Drug utilization and blood pressure control in ambulatory hypertensive patients: focus on those with compelling indications [0.03%]
门诊高血压患者药物使用及血压控制情况：关注有指征的患者群
Aduragbeno D A Adedapo,Onyinye O Akunne,Olulola O Oladapo et al.
Aduragbeno D A Adedapo et al.
Objective: Compelling indications require the use of specific antihypertensive drug classes and often two or more antihypertensive medications for blood pressure (BP) control. This study assessed drug utilization patterns...
Staphylococcus aureus osteo-articular infection: usefulness of the determination of daptomycin serum concentration to explain a treatment failure [0.03%]
万古霉素血药浓度测定解释治疗失败的骨关节瘤型金黄色葡萄球菌感染患者的达托霉素血药浓度测定价值
Sylvain Barreau,Sihem Benaboud,Solen Kernéis et al.
Sylvain Barreau et al.
We report two cases of treatment failure in patients with osteoarticular infection associated with Staphylococcus aureus bacteremia and receiving daptomycin. Using a published population-pharmacokinetic model and daptomycin blood level in t...
The matricellular ligand Cyr61 contributes to the metastatic spread of tumors by activating integrin VLA-4, independently of thiol redox modulation [0.03%]
基质细胞因子Cyr61通过活化整合素VLA-4促进肿瘤转移，独立于硫醇氧化还原调节机制
Sebastian G Hoß,Martin Schlesinger,Gerd Bendas
Sebastian G Hoß
Anke Booker,Louis Jacob,Jens Bohlken et al.
Anke Booker et al.
Background/aims: To analyze the duration of treatment with antipsychotics in German dementia patients. Methods: This study included pat...
Expert consensus on the use of liraglutide in the treatment of diabetes in internal medicine [0.03%]
内科糖尿病用药——利拉鲁肽专家共识
Carlos Calvo Gómez,Ricardo Gómez-Huelgas,Joan Lima Ruiz et al.
Carlos Calvo Gómez et al.
Background: Type 2 diabetes mellitus (DM2) is a disease of epidemic proportions. In the adult Spanish population, prevalence of DM2 is nearly 14%, which makes its monitoring and treatment imperative. Liraglutide has achie...
Comparative analysis of the efficacy of low- and moderate-intensity statins in Korea [0.03%]
韩国低强度和中等强度他汀类药物有效性的比较分析
Hun-Sung Kim,Hyeseon Lee,Bumjoon Park et al.
Hun-Sung Kim et al.
Purpose: The American College of Cardiology/American Heart Association (ACC/AHA) guidelines are based on studies with a limited number of Asian subjects; therefore, they are difficult to apply to Asian patients, including...
Comparative effectiveness of histamine-2 receptor antagonists as short-term therapy for gastro-esophageal reflux disease: a network meta-analysis [0.03%]
短期治疗反流病的组胺-2受体拮抗剂类药物的有效性比较：网络meta分析研究
Feng Zhao,Sheng Wang,Lin Liu et al.
Feng Zhao et al.
To evaluate the efficacy of members of the H2RA family for the treatment of gastro-esophageal reflux disease (GERD). We performed a thorough electronic search on PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials (CENTRA...
Bioequivalence assessment of two pregabalin capsules in healthy Mediterranean Arab volunteers [0.03%]
两种普瑞巴林胶囊在健康地中海阿拉伯志愿者中的生物等效性评估
Abdel Naser Zaid,Naim Kittana,Ayman Mousa et al.
Abdel Naser Zaid et al.
Background: Treatment of neuropathic pain has always been challenging, not only from the pharmaco-therapeutic/toxicological point of view, but also due to the unpredictable pharmacokinetic (PK) variations among different ...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2016 Sep;54(9):723-31. DOI:10.5414/CP202552 2016
Long-term impact of therapeutic drug monitoring on the risk of hypoglycemia in HOCM patients on cibenzoline therapy [0.03%]
血药浓度监测对接受丙苯唑啉治疗的肥厚型心肌病患者低血糖风险长期影响的研究
Yutaro Mukai,Kyoichi Wada,Mai Fujimoto et al.
Yutaro Mukai et al.
Objective: The purpose of this study was to evaluate the long-term impact of therapeutic drug monitoring (TDM) services on the risk of hypoglycemia in cibenzoline therapy. In addition, we evaluated the impact of changes i...
Amoxicillin-induced aseptic meningitis: case report and review of published cases [0.03%]
阿莫西林所致无菌性脑膜炎一例及文献复习
Viktorija Erdeljić Turk,Iveta Šimić,Ksenija Makar-Aušperger et al.
Viktorija Erdeljić Turk et al.
Objective: Amoxicillin-induced aseptic meningitis (AIAM) is an extremely rare adverse reaction with only 12 reported cases. The term aseptic meningitis refers to patients who have clinical and laboratory evidence for meni...