Proteomic analysis of Chlamydia pneumoniae-infected HL cells reveals extensive degradation of cytoskeletal proteins [0.03%]
蛋白质组分析显示，肺炎衣原体感染的HL细胞的细胞骨架蛋白被广泛降解
Kirsi Savijoki,Joni Alvesalo,Pia Vuorela et al.
Kirsi Savijoki et al.
Cytoskeletal proteins of HL cells, following Chlamydia pneumoniae infection, were studied by two-dimensional gel electrophoresis and two-dimensional difference gel electrophoresis. Proteome analyses of HL cells at 48 and 72 h postinfection ...
MyD88 is dispensable for resistance to Paracoccidioides brasiliensis in a murine model of blood-borne disseminated infection [0.03%]
MYD88在巴西副球孢子菌血源性播散感染小鼠模型中的非必需性研究
Angel González,Alberto Yáñez,Daniel Gozalbo et al.
Angel González et al.
We have studied the role of MyD88, an adaptor protein of Toll-like receptors (TLRs), in murine defenses against Paracoccidioides brasiliensis in a model of blood-borne disseminated infection. Wild-type (WT) and MyD88-deficient mice infected...
Discrimination between biothreat agents and 'near neighbor' species using a resequencing array [0.03%]
利用重新测序芯片区分生物威胁因子和“近邻”物种
Chris R Taitt,Anthony P Malanoski,Baochuan Lin et al.
Chris R Taitt et al.
Timely identification of biothreat organisms from large numbers of clinical or environmental samples in potential outbreak or attack scenario is critical for effective diagnosis and treatment. This study aims to evaluate the potential of re...
Fusobacterium nucleatum enhances invasion of human gingival epithelial and aortic endothelial cells by Porphyromonas gingivalis [0.03%]
核梭杆菌增强牙龈卟啉单胞菌对人牙龈上皮细胞和主动脉内皮细胞的侵袭作用
Atsushi Saito,Satoru Inagaki,Ryuta Kimizuka et al.
Atsushi Saito et al.
Invasion by Porphyromonas gingivalis has been proposed as a possible mechanism of pathogenesis in periodontal and cardiovascular diseases. Porphyromonas gingivalis have direct access to the systemic circulation and endothelium in periodonti...
Dexamethasone modulates Salmonella enterica serovar Typhimurium infection in vivo independently of the glucocorticoid-inducible protein annexin-A1 [0.03%]
糖皮质激素DEX通过独立于GIP annexin-A1的机制调节沙门氏菌体内的感染水平
Tomoko Smyth,Sabine Tötemeyer,Sean Haugland et al.
Tomoko Smyth et al.
Salmonella enterica serovar Typhimurium (S. Typhimurium) infection causes an inflammatory response through activation of Toll-like receptor 4 by lipopolysaccharide. Dexamethasone, a glucocorticoid analogue, suppresses inflammatory responses...
Identification of PER-1 extended-spectrum beta-lactamase producing Pseudomonas aeruginosa clinical isolates of the international clonal complex CC11 from Hungary and Serbia [0.03%]
来自匈牙利和塞尔维亚的国际克隆复合物CC11耐碳青霉烯类抗生素铜绿假单胞菌临床分离株中PER-1扩谱β-内酰胺酶的鉴定
Balázs Libisch,Laurent Poirel,Zorica Lepsanovic et al.
Balázs Libisch et al.
PER-1 extended-spectrum beta-lactamase-producing Pseudomonas aeruginosa clinical isolates from Budapest, Hungary, and Belgrade, Serbia, were characterized by molecular methods. Two PER-1-positive isolates were recovered from sporadic cases ...
Characterization of the cattle serum antibody responses against TEM beta-lactamase and the nonimmunogenic Escherichia coli heat-stable enterotoxin (STaI) [0.03%]
牛血清抗体应答特性对抗菌药物TEM内酰胺酶和非免疫原性大肠杆菌热稳定肠毒素(STaⅠ)的影响
Astrid Zervosen,Claude Saegerman,Ingrid Antoniotti et al.
Astrid Zervosen et al.
In order to test the use of a subunit recombinant vaccine for its capacity to induce antibodies against the nonimmunogenic heat-stable enterotoxin STa from Escherichia coli and the TEM-1 beta-lactamase, cattle were immunized with a hybrid p...
Neutrophil elastase and syndecan shedding contribute to antithrombin depletion in murine anthrax [0.03%]
鼠类吸入型炭疽病中中性粒细胞蛋白酶对抗凝血蛋白抗凝血酶的损伤作用
Myung-Chul Chung,Shelley C Jorgensen,Taissia G Popova et al.
Myung-Chul Chung et al.
Bacillus anthracis infection is associated with severe hemostatic disturbances but their roles and contribution to fatality remain incompletely characterized. We undertook analyses of circulating antithrombin levels during the course of inf...
Secreted dipeptidyl peptidases as potential virulence factors for Microsporum canis [0.03%]
分泌的二肽基肽酶作为Microsporum canis潜在的毒力因子
Sandy Vermout,Aline Baldo,Jérémy Tabart et al.
Sandy Vermout et al.
Dermatophytoses caused by Microsporum canis are frequently encountered in cats and dogs; they are highly contagious and readily transmissible to humans. In this study, two single genes, respectively coding for dipeptidyl peptidases IV and V...
Idiopathic CD4 lymphocytopenia and opportunistic infection--an update [0.03%]
特发性CD4淋巴细胞减少症与机会感染的再评估
Ling Luo,TaiSheng Li
Ling Luo
A severe CD4 T-cell depletion predisposes humans to opportunistic infections. In recent years, reports of cases of opportunistic infections caused by CD4 T-cell depletion without HIV infection have been accumulating. Such cases, termed idio...