T cell infiltration is associated with increased Lyme arthritis in TLR2-/- mice [0.03%]
TLR2缺陷小鼠中T细胞浸润与莱姆关节炎加重有关
Xiaohui Wang,Ying Ma,Alyson Yoder et al.
Xiaohui Wang et al.
C57BL/6 mice deficient in TLR2 develop more severe arthritis following infection with Borrelia burgdorferi than do wild-type C57BL/6 mice, and this increase is suppressed by the simultaneous presence of the scid mutation. This suggested a r...
Rebecca A Brady,Jeff G Leid,Jason H Calhoun et al.
Rebecca A Brady et al.
Understanding the mechanisms implicated in the initial attachment, development, and maturation of a biofilm phenotype are of tremendous importance for their effect on the medical, industrial, and public health arenas. This review explores t...
The role of monocyte/macrophages as vehicles of dissemination of Simkania negevensis: an in vitro simulation model [0.03%]
单核细胞/巨噬细胞作为Simkania negevensis传播载体的作用：一种体外仿真模型
Simona Kahane,Bella Dvoskin,Maureen G Friedman
Simona Kahane
Exposure to Simkania negevensis (Sn), an intracellular microorganism that has been associated with respiratory tract infections in infants and adults, is prevalent. Sn can multiply within free-living amoebae and has been detected in domesti...
A review on the interactions between gut microbiota and innate immunity of fish [0.03%]
鱼类肠道微生物与固有免疫相互作用研究进展
Geovanny D Gómez,José Luis Balcázar
Geovanny D Gómez
Although fish immunology has progressed in the last few years, the contribution of the normal endogenous microbiota to the overall health status has been so far underestimated. In this context, the establishment of a normal or protective mi...
Construction of cholera toxin B subunit-producing Vibrio cholerae strains using the Mariner-FRT transposon delivery system [0.03%]
使用Mariner-FRT转座子递送系统构建产生霍乱毒素亚单位B的霍乱弧菌菌株
Gi-Eun Rhie,Hae-Mi Jung,Jungchan Park et al.
Gi-Eun Rhie et al.
The most widely used oral whole-cell-recombinant B subunit cholera vaccine contains the nontoxic cholera toxin B subunit (CTXB) and either heat- or formalin-killed Vibrio cholerae O1 strains. Vibrio cholerae O1 strains in the vaccine provid...
Role of TLR1 and TLR6 in the host defense against disseminated candidiasis [0.03%]
TLR1和TLR6在宿主抵抗播散性念珠菌病中的作用
Mihai G Netea,Frank van de Veerdonk,Ineke Verschueren et al.
Mihai G Netea et al.
Toll-like receptor-1 (TLR1) and TLR6 are receptors of the TLR family that form heterodimers with TLR2. The role of TLR1 and TLR6 for the recognition of the fungal pathogen Candida albicans was investigated. TLR1 is not involved in the recog...
Effects of cyclooxygenase inhibitors on parasite burden, anemia and oxidative stress in murine Trypanosoma cruzi infection [0.03%]
环氧化酶抑制剂对小鼠克鲁兹锥虫感染的影响：对寄生虫负荷、贫血和氧化应激的作用
Vera L Hideko Tatakihara,Rubens Cecchini,Celso L Borges et al.
Vera L Hideko Tatakihara et al.
Prostaglandins are known to be produced by macrophages when challenged with Trypanosoma cruzi, the etiological agent of Chagas' disease. It is not known whether these lipid mediators play a role in oxidative stress in host defenses against ...
Staphylococcal peptidoglycan initiates an inflammatory response and procoagulant activity in human vascular endothelial cells: a comparison with highly purified lipoteichoic acid and TSST-1 [0.03%]
金黄色葡萄球菌肽聚糖可引发人血管内皮细胞的炎症反应和促凝活性：与高纯度脂磷壁酸和TSST-1的比较
Eva Mattsson,Ruth Heying,Joke S van de Gevel et al.
Eva Mattsson et al.
Staphylococcus aureus is one of the most significant pathogens in human sepsis and endocarditis. A hallmark of these endovascular S. aureus infections is that the coagulation system is triggered by a tissue factor (TF)-dependent pathway. Th...
Catecholamines and sympathomimetic drugs decrease early Salmonella Typhimurium uptake into porcine Peyer's patches [0.03%]
儿茶酚胺和拟交感药物可减少伤寒沙门氏菌早期侵入猪派耶斑区域
David R Brown,Lisa D Price
David R Brown
Peyer's patches of the small intestine serve as inductive sites for mucosal immunity as well as targets for invasive enteropathogens, including Salmonella. Because they are innervated by catecholamine-containing enteric nerves, the hypothes...
Mucosal antibody responses of colonized cattle to Escherichia coli O157-secreted proteins, flagellin, outer membrane proteins and lipopolysaccharide [0.03%]
大肠杆菌O157定植的牛对黏膜抗体反应的影响
Pablo Nart,Nicola Holden,Sean P McAteer et al.
Pablo Nart et al.
The aim of this work was to characterize adaptive mucosal immune responses to Escherichia coli O157:H7 at the principal site of colonization in the bovine species. Following experimental infection, extracts from terminal rectum mucosal samp...