Is compressed colchicine tablet superior to other colchicine preparations in patients with familial Mediterranean fever? [0.03%]
压缩秋水仙碱片与地中海贫血患者的其他秋水仙碱制剂相比更优吗？
İbrahim Vasi,Rıza Can Kardaş,Derya Yıldırım et al.
İbrahim Vasi et al.
Aims: The aim of our study is to evaluate the differences in effectiveness, dosage, and side effect profiles in the use of colchicine preparations and evaluate the superiority of compressed colchicine tablets in familial ...
Effect of pre-treatment with EGFR-TKIs on immune checkpoint inhibitor-associated interstitial lung disease in lung cancer patients: Analysis using a Japanese claims database [0.03%]
EGFR-TKI预处理对肺癌患者免疫检查点抑制剂相关间质性肺疾病的影响：基于日本理赔数据库的分析
Naoto Okada,Hirofumi Hamano,Kenta Yagi et al.
Naoto Okada et al.
Background: Immune checkpoint inhibitors (ICI) and epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKI) are key drugs for the treatment of EGFR mutation-positive lung cancer. While previous studies repor...
Monitoring of blood levels in patients administered CYP3A4 inhibitor during the maintenance phase of venetoclax administration [0.03%]
CYP3A4抑制剂联合治疗期间维奈克拉维持期的药物浓度监测研究
Toshiki Kubo,Shunsuke Matsuo,Rintaro Sogawa et al.
Toshiki Kubo et al.
Objective: Venetoclax, an oral B-cell lymphoma-2 inhibitor, necessitates dose adjustment when combined with a CYP3A4 inhibitor; however, the dosing regimen remains unclear on adding a CYP3A4 inhibitor after venetoclax adm...
German longitudinal prescription database (LRx): Description of characteristics, use in pharmacoepidemiological research, and limitations [0.03%]
德国纵向处方数据库(LRx)：特征描述、药物流行病学研究中的应用及其局限性
Karel Kostev,Ying Wang,Robert Singh et al.
Karel Kostev et al.
Large databases have played a critical role in pharmacoepidemiological research in the last decade, with this role likely to gain further importance in the future. The aim of the present paper is to describe the characteristics, the recent ...
Xia Wu,Lutao Zhang,Chuanping Wang
Xia Wu
A 70-year-old male taking venlafaxine for depression developed interstitial pneumonia and was admitted with shortness of breath and dyspnea. A computed tomography (CT) chest scan showed diffuse multiple lung lesions in both lungs, suggestin...
Predictors for non-attainment of meropenem target concentrations when treating infections in critically ill patients [0.03%]
预测危重病患者感染时美罗培南药物浓度未达靶浓度的影响因素
Shao Jun Zheng,Yifan Xu,Nai Dong Chen et al.
Shao Jun Zheng et al.
Background: Failure to achieve target concentrations of β-lactam antibiotics is not uncommon despite administration of high doses. The objective of this study was to identify risk factors predicting non-attainment of β-...
Analysis of risk factors for hypoglycemia in patients with gastrointestinal bleeding induced by somatostatin for injection and establishment of the prediction model [0.03%]
注射奥曲肽治疗上消化道出血患者低血糖风险因素分析及预测模型构建
Hong Zhang,Lei Chen,Xiaoying Wang et al.
Hong Zhang et al.
Objectives: This study aimed to explore the risk factors of hypoglycemia in patients with gastrointestinal bleeding caused by somatostatin for injection and to establish a prediction model based on logistic regression com...
Phillyrin sensitizes lung cancer cells to ferroptosis through inhibiting FTH1/SLC7A11 axis [0.03%]
Phillyrin通过抑制FTH1/SLC7A11轴增强肺癌细胞铁死亡敏感性
Xu Tang,Jiajia Teng,Keyin Lu
Xu Tang
Ferroptosis is a newly found form of non-apoptotic regulated cell death that is essential for cancer progression. Phillyrin (PHN), an effective lignan glycoside of Forsythia suspensa, has been explored as a potential anticancer agent in som...
Leukopenia associated with lamotrigine initiation after COVID-19 vaccine booster: A case report and literature review [0.03%]
与新冠疫苗加强剂接种后启动拉莫三嗪相关的白细胞减少症一例及其文献复习
Tsukasa Murata,Katsuaki Uno,Miki Ito et al.
Tsukasa Murata et al.
Adverse lamotrigine effects are more likely with concomitant use of antiepileptic drugs, rapid dose titration, and multiple drug use, highlighting the importance of measuring its concentration. Here, lamotrigine was administered the day aft...
Potential drug-drug interactions in a multi-center study of death cases of COVID-19: The significance of appropriate drug choice [0.03%]
一项关于COVID-19死亡病例的多中心研究中潜在的药物相互作用：合理用药的选择意义
Ayda Esmaeili,Zahra Niazkhani,Khadijeh Makhdoomi et al.
Ayda Esmaeili et al.
Objectives: The prevalence, types, severity, risk ratings, and common pairs of involved drugs, and the most important potential drug-drug interactions (pDDIs) in coronavirus disease 2019 (-COVID-19) deceased cases were ev...