Prevalence and type of antidepressant therapy used by German general practitioners to treat female patients with osteoporosis [0.03%]
德国全科医生用于治疗骨质疏松症女性患者的抗抑郁药的使用率和类型
Julia Drosselmeyer,Michael A Rapp,Karel Kostev
Julia Drosselmeyer
Objective: To estimate the prevalence and type of antidepressant medication prescribed by German primary care physicians for patients with depression and osteoporosis. ...
Steady-state bioequivalence 2-way crossover study of two quetiapine prolonged-release 400 mg tablet formulations in normal male and female healthy subjects under fasting conditions [0.03%]
健康受试者空腹条件下两种富马酸奎硫平缓释片(400mg)制剂的生物等效性双交叉序列试验研究
Fethi Trabelsi,Negar Gharavi,Magdalene Kalovidouris et al.
Fethi Trabelsi et al.
Objective: The purpose of this study was to assess bioequivalence between a generic and a brand quetiapine 400 mg prolonged-release (PR) formulation (Pharmathen S.A.; AstraZeneca Seroquel Prolong®τ, Cmax, and Cmin. ANOV...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2016 Sep;54(9):732-42. DOI:10.5414/CP202609 2016
DRESS syndrome and acute generalized exanthematous pustulosis induced by antituberculosis medications and moxifloxacin: case report [0.03%]
抗结核药物及莫西沙星诱导的DRESS综合征和急性泛发性发疹性脓疱病：病例报告
Hyunah Kim,Eun Sook Bang,Seung-Kwan Lim et al.
Hyunah Kim et al.
Objective: To report a rare case of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome caused by antituberculosis (TB) drugs, which progressed to acute generalized exanthematous pustulosis (AGEP) after...
Pharmacokinetics, safety, and tolerability of siponimod (BAF312) in subjects with different levels of hepatic impairment: a single-dose, open-label, parallel-group study [0.03%]
评估siponimod（BAF312）在不同程度肝功能损害患者中的药代动力学、安全性和耐受性的单次给药、开放标签、平行组研究
Kasra Shakeri-Nejad,Vassilios Aslanis,Uday Kiran Veldandi et al.
Kasra Shakeri-Nejad et al.
Objective: To assess the pharmacokinetics (PK), safety, and tolerability of siponimod and major metabolites in subjects with mild, moderate, and severe hepatic impairment (HI) compared with demographically-matched healthy...
Elevated fractional exhaled nitric oxide (FeNO) is a clinical indicator of uncontrolled asthma in children receiving inhaled corticosteroids [0.03%]
呼出气一氧化氮（FeNO）水平升高是儿童使用吸入性皮质激素治疗仍不能控制哮喘的临床指标
Sha-Sha Yin,Hong Liu,Xing Gao
Sha-Sha Yin
Objective: Our study aims to explore the correlation between fractional exhaled nitric oxide (FeNO) and inhaled corticosteroids (ICS) efficacy in childhood bronchial asthma (BA). ...
An open-label, multiple-dose study to assess the pharmacokinetics and tolerability of sitagliptin/metformin fixed-dose combination (FDC) tablet in healthy Chinese adult subjects [0.03%]
西格列汀二甲双胍固定剂量复方片在中国健康受试者中的药代动力学及耐受性试验：多次给药开放式临床试验
Xia Chen,Qian Zhao,Jianyan Zhang et al.
Xia Chen et al.
Aim: This study investigated the pharmacokinetics of sitagliptin and metformin after multiple oral doses of the sitagliptin/metformin fixed-dose combination (MK0431A) tablet in healthy Chinese volunteers. ...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2016 Sep;54(9):705-11. DOI:10.5414/CP202646 2016
Effects of paclitaxel liposome and capecitabine in the treatment of advanced gastric cancer by clinical observation [0.03%]
临床观察胸腹联合路径组与腹_pathesis路径组治疗手汗症疗效及安全性
Mingjie Lu,Tongshan Wang,Jian Wang
Mingjie Lu
Objective: To evaluate the clinical effectiveness and side effects of paclitaxel liposome and capecitabine in the treatment of 34 cases with advanced gastric cancer. ...
Bioequivalence and adhesion evaluation of transdermal clonidine following a change in excipient supplier [0.03%]
凝血酸经皮吸收剂辅料供应商变更后的生物等效性及黏着性评价研究
Jerome Ehrlich,Bonnie Beck,Ralf Thiedmann et al.
Jerome Ehrlich et al.
Objective: To evaluate the bioequivalence (BE), safety, tolerability, and adhesion of Oppanol® polyisobutylene (PIB)-containing transdermal therapeutic system (TTS) formulation (test treatment, T) with VistanexTM PIB-con...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2016 Oct;54(10):816-24. DOI:10.5414/CP202563 2016
Advantage of population pharmacokinetic method for evaluating the bioequivalence and accuracy of parameter estimation of pidotimod [0.03%]
人群药动学方法评价匹多莫德生物等效性及参数估计准确性的优势分析
Jihan Huang,Mengying Li,Yinghua Lv et al.
Jihan Huang et al.
Objective: This study was aimed at exploring the accuracy of population pharmacokinetic method in evaluating the bioequivalence of pidotimod with sparse data profiles and whether this method is suitable for bioequivalence...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2016 Sep;54(9):682-92. DOI:10.5414/CP202548 2016
Pharmacokinetic model analysis of interaction between phenytoin and capecitabine [0.03%]
苯妥英与卡培他滨相互作用的药代动力学模型分析
Shohei Miyazaki,Hiroki Satoh,Masayuki Ikenishi et al.
Shohei Miyazaki et al.
Objective: Recent reports have shbown an increase in serum phenytoin levels resulting in phenytoin toxicity after initiation of luoropyrimidine chemotherapy. To prevent phenytoin intoxication, phenytoin dosage must be adj...