Reversible hard palate hyperplasia associated with amlodipine use: case report [0.03%]
与氨氯地平使用有关的可逆性硬腭增生：病例报告
Xinwen Wang,Qing Liu,Guangying Dong et al.
Xinwen Wang et al.
Calcium channel blockers (CCBs) are medications often used in the clinical management of hypertension and coronary artery disease. Gingival enlargement is a common side effect of CCB administration with no other oral tissue hyperplasia bein...
Christophe Mallet,Claude Dubray,Christian Dualé
Christophe Mallet
This short review focuses on the recent drug development of FAAH inhibitors, as recent serious adverse events have been reported in a phase I study with a compound of this class. The authors overview the potential interest in targeting FAAH...
Induced next-day somnolence in an elderly patient taking suvorexant concomitantly with diltiazem [0.03%]
苏沃雷塞联合地尔硫卓引起的老年人日间嗜睡事件
Atsuko Shihyakugari,Satoko Hori,Akiko Miki et al.
Atsuko Shihyakugari et al.
Objective: To present the first case of induced next-day somnolence in a patient taking suvorexant concomitantly with diltiazem. Case summary: ...
Veronika Luger,Frank Feistle,Gerhard Feistle et al.
Veronika Luger et al.
The book "Facies dolorosa" by Hans Killian, first published in 1934 and later in 1956 and 1967 as extended and annotated versions, comprises ~ 70 photographs depicting facial expressions of patients suffering from various diseases. The phot...
Effects of cardiovascular drugs on TSH serum levels in patients on replacement therapy after thyroidectomy [0.03%]
心血管药物对甲状腺切除术后替代治疗患者TSH血清水平的影响
Marija Andjelkovic,Slobodan Jankovic,Marina Mitrovic et al.
Marija Andjelkovic et al.
Objective: Hypothyroidism is one of most common endocrine disorders resulting from deficiency of thyroid hormones. The aim of our study was to investigate whether cardiovascular drugs as well as gender, age, body-mass ind...
Pharmacokinetics of a nanocrystal-containing megestrol acetate formulation: a single-dose, randomized, open-label, 2-part, 2-period crossover study in healthy Korean subjects [0.03%]
含纳米晶体的醋酸甲地孕酮制剂的药代动力学：在健康韩国受试者中的单次给药、随机开放标签两部分两周期交叉试验
Dong Woo Chae,Hankil Son,Jinju Guk et al.
Dong Woo Chae et al.
Objective: The conventional suspension of megestrol acetate contains micronized megestrol acetate, which was recently discovered to have a disadvantage of decreasing bioavailability when taken in a fasting state. Since m...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2016 Sep;54(9):698-704. DOI:10.5414/CP202574 2016
Population pharmacokinetics of ticagrelor in patients with acute coronary syndromes [0.03%]
急性冠脉综合征患者中替格瑞洛群体药代动力学研究
Jianguo Li,Weifeng Tang,Robert F Storey et al.
Jianguo Li et al.
Objective: Ticagrelor is an orally administered antiplatelet agent used to reduce thrombotic events in patients with acute coronary syndromes. Data from two studies in patients with acute coronary syndromes with large amo...
Dose regimens for Chinese adult liver transplant recipients according to the genetic polymorphisms of CYP2C9, CYP2C19, and CYP3A5 in recipients and donors [0.03%]
受者和供者的遗传多态性指导中国成人肝移植患者的免疫抑制剂个体化用药剂量方案研究
Liqin Zhu,Shasha Liao,Nan Wang et al.
Liqin Zhu et al.
Objective: Genetic polymorphisms of the P450 2C9 enzyme (CYP2C9), CYP2C19 and CYP3A5 gene are known to affect the metabolism of many drugs applied in liver transplant recipients, such as warfarin, voriconazole, and tacrol...
Life threatening biphasic adverse reactions to desmopressin: case report and review of the literature [0.03%]
特异体质者服用德谷加压素引起致命的双相型不良反应的病例报告及文献综述
Lijun Wang,Ruijun Chen,Fang Tian et al.
Lijun Wang et al.
Treatment with desmopressin diacetate arginine vasopressin (DDAVP) and its withdrawal are associated with side effects. We present a rare case of severe biphasic adverse reactions induced by DDAVP and its withdrawal in a 63-year-old female ...
Treatment of depression in patients with cardiovascular diseases by German psychiatrists [0.03%]
德国精神病学家对心血管疾病患者抑郁的治疗
Marcel Konrad,Louis Jacob,Michael A Rapp et al.
Marcel Konrad et al.
Objective: To estimate the prevalence and the type of antidepressant medication prescribed by German psychiatrists to patients with depression and cardiovascular diseases (CVD). ...