Impact of extracorporeal membrane oxygenation on antituberculosis drug concentrations: A case study and pharmaceutical care strategies [0.03%]
体外膜氧合对抗结核药血药浓度影响的个案研究及药学干预策略
Yidan Xu,Fei Lv,Xing Yu
Yidan Xu
Background: Extracorporeal membrane oxygenation (ECMO) provides life support for critically ill tuberculosis (TB) patients. However, during ECMO therapy, significant fluctuations in the plasma concentration of anti-TB dru...
Effect of inhaled corticosteroid with oral montelukast and levocetirizine in asthma: A population-based study [0.03%]
inhaled皮质类固醇联合口服蒙特鲁卡斯和左西替利嗪在哮喘中的效果：基于人口的调查研究
Myunghee Park,Seong-Dae Woo,Minae Park et al.
Myunghee Park et al.
Introduction: Asthma is a chronic disease that requires careful management, and its exacerbations can be life-threatening. The aim of this study was to ascertain whether inhaled corticosteroids (ICS)-containing inhaler in...
Parenteral replacement therapy with iron dextran or ferumoxytol in patients with iron deficiency [0.03%]
铁缺乏患者输注右旋糖酐铁或蔗糖铁的替代疗法研究
Giampaolo Talamo,Rintaro Onishi,Rahul Anand et al.
Giampaolo Talamo et al.
Objective: To evaluate the changes in hematological parameters after replacement therapy with either iron dextran or ferumoxytol in patients with iron deficiency. ...
Piperacillin/tazobactam-induced reversible pancytopenia in a pregnant patient: A case report [0.03%]
产育龄期患者哌拉西林他唑巴坦致全血细胞减少1例报告
Ning He,Shiyu Wang,Qingmao Luo et al.
Ning He et al.
Hematologic responses (< 1%) to piperacillin/tazobactam were uncommon, and mostly reported in non-pregnant adults. The use of piperacillin/tazobactam during pregnancy is considered to be moderately safe for the human embryo-fetus (pregnancy...
The guanylate cyclase stimulator vericiguat: Insights and adverse events from a FAERS-based pharmacovigilance study [0.03%]
鸟苷酸环化酶刺激剂维卡格鲁：基于FAERS的药物警戒研究的见解和不良事件
Jia Tang,Bing Lv,Jingchun Han et al.
Jia Tang et al.
Background: Since its approval by the U.S. Food and Drug Administration in January 2021, vericiguat, a novel soluble guanylate cyclase stimulator, has been increasingly utilized in the treatment of heart failure with redu...
Pavan Kumar Reddy Kalluru,Apoorva Cherukuri,Deekshitha Kuchi et al.
Pavan Kumar Reddy Kalluru et al.
Obesity is a global health issue that impacts millions of people worldwide. Semaglutide is a glucagon-like peptide-1 receptor agonist that was initially developed as a treatment for type 2 diabetes mellitus under the brand name Ozempic. Add...
Dose optimization of linezolid among surgical patients: A population pharmacokinetic study [0.03%]
利奈唑胺在手术患者中的剂量优化：群体药代动力学研究
Mustajab Ali Naseer,Muhammad Aamir,Hajira Bilal et al.
Mustajab Ali Naseer et al.
Background: Linezolid is classified under the reserve group of antibiotics, and it exerts its antibacterial activity by disrupting protein synthesis. Clinically, linezolid is used for treatment of severe infections caused...
Comparison and evaluation of safety, pharmacokinetics, and pharmacodynamics of two regadenoson injections in healthy Chinese subjects [0.03%]
两种瑞加诺生注射液在健康受试者中的安全性、药代动力学及药效学对比评估研究
Yi Liu,Cao-Yang Wang,Hai-Wen Wang et al.
Yi Liu et al.
Objective: This study evaluated and compared the safety, pharmacokinetics, and pharmacodynamics of regadenoson injection (test) and regadenoson original injection (Lexiscan, reference) in healthy Chinese subjects. ...
Cardiotoxicity associated with antifungal agents: A pharmacovigilance analysis of the FDA Adverse Event Reporting System [0.03%]
基于FDA不良事件报告系统的抗真菌药物心血管毒性的药物流行病学分析
Dongnan Cao,Chunyan Wei,Yanling Yuan et al.
Dongnan Cao et al.
Objective: The aim of this study was to analyze the cardiotoxicity associated with antifungal agents based on data from the U.S. Food and Drug Administration Adverse Event Reporting System (FAERS). ...
Prediction of anti-epileptic drug response of patients based on peripheral blood RNA profiles and machine learning [0.03%]
基于外周血RNA谱型和机器学习的癫痫患者抗癫痫药物反应预测模型研究
Zhi-Dong Liu,Zhao-Yang Kou,Lin Guo
Zhi-Dong Liu
Objective: In this study, we aimed to develop a method for predicting the response of patients to three commonly used anti-epileptic drugs (AEDs), namely, carbamazepine, phenytoin, and valproate, using machine learning mo...