Evaluation of the risk factors for the failure of a single prophylactic dose of anticholinergic drugs for irinotecan-induced cholinergic symptoms [0.03%]
评估单次预防性抗胆碱能药物治疗伊立替康引起的胆碱能症状失败的风险因素
Takuya Watanabe,Yoshitaka Saito,Yoh Takekuma et al.
Takuya Watanabe et al.
Objective: Irinotecan (IRI) is an anticancer drug that is frequently used to treat colorectal, gastric, and pancreatic cancers. Its side effects include cholinergic symptoms, such as diarrhea, abdominal pain, nausea, and ...
Network pharmacology analysis and clinical efficacy of the traditional Chinese medicine Bu-Shen-Jian-Pi. Part 3: Alleviation of hypoxia, muscle-wasting, and modulation of redox functions in amyotrophic lateral sclerosis [0.03%]
补肾健脾中药网络药理学分析及其临床疗效。第3部分：缓解肌萎缩侧索硬化中的缺氧、肌肉消瘦及调节氧化还原功能作用分析
Rui Li,Xiaojing Han,Qiudong Wang et al.
Rui Li et al.
Objective: The aim of this clinical study is to obtain evidence for the clinical efficacy of Bu-Shen-Jian-Pi formula (BSJP), a traditional Chinese medicine, used for the treatment of amyotrophic lateral sclerosis, a relat...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2024 Apr;62(4):169-177. DOI:10.5414/CP204520 2024
Network pharmacology analysis and clinical efficacy of the traditional Chinese medicine Bu-Shen-Jian-Pi. Part 2: Modulation of hypoxia, redox status, and mitochondrial protection in a neuroblastoma cell line, SH-SY5Y [0.03%]
基于网络药理学分析和传统中医补肾健脾的临床疗效。第二部分：在神经母细胞瘤细胞系SH-SY5Y中对缺氧、氧化还原状态和线粒体保护的调节作用
Wenli Yuan,Jiacheng Lin,Jun Wang et al.
Wenli Yuan et al.
Objective: To examine the mitochondrial protective effects of icariin, naringenin, kaempferol, and formononetin, potentially active agents in Bu-Shen-Jian-Pi formula (BSJP) identified using network pharmacology analysis. ...
Balancing efficacy and adverse reactions using everolimus in a patient with metastatic malignant insulinoma: Case report [0.03%]
使用依维莫司治疗转移性恶性胰岛素瘤患者的疗效与不良反应之间的平衡：病例报告
Siham Rouf,Khadija Boujtat,Tijani El Harroudi et al.
Siham Rouf et al.
Introduction: Malignant insulinoma is a rare neuroendocrine tumor responsible for excessive insulin secretion and life-threatening hypoglycemia episodes. Computed tomography (CT) of the abdomen can identify a pancreatic t...
Comparison of vancomycin area under the curve calculated based on Bayesian approach versus equation-based approach [0.03%]
贝叶斯法和公式法计算去甲万古霉素曲线下面积的比较
Eojin Lee,Uijeong Yu,Ji In Park et al.
Eojin Lee et al.
Objective: Area under the curve (AUC)-based vancomycin dose adjustment is recommended to treat methicillin-resistant Staphylococcus aureus (MRSA) infections. AUC estimation methods include Bayesian software programs and s...
Clinical implications and future prospects of levonorgestrel and piroxicam as a combined emergency contraceptive regimen [0.03%]
左炔诺孕酮和吡罗昔康作为联合紧急避孕方案的临床意义及发展前景
Jiawei Ke,Jingrui Cai,Xiaolin Liu et al.
Jiawei Ke et al.
Network pharmacology analysis of the renal protective effects of bracken (Pteridium aquilinum) using experimental data obtained in an avian (quail) hyperuricemia model [0.03%]
雁石蚕蛾草（鳞毛蕨）对肾脏的保护作用的网络药理学分析使用鸟类（鹌鹑）高尿酸血症模型获得的实验数据
Sheng Li,Nai Dong Chen,Ya Qin Bu et al.
Sheng Li et al.
Objective: To investigate the nephroprotective potential of orally administered bracken Pteridium aquilinum extract against renal damage in quails, induced by a high-purine diet, to form a foundation for subsequent clinic...
Cost-effectiveness analysis of mecapegfilgrastim and recombinant human granulocyte stimulating factor for primary prophylaxis of chemotherapy-induced neutropenia in non-small cell lung cancer [0.03%]
甲磺酸艾拉司琼与重组人粒细胞刺激因子用于非小细胞肺癌化疗诱导性中性粒细胞减少症的一级预防的成本效果分析
Yong-Li Gu,Zeng-Xian Sun,Ying Sun et al.
Yong-Li Gu et al.
Objective: To evaluate the efficacy, safety, and economics of mecapegfilgrastim and recombinant human granulocyte colony-stimulating factor (rhG-CSF) in the primary prevention of chemotherapy-related neutropenia in non-sm...
Network pharmacology analysis and clinical efficacy of the traditional Chinese medicine Bu-Shen-Jian-Pi. Part 1: Biogenic components and identification of targets and signaling pathways in amyotrophic lateral sclerosis patients [0.03%]
补肾健脾中药的网络药理学分析及其临床疗效。第一部分：生物源性成分以及肌萎缩侧索硬化症患者靶点和信号通路的识别
Jiacheng Lin,Jun Wang,Chenghui Wang et al.
Jiacheng Lin et al.
Background: There is evidence that Bu-Shen-Jian-Pi (BSJP), a traditional Chinese medicine, has curative effects in patients suffering from amyotrophic lateral sclerosis (ALS), a progressive and potentially fatal hypoxic c...