The high-affinity phosphate transporter Pst is a virulence factor for Proteus mirabilis during complicated urinary tract infection [0.03%]
高亲和力磷酸盐转运蛋白Pst是普罗威登菌属在复杂尿路感染期间的致病因子
Sandra M Jacobsen,Mary C Lane,Jean M Harro et al.
Sandra M Jacobsen et al.
Proteus mirabilis is a ubiquitous bacterium associated with complicated urinary tract infection (UTI). Mutagenesis studies of the wild-type strain HI4320 in the CBA mouse model of ascending UTIs have identified attenuated mutants with trans...
Effect of tumor necrosis factor-alpha on intracellular Staphylococcus aureus in vascular endothelial cells [0.03%]
肿瘤坏死因子-α对血管内皮细胞胞内金黄色葡萄球菌的影响
Wan Beom Park,Jae Hoon Lee,Jae Hyun Jeon et al.
Wan Beom Park et al.
Although tumor necrosis factor-alpha (TNF-alpha) is an important host factor against intracellular bacteria, little is known about the effect of TNF-alpha on the persistence of intracellular Staphylococcus aureus in vascular endothelial cel...
Mycoplasma genitalium-derived lipid-associated membrane proteins induce activation of MAPKs, NF-kappaB and AP-1 in THP-1 cells [0.03%]
人单核细胞THP-1中衣原体解脲亚种脂质相关膜蛋白诱导MAPKs、NF-KB和AP-1的活化
Xiaoxing You,Yimou Wu,Yanhua Zeng et al.
Xiaoxing You et al.
Mycoplasma genitalium lipid-associated membrane proteins (LAMPg) can induce human monocytic cell line THP-1 to produce proinflammatory cytokines, including tumor necrosis factor-alpha (TNF-alpha), IL-1beta and IL-6, as demonstrated by an en...
Genetic detoxification of an aroA Salmonella enterica serovar Typhimurium vaccine strain does not compromise protection against virulent Salmonella and enhances the immune responses towards a protective malarial antigen [0.03%]
遗传脱毒对伤寒沙门氏菌疫苗株aroA不产生影响，并增强针对保护疟疾抗原的免疫反应
Nicola D McKelvie,Shahid A Khan,Michail H Karavolos et al.
Nicola D McKelvie et al.
Live Salmonella vaccines are limited in use by the inherent toxicity of the lipopolysaccharide. The waaN gene encodes a myristyl transferase required for the secondary acylation of lipid A in lipopolysaccharide. A waaN mutant exhibits reduc...
Effects of possible endocrine disruptors on MyD88-independent TLR4 signaling [0.03%]
可能的内分泌干扰物对MyD88非依赖TLR4信号的影响
Takahiro Ohnishi,Tomohisa Yoshida,Arisa Igarashi et al.
Takahiro Ohnishi et al.
Endocrine disrupting chemicals (EDCs) may potentially worsen infectious diseases because EDCs disturb human immune function by interfering with endocrine balance. To evaluate the influence of EDCs on the innate immune function of macrophage...
Active immunization of hamsters against Clostridium difficile infection using surface-layer protein [0.03%]
利用表面粘附层蛋白对仓鼠进行抗难辨梭菌感染的免疫接种
Déirdre B Ní Eidhin,Julie B O&#x;Brien,Matthew S McCabe et al.
Déirdre B Ní Eidhin et al.
Clostridium difficile is the leading cause of infectious antibiotic-associated diarrhoea, particularly among the elderly. Its surface-layer protein (SLP) was tested as a vaccine component in a series of immunization and challenge experiment...
An epidemic of plasmids? Dissemination of extended-spectrum cephalosporinases among Salmonella and other Enterobacteriaceae [0.03%]
质粒流行病？广泛谱头孢菌素酶在沙门氏菌和其他肠杆菌中的传播
Lin-Hui Su,Chishih Chu,Axel Cloeckaert et al.
Lin-Hui Su et al.
CTX-M- and AmpC-type beta-lactamases comprise the two most rapidly growing populations among the extended-spectrum cephalosporinases. The evolution and dissemination of resistance genes encoding these enzymes occur mostly through the transm...
Persistence of Legionella in hospital water supplies and nosocomial Legionnaires' disease [0.03%]
医院供水系统中军团菌的持久性与医源性军团病的关系
Marian Garcia-Nuñez,Nieves Sopena,Sonia Ragull et al.
Marian Garcia-Nuñez et al.
The molecular epidemiology of clinical and environmental Legionella species isolates was studied in seven hospitals from 1989 to 2006. The number of environmental pulsed field gel electrophoresis (PFGE) patterns ranged from one to nine acco...
M-cells: origin, morphology and role in mucosal immunity and microbial pathogenesis [0.03%]
M细胞：起源、形态和黏膜免疫及微生物发病机制中的作用
Sinead C Corr,Cormac C G M Gahan,Colin Hill
Sinead C Corr
M-cells are specialized cells found in the follicle-associated epithelium of intestinal Peyer's patches of gut-associated lymphoid tissue and in isolated lymphoid follicles, appendix and in mucosal-associated lymphoid tissue sites outside t...
Biological activities from extracts of endophytic fungi isolated from Viguiera arenaria and Tithonia diversifolia [0.03%]
来自Viguiera arenaria和Tithonia diversifolia内生真菌的提取物的生物活性研究
Denise O Guimarães,Warley S Borges,Cristina Y Kawano et al.
Denise O Guimarães et al.
A total of 39 endophytic fungi have been isolated from Viguiera arenaria and Tithonia diversifolia, both collected in São Paulo State, Brazil. The isolates were identified based on their ribosomal DNA sequences. The ethyl acetate (EtOAc) e...