Prevalence of aspirin resistance in patients with type II diabetes: a descriptive-analytical study [0.03%]
糖尿病患者阿司匹林抵抗的流行病学研究：描述性分析研究
Rahimeh Eskandarian,Mohammadreza Razavi,Abolfazal Fattah et al.
Rahimeh Eskandarian et al.
Background: Aspirin resistance is one of the most important factors for arterial thrombotic events in diabetic patients. This study aimed to evaluate aspirin resistance in diabetic patients. ...
Individualized dosing of enoxaparin in a morbidly obese patient by monitoring the anti-factor Xa [0.03%]
通过监测抗因子Xa活性对病态肥胖患者进行依诺肝素的个体化剂量调整
Faizan Mazhar,Yousif Ahmed
Faizan Mazhar
Diclofenac systemic bioavailability of a topical 1% diclofenac + 3% menthol combination gel vs. an oral diclofenac tablet in healthy volunteers: a randomized, open-label, crossover study [0.03%]
一项在健康志愿者中评估1%氟比洛芬凝胶剂联合3%薄荷醇与口服氟比洛芬片生物利用度的随机开放交叉研究：
Sebastian A Moreira,D Jeffery Liu
Sebastian A Moreira
Objective: Evaluate systemic exposure with repeated topical application of a fixed-combination topical gel product containing 1% diclofenac sodium and 3% menthol in either of 2 formulation packages relative to oral admini...
A case of multiple vertebral compression fractures due to glucocorticoid-induced osteoporosis in a pediatric patient with nephrotic syndrome [0.03%]
一名肾病综合征患儿因糖皮质激素所致骨质疏松症并发多发椎体压缩性骨折病例报告
Akira Ashida,Yuko Fujii,Hideki Matsumura et al.
Akira Ashida et al.
Introduction: Glucocorticoid therapy has a number of adverse effects, among which osteoporosis and bone fracture can be major complications. Immunosuppressive therapy for nephrotic syndrome is effective and can help to re...
Comparative pharmacodynamic effects of two clopidogrel formulations under steady-state conditions in healthy Thai volunteers [0.03%]
两种氯吡格雷制剂在健康泰国受试者稳态条件下的药动学比较研究
Nontaya Nakkam,Somsak Tiamkao,Sirimas Kanjanawart et al.
Nontaya Nakkam et al.
Objective: Clopidogrel is a commonly used antiplatelet aggregation agent. Compared with the reference clopidogrel product, most commercially available generic clopidogrel products contain different crystalline forms of cl...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2017 Feb;55(2):177-185. DOI:10.5414/CP202723 2017
Single- and multiple-dose pharmacokinetics and tolerability of a paroxetine controlled-release tablet in healthy Chinese subjects [0.03%]
单剂量和多剂量位厚朴酚胶囊在中国健康受试者体内的药代动力学及耐受性研究
Rui Chen,Kai Shen,Pei Hu
Rui Chen
Objectives: To evaluate the pharmacokinetics of paroxetine controlled-release (CR) tablets after single and multiple oral administrations and to evaluate its safety profile in healthy Chinese subjects. ...
A study comparing the safety and efficacy of febuxostat, allopurinol, and benzbromarone in Chinese gout patients: a retrospective cohort study [0.03%]
中国高尿酸血症患者非布司他、别嘌醇及苯溴马隆疗效和安全性的比较：回顾性队列研究
Qiao Zhou,Jiang Su,Ting Zhou et al.
Qiao Zhou et al.
Objective: To evaluate and compare the safety and efficacy of three urate lowering agents: febuxostat, allopurinol, and benzbromarone, when used to treat Chinese gout patients. ...
Post-authorization changes in the safety and efficacy assessment, recommended indications, and drug quality profile of adalimumab: a chronological overview [0.03%]
阿达木单抗安全性和有效性评价的上市后变化、推荐适应症及药品质量概况的历时性概述
Gergely Iványi,Romána Zelkó
Gergely Iványi
Objective: The intention of the present study was to demonstrate the postauthorization changes of adalimumab (European trade name: Humira), evaluating the variations in its safety, efficacy, and quality profile. ...
Wolfgang Rathmann,Marcin Czech,Edward Franek et al.
Wolfgang Rathmann et al.
Aims: To compare short-term basal insulin therapy persistence and its predictors in Poland and Germany. Methods: Persistence was define...
Pharmacokinetic comparison and bioequivalence evaluation of two 10-mg baclofen formulations in healthy male subjects [0.03%]
两种10mg巴氯芬制剂的药动学比较及生物等效性评价
Sumin Yoon,SeungHwan Lee,Kyung-Sang Yu et al.
Sumin Yoon et al.
Backgrounds: Baclofen is used as a skeletal muscle relaxant for multiple sclerosis patients. It depresses the transmission of monosynaptic and polysynaptic reflex by stimulating GABAβ (gamma-aminobutyric acid) receptors....
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2017 Feb;55(2):194-200. DOI:10.5414/CP202760 2017