Identification of Salmonella SPI-2 secretion system components required for SpvB-mediated cytotoxicity in macrophages and virulence in mice [0.03%]
鉴定出参与沙门氏菌SPI-2分泌系统中调控SpvB毒力的元件
Sara H Browne,Patricia Hasegawa,Sharon Okamoto et al.
Sara H Browne et al.
The Salmonella SpvB protein possesses ADP-ribosyl transferase activity. SpvB, acting as an intracellular toxin, covalently modifies monomeric actin, leading to loss of F-actin filaments in Salmonella-infected human macrophages. Using define...
Development of a cytolethal distending toxin (cdt) gene-based species-specific multiplex PCR assay for the detection and identification of Campylobacter jejuni, Campylobacter coli and Campylobacter fetus [0.03%]
一种用于检测和鉴定空肠弯曲菌、大肠弯曲菌和胎儿弯曲菌的基于细胞致死肿胀毒素（cdt）基因的多重PCR测定法的发展
Masahiro Asakura,Worada Samosornsuk,Atsushi Hinenoya et al.
Masahiro Asakura et al.
A cytolethal distending toxin (cdt) gene-based species-specific multiplex PCR assay for the detection of cdtA, cdtB or cdtC gene of Campylobacter jejuni, Campylobacter coli or Campylobacter fetus, respectively, was developed and evaluated w...
Comparative prevalence of plasma human herpesvirus 8 DNA in sexual contact and intravenous injection routes of HIV transmission [0.03%]
不同途径感染HIV者血浆人疱疹病毒8DNA的流行病学调查及比较研究
Cheng-Wen Lin,Chun-Pin Chang,Fang-Yang Wu et al.
Cheng-Wen Lin et al.
Detection of plasma human herpesvirus (HHV)-8 DNA correlates with antibodies to lytic HHV-8 antigens, being predictive of Kaposi's sarcoma in HIV-infected patients. We show that the prevalence of plasma HHV-8 DNA was 10.6% for HIV infection...
Serotyping of Dutch Staphylococcus aureus strains from carriage and infection [0.03%]
荷兰携带和感染的金黄色葡萄球菌的血清型分布
Damian C Melles,Kimberly L Taylor,Ali I Fattom et al.
Damian C Melles et al.
International epidemiological studies have shown that clinical isolates of Staphylococcus aureus are usually capsulated with either type 5 or 8 capsular polysaccharides (CPs). Because all noncapsulated strains were found to be cross-reactiv...
Bing-Mu Hsu,Chien-Hsien Chen,Min-Tao Wan
Bing-Mu Hsu
Enteroviruses can be introduced into the water environment as a result of human activity. Contaminations within hot tubs, spas and public baths are also possible. We investigated the distribution of enteroviruses at six hot spring recreatio...
Staphylococcus aureus infection triggers production of neutralizing, V8 protease-specific antibodies [0.03%]
金黄色葡萄球菌感染引发中和V8蛋白酶的特异性抗体产生
Ann-Marie Calander,Grzegorz Dubin,Jan Potempa et al.
Ann-Marie Calander et al.
Staphylococcus aureus infection triggers polyclonal B-cell activation. It was sought to further characterize the hypergammaglobulinemia seen in Staphylococcus aureus infection, focusing on the significance of protease-specific B-cell respon...
Nicotine involved in periodontal disease through influence on cytokine levels [0.03%]
尼古丁通过影响细胞因子水平参与牙周病
Asako Makino,Satoru Yamada,Katsuji Okuda et al.
Asako Makino et al.
Periodontal disease, for which smoking is a known risk factor, is infectious, and is associated with oral biofilm. Cytokines mediate and regulate immune and inflammatory responses. Lipopolysaccharide produced by periodontopathic bacteria pl...
Antimicrobial and immunoregulatory effects mediated by human lung cells: role of IFN-gamma-induced tryptophan degradation [0.03%]
人肺细胞介导的抗菌和免疫调节作用：IFN-γ诱导的色氨酸分解的作用
Kathrin Heseler,Katrin Spekker,Silvia K Schmidt et al.
Kathrin Heseler et al.
Pneumonia caused by bacterial, viral and parasitic pathogens is one of the most common clinical problems facing primary and secondary care physicians. Staphylococcus aureus is a common cause of lung abscesses in humans and, in immunocomprom...
Zoonotic cryptosporidiosis [0.03%]
人畜共患隐孢子虫病
Lihua Xiao,Yaoyu Feng
Lihua Xiao
The widespread usages of molecular epidemiological tools have improved the understanding of cryptosporidiosis transmission. Much attention on zoonotic cryptosporidiosis is centered on Cryptosporidium parvum. Results of genotype surveys indi...
Nasal immunization with the mixture of PA63, LF, and a PGA conjugate induced strong antibody responses against all three antigens [0.03%]
PA63、LF和PGA结合物混合鼻内免疫可诱导所有三种抗原的强抗体反应
Brian R Sloat,Dalia S Shaker,Uyen M Le et al.
Brian R Sloat et al.
A new generation anthrax vaccine is expected to target not only the anthrax protective antigen (PA) protein, but also other virulent factors of Bacillus anthracis. It is also expected to be amenable for rapid mass immunization of a large nu...