Skin adhesion of a newly developed, bioequivalent rotigotine patch formulation in comparison to the originator product: Results of a multi-center, randomized, crossover trial in patients with Parkinson's disease [0.03%]
一种新型与原研药等效的罗替戈汀透皮贴片在帕金森病患者中的皮肤粘附性：一项多中心、随机交叉试验结果
Wolfgang H Jost,Maggie Wang,Gabriel Wauer et al.
Wolfgang H Jost et al.
Objectives: To demonstrate adequate skin adhesion of a new once-daily rotigotine transdermal patch (ROT-TDS) compared to the originator product (reference) in patients with Parkinson's disease (PD). ...
Identification of factors associated with vancomycin-induced acute kidney injury: A retrospective analysis using the Common Data Model [0.03%]
万古霉素引起的急性肾损伤相关因素的识别：使用通用数据模型的回顾性分析
Sang-In Park,Jung-Kyeom Kim,Uijeong Yu et al.
Sang-In Park et al.
Objective: Previous findings on predictors of vancomycin-induced acute kidney injury (AKI) are inconsistent. We aimed to identify the predictors of vancomycin-induced AKI using the Observational Medical Outcome Partnershi...
Retrospective evaluation of medical information for predicting tazobactam/piperacillin-induced liver injury [0.03%]
回顾性评价医疗信息以预测他唑巴坦/哌拉西林所致肝损伤的风险
Takahiro Amemiya,Hiroshi Suzuki
Takahiro Amemiya
Objective: Tazobactam/piperacillin is a first-line treatment option for hospital-acquired pneumonia; however, drug-induced liver injury (DILI) is relatively frequently observed with tazobactam/piperacillin in clinical pra...
Comparison of uric acid elevation between aspirin-ticagrelor and aspirin-clopidogrel during dual antiplatelet therapy [0.03%]
双联抗血小板治疗期间阿司匹林替格瑞洛与阿司匹林氯吡格雷的尿酸升高比较研究
Sojin Park,Sangah Chi,Jeong Hoon Yang et al.
Sojin Park et al.
Objective: This study investigated whether serum uric acid levels are more elevated in the aspirin-ticagrelor group than in the aspirin-clopidogrel group. Materials and Materials and methods: We conducted a retrospective ...
A case of a geriatric patient with thrombocytopenia after partial recovery from COVID-19 [0.03%]
一例新冠肺炎部分恢复期出现血小板减少的老年人病例报告
Yukako Hayashi,Kenji Momo,Mutsumi Ando et al.
Yukako Hayashi et al.
The global emergence of -COVID-19 has prompted rapid therapeutic and vaccine advancements; however, clinical evidence remains limited. With around a 50% fatality rate for COVID-19 patients with acute respiratory distress syndrome (ARDS), ea...
Dosing strategy of tacrolimus when co-administered with Wuzhi tablet in renal transplant recipients [0.03%]
肾移植受者服用乌芝片联合他克莫司的用药策略研究
Rui Dai,Yiting Cai,Jun Li et al.
Rui Dai et al.
Objective: Tacrolimus (TAC) is a first-line immunosuppressant to prevent allograft rejection. Wuzhi tablet is widely used as a TAC-sparing agent in China that could significantly elevate TAC exposure. However, insufficien...
Bioequivalence study of two formulations of afatinib dimaleate tablets in healthy subjects under fasting conditions: A randomized, open-label, single-dose, crossover trial [0.03%]
空腹条件下艾氟替尼马来酸两种制剂在健康受试者中的生物等效性试验：一项随机、开放标签、单次给药、双周期交叉试验
Yanping Liu,Lang Lü,Man Xu et al.
Yanping Liu et al.
Objective: To evaluate the bioequivalence of two different afatinib dimaleate formulations in healthy Chinese subjects under fasting conditions and to assess their pharmacokinetic and safety profiles. ...
Randomized Controlled Trial
International journal of clinical pharmacology and therapeutics. 2024 Oct;62(10):479-485. DOI:10.5414/CP204514 2024
Pulmonary fibrosis insights and therapy targets from disease models and administration of the lipophilic diterpene, sodium tanshinone IIA sulfonate: Review and meta-analysis [0.03%]
疾病模型及脂溶性二萜酚硫酸丹参素钠给药对肺纤维化的研究见解和治疗靶点：综述与荟萃分析
Li-Ying Peng,Jun-Jun Shi,Yue Liang et al.
Li-Ying Peng et al.
Pulmonary fibrosis (PF) is a chronic and progressive pulmonary interstitial disease of unknown etiology and is also a sequela in severe patients with the Coronavirus Disease 2019 (COVID-19). Seven databases were systematically searched to e...
Early acute kidney injury after tacrolimus administration in heart transplant recipients receiving basiliximab induction therapy [0.03%]
他克莫司联合巴利昔单抗诱导的心脏移植术后早期急性肾损伤
Megumi Ikura,Tsutomu Nakamura,Kyoichi Wada et al.
Megumi Ikura et al.
Objective: In this study, we aimed to analyze the association among the timing of tacrolimus initiation, time required to reach the target blood concentration, and early acute kidney injury (AKI) after tacrolimus administ...
Najla Dar-Odeh,Ala&#x;a Atef,Yara Flaifl et al.
Najla Dar-Odeh et al.
Objectives: To evaluate the indications and dosing regimens for oral metronidazole monotherapy (OMM) for the management of oral anaerobic infections (OAIs) other than periodontitis. ...