Cyclic AMP-regulated GABA release at inhibitory synapses in rat cerebellar slices [0.03%]
大鼠小脑片抑制性突触上环AMP调节的GABA释放作用
A Marty,M Glitsch,S Kondo et al.
A Marty et al.
We have investigated the effects of agents interfering with the cAMP pathway on the rate of miniature IPSCs in cerebellar slices. Noradrenaline and group II glutamate metabotropic receptor agonists respectively enhance and reduce the rate o...
Three-dimensional synaptic distributions influence neural processing through the resource consumption principle [0.03%]
三维突触分布通过资源消耗原则影响神经处理
C Person,D M Egelman,R D King et al.
C Person et al.
Nitric oxide acts as a retrograde messenger during long-term potentiation in cultured hippocampal neurons [0.03%]
一氧化氮在培养海马神经元长时程增强中的逆行信使作用
O Arancio,V Lev-Ram,R Y Tsien et al.
O Arancio et al.
We examined long-term potentiation (LTP) at synapses between hippocampal neurons in dissociated cell culture following presynaptic, postsynaptic, or extracellular application of a nitric oxide (NO) scavenger, an inhibitor of NO synthase, an...
Different threshold levels of postsynaptic [Ca2+]i have to be reached to induce LTP and LTD in neocortical pyramidal cells [0.03%]
不同水平的突触后[CA2+]i阈值诱导新皮层锥体细胞的长时程增强和长时程抑制
C Hansel,A Artola,W Singer
C Hansel
Changes in [Ca2+]i were measured in layer II-III pyramid cells of the rat visual cortex slices during application of either LTP or LTD inducing stimulation protocols. At dendritic sites activated by the stimulated afferents [Ca2+]i reached ...
Long-term potentiation as a mechanism of functional synapse induction in the developing hippocampus [0.03%]
长期增强作为发育海马功能突触诱发的机制
G M Durand,A Konnerth
G M Durand
During the first 2 days of postnatal development, CA1 hippocampal glutamatergic synaptic transmission is based almost exclusively on NMDA receptors and is non-functional at resting potential. Within the following days an increasing number o...
Evidence that presynaptic changes are involved in the expression of LTP and LTD of NMDA receptor-mediated EPSCs in area CA1 of the hippocampus [0.03%]
长期增强和长期抑制的表达与海马CA1区NMDAR介导的EPSCs的突触前改变有关的确切证据
K A Clark,G L Collingridge
K A Clark
Plasticity of NMDA receptor-mediated synaptic transmission was studied in the CA1 region of the hippocampus utilising whole cell patch-clamp recording techniques. LTP was associated with a decrease in CV whereas LTD was accompanied by an in...
Synaptic and non-synaptic plasticity between individual pyramidal cells in the rat hippocampus in vitro [0.03%]
大鼠海马皮层锥体细胞的突触和非突触可塑性研究
D Debanne,B H Gähwiler,S M Thompson
D Debanne
We report here two forms of activity-dependent plasticity of the transfer of neuronal information between pairs of monosynaptically coupled pyramidal cells. In a first part, we discuss the induction of long-term bidirectional changes in exc...
Induction of heterosynaptic and homosynaptic LTD in hippocampal sub-regions in vivo [0.03%]
在海马亚区诱导异突触和同突触长时程抑制造钟
W C Abraham
W C Abraham
Establishing the conditions under which long-term depression (LTD) an be induced in vitro remains an important empirical issue. While heterosynaptic LTD is readily elicited in the hippocampus in vivo, the induction of homosynaptic LTD has b...
J T Isaac,S H Oliet,G O Hjelmstad et al.
J T Isaac et al.
We have taken a number of different experimental approaches to address whether long-term potentiation (LTP) in hippocampal CA1 pyramidal cells is due primarily to presynaptic or postsynaptic modifications. Examination of miniature EPSCs or ...