Predictors of response to ipragliflozin treatment in patients with type 2 diabetes mellitus [0.03%]
预测2型糖尿病患者吡格列 florin治疗反应的指标研究
Kenta Okada,Kazuhiko Kotani,Ken Ebihara et al.
Kenta Okada et al.
Objective: The aim of the present study was to investigate the efficacy and safety of ipragliflozin treatment on glycemic control in patients with type 2 diabetes mellitus (T2DM). ...
A bioequivalence study of two omeprazole formulations in healthy male volunteers [0.03%]
健康男性志愿者中两种奥美拉唑制剂的生物等效性研究
Yu Kyong Kim,Seonghae Yoon,Kyung-Sang Yu et al.
Yu Kyong Kim et al.
Objective: This study had a single-dose, randomized, open-label, 2-period, and 2-sequence crossover design to evaluate pharmacokinetic (PK) bioequivalence between the test and reference formulations. ...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2016 Nov;54(11):928-934. DOI:10.5414/CP202580 2016
Relationship of microRNA 616 gene polymorphism with prognosis of patients with premature coronary artery disease [0.03%]
微小核糖核酸616基因多态性与早发冠心病患者预后的关系
Yan Zhang,Shijie Wang,Yongqin Li et al.
Yan Zhang et al.
Objective: To investigate the relationship of microRNA 616 (has-miR-616) single nucleotide polymorphisms (SNPs) and its target gene paraoxonase 1 (PON 1) with the prognosis of patients with premature coronary artery disea...
Research on radiotherapy at different times of the day for inoperable cervical cancer [0.03%]
不可手术宫颈癌不同时间段放疗的临床研究
Li Chang,Lan Li,Wenhui Li et al.
Li Chang et al.
Purpose: To investigate the radiation effects and acute damage in inoperable cervical cancer patients irradiated at different times as well as the underlying mechanisms. ...
Gastrointestinal bleeding risk of non-vitamin K oral anticoagulants is similar to warfarin - a Japanese retrospective cohort study [0.03%]
日本回顾性队列研究：非维生素K口服抗凝药物的胃肠出血风险与华法林相似
Tsuguru Shirai,Takatsugu Yamamoto,Kazuo Kawasugi et al.
Tsuguru Shirai et al.
Background and aim: Although several non-vitamin K oral anticoagulants have been developed to prevent cardiogenic thrombosis, the status of hemorrhagic complications in the clinical setting among Asian populations, includ...
Pharmacokinetics and tolerability of intravenous ibuprofen injection in healthy Chinese volunteers: a randomized, open-label, single- and multiple-dose study [0.03%]
静脉注射吲哚美辛在健康中国受试者中的药代动力学和耐受性：一项随机、开放标记的单次及多次给药研究
Huili Zhou,Wei Xu,Guolan Wu et al.
Huili Zhou et al.
Objective: Recently a formulation of intravenous (IV) ibuprofen was developed in China for management of mild to moderate pain in patients who could not take oral medications or where intravenous administration was prefer...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2016 Nov;54(11):904-913. DOI:10.5414/CP202603 2016
Effect of ulinastatin on serum inflammatory factors in Asian patients with acute pancreatitis before and after treatment: a meta-analysis [0.03%]
乌司他丁对亚洲急性胰腺炎患者治疗前后的血清炎症因子的影响的 Meta 分析
Ling-Zhang Wang,Ming-Yu Luo,Jin-Shan Zhang et al.
Ling-Zhang Wang et al.
Objective: We applied a meta-analysis to explore the effect of ulinastatin (UTI) on the serum levels of C-reactive protein (CRP), interleukin 6 (IL-6), and tumor necrosis factor alpha (TNF-α) in Asian patients with acute...
Rifampicin-induced antineutrophil cytoplasmic antibody-positive vasculitis: a case report and review of the literature [0.03%]
利福平诱导的抗中性粒细胞胞浆抗体阳性血管炎一例及文献复习
Guiyi Ji,Xuemei Zeng,Andrew J Sandford et al.
Guiyi Ji et al.
Antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) is a pauci-immune necrotizing vasculitis that involves small vessels. Herein, we report an extremely rare case of rifampicin (RFP)-induced AAV. A 42-yearold female was tra...
Sedation and use of analgesics in endoscopic retrograde cholangiopancreatography: a double-blind comparison study of meperidine/midazolam, remifentanil/ midazolam, and remifentanil alone [0.03%]
关于急诊内镜逆行胰胆管造影中使用镇痛药和镇静剂的双盲对比研究：美普梯宁/咪达唑仑、瑞菲太尼/咪达唑仑与单用瑞菲太尼的效果比较
Jinhua Zhang,Yong Huang,Zhao Li et al.
Jinhua Zhang et al.
Purpose: To compare the efficacy and remifentanil with midazolam for conscious sedation during endoscopic retrograde cholangiopancreatography (ERCP). Meth...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2016 Nov;54(11):872-879. DOI:10.5414/CP202408 2016
Meperidine-induced QTc-interval prolongation: prevalence, risk factors, and correlation to plasma drug and metabolite concentrations [0.03%]
美沙酮致QTc间期延长：发生率、风险因素及与血药和代谢产物浓度的相关性
Guillermo Alberto Keller,María Cecilia Villa Etchegoyen,Nicolás Fernández et al.
Guillermo Alberto Keller et al.
A prolongation of the QTc-interval has been described for several opioids, including pethidine (meperidine). Objective: To evaluate in the clinical settin...