Amelioration of benzo (a) pyrene-induced lung carcinogenesis in strain A mice by diphenylmethyl selenocyanate [0.03%]
姜法茋抑制苯并(a)芘诱导的A品系小鼠肺癌发生的作用研究
Rajat K Das,Sarmistha Banerjee,Sudin Bhattacharya
Rajat K Das
Organoselenocyanates are an important class of chemopreventive agents, which possess antioxidative, antimutagenic and anticarcinogenic properties. In the present study, we used benzo (a) pyrene (BP)-induced lung carcinogenesis model for ass...
Dimethylthetin treatment causes diffuse alveolar lung damage: a pilot study in a sheep model of Continuous Ambulatory Peritoneal Dialysis (CAPD) [0.03%]
二甲基硫醚治疗导致弥散性肺泡损伤：连续流动腹膜透析（CAPD）的羊模型初步研究
Sandy Slow,Madhusudan Vasudevamurthy,Robin Fraser et al.
Sandy Slow et al.
Total plasma homocysteine (Hcy) concentration correlates with risk of vascular disease. Over 80% of chronic renal failure patients have elevated plasma Hcy and a 10-20 times higher incidence of vascular disease. Glycine betaine lowers plasm...
Simona Bussi,Xavier Fouillet,Alberto Morisetti
Simona Bussi
In vivo gadolinium release was evaluated for MultiHance, Omniscan and Gadovist estimating gadolinium content in liver, kidneys, spleen, femur and brain after single or repeated intravenous administrations to rats at 1 mmol/kg. Gadolinium ac...
The alveolar epithelial type I-like cell line as an adequate model for leukocyte migration studies in vitro [0.03%]
肺泡上皮I型样细胞系作为体外白细胞迁移研究的理想模型
Anke Lührmann,Gerhard Bargsten,Meryem Kuzu et al.
Anke Lührmann et al.
The lung is unique as leukocytes not only migrate into the bronchoalveolar space but also return to the parenchyma and then via the lymphatics to the draining lymph node. The aim of this study was to investigate the migration of leukocytes ...
Justyna Szumilo
Justyna Szumilo
N-nitrosomethylbenzylamine (NMBA) is one of the most potent organ-specific carcinogens routinely used in rat esophageal tumorigenesis. The aim of the study was to evaluate NMBA effect on nasal mucosa, one of the non-target organs. NMBA was ...
Copper impairs biliary epithelial cells and induces protein oxidation and oxidative DNA damage in the isolated perfused rat liver [0.03%]
铜可损害胆管上皮细胞并能在隔绝灌流的肝中诱导蛋白质氧化及氧化性DNA损伤
Albena Alexandrova,Anton Kebis,Csilla Misl&#x;anová et al.
Albena Alexandrova et al.
Copper is one of the major metals causing environmental contamination. Previous studies showed that copper induced toxic effects in isolated perfused rat liver models and these effects were associated with lipid peroxidation. Here we invest...
Bioassay by intratracheal instillation for detection of lung toxicity due to fine particles in F344 male rats [0.03%]
短期气管内给药鼻腔暴露法评价细颗粒物所致F344雄性大鼠肺毒性的生物检测法研究
Masanao Yokohira,Hijiri Takeuchi,Keiko Yamakawa et al.
Masanao Yokohira et al.
We have established and documented an in vivo bioassay for detection of hazards with intratracheally instilled fine particles, which can be used for risk assessment of toxicity of materials inhaled into deep lung tissue of humans (Yokohira ...
Interindividual differences in anticancer drug cytotoxicity in primary human glioblastoma cells [0.03%]
人源性胶质母细胞瘤原代细胞中抗肿瘤药物细胞毒性的个体差异
Stéphane Pédeboscq,Béatrice L&#x;Azou,Dominique Liguoro et al.
Stéphane Pédeboscq et al.
Glioblastoma multiforme is a malignant astrocytic tumor characterized by rapid growth, extensive invasiveness and high vascularity. Despite advances in surgical techniques and in the development of new protocols in radio- and chemotherapy, ...
The long-term neurocompatibility of human fibrin sealant and equine collagen as biomatrices in experimental spinal cord injury [0.03%]
人纤维蛋白粘合剂和马胶原作为生物基质在实验性脊髓损伤中的长期神经相容性
Alexander H Petter-Puchner,Wolfgang Froetscher,Reinhild Krametter-Froetscher et al.
Alexander H Petter-Puchner et al.
Introduction: While fibrin sealant (FS) and equine collagen (EC) have been used as scaffold materials in experimental spinal cord injury (SCI), questions concerning neurocompatibility still remain. In this study, we asses...
Immunohistochemical analysis of expressions of hepatic cytochrome P450 in F344 rats following oral treatment with kava extract [0.03%]
口服治疗kahva提取物的大鼠肝细胞色素P450表达的免疫组化分析
Natasha P Clayton,Katsuhiko Yoshizawa,Grace E Kissling et al.
Natasha P Clayton et al.
Kava (Piper methysticum), used for relaxation and pain relief, has been one of the leading dietary supplements and several reports linking hepatic functional disturbances and liver failure to kava have resulted in a ban on sales in Europe a...