：一项随机、开放标签、单次给药和多次给药三周期交叉试验
Huili Zhou,Yunliang Zheng,Guolan Wu et al.
Huili Zhou et al.
Objective: Febuxostat is a novel non-purine selective inhibitor of xanthine oxidase indicated for the chronic management of hyperuricemia in patients with gout. The aim of the present study was to evaluate the pharmacokin...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2016 Feb;54(2):115-24. DOI:10.5414/CP202394 2016
Hemocoagulase agkistrodon-induced anaphylactic shock: A case report and literature review [0.03%]
银环蛇血凝酶致过敏性休克1例及相关文献复习
Yan-Yan Xu,Xu-Hui Ma,Shao-Jun Zhang
Yan-Yan Xu
Hemocoagulase agkistrodon for injection is the national first-class new drug of China with good hemostatic function and safety for capillary hemorrhage in abdominal incision of surgical patients. Adverse drug reactions (ADRs) to hemocoagula...
Large doses of uterotonic drugs caused type II second degree sinoatrial block during cesarean section [0.03%]
大剂量缩宫药物诱发剖宫产术中心房窦性二度Ⅱ型阻滞１例报告
Zhe-Feng Quan,Ming Tian,Ping Chi
Zhe-Feng Quan
In China, it is a routine procedure to inject 250 μg of hemabate (sterile solution, an oxytocic, contains the tromethamine salt of the (I5S)-15 methyl analogue of naturally occurring prostaglandin F2α in a solution suitable for intramuscu...
The use of unboosted darunavir in the setting of ritonavir intolerance: three case reports [0.03%]
克力芝不耐受情况下使用非增强达芦那韦治疗：3例个案报告
Katelyn Smith,Denese Gomes,Daniel Nixon et al.
Katelyn Smith et al.
Objective: To describe three patients with human immunodeficiency virus (HIV) who were successfully managed with unboosted darunavir (uDRV). Case summarie...
Effects of a novel finasteride 0.25% topical solution on scalp and serum dihydrotestosterone in healthy men with androgenetic alopecia [0.03%]
一种新型的finasteride（非那雄胺）0.25％外用溶液对雄激素性脱发受试者头皮和血清中二氢睾酮的影响：一项概念验证研究
Maurizio Caserini,Milko Radicioni,Chiara Leuratti et al.
Maurizio Caserini et al.
Objective: The effects on scalp and serum dihydrotestosterone (DHT) of different doses of a novel topical solution of 0.25% finasteride (P-3074), a type 2 5α-reductase, were investigated in men with androgenetic alopecia...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2016 Jan;54(1):19-27. DOI:10.5414/CP202467 2016
Yi-Chun Chiang,Yu-Hsuan Yen,Wei-Chiao Chang et al.
Yi-Chun Chiang et al.
Objectives: To investigate the association between rheumatoid arthritis (RA) and urbanization and compare the medication selection for RA patients in urban vs. rural areas. ...
Ifosfamide and etoposide chemotherapy may interact with warfarin, enhancing the warfarin induced anticoagulant response [0.03%]
如果沙斐茂与依托泊苷化疗可能与华法林产生相互作用，增强华法林导致的抗凝血反应
Naoto Okada,Hiroyoshi Watanabe,Shoji Kagami et al.
Naoto Okada et al.
Purpose: To report a case of warfarin-response enhancement during administration of ifosfamide and etoposide chemotherapy. Case summary: ...
Ulrich Jaehde,Gerd Bendas,Daniel Sehrt et al.
Ulrich Jaehde et al.
Bioequivalence study of an extemporaneously prepared oral solution of amlodipine suitable for use in pediatric patients compared to commercial tablets [0.03%]
氨氯地平自制口服液体制剂与市售片剂生物等效性研究用于儿科患者
Anna C van der Vossen,Iris van der Velde,Anton H van den Meiracker et al.
Anna C van der Vossen et al.
Objective: Amlodipine, a long-acting dihydropyridine calcium channel blocker, is frequently prescribed to pediatric patients. To date, no suitable pediatric formulation has been available. In this study, an amlodipine ora...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2016 Jan;54(1):65-72. DOI:10.5414/CP202449 2016
Katja Dressen,Natalie Hermann,Steffen Manekeller et al.
Katja Dressen et al.