Understanding the Role of Polyunsaturated Fatty Acids in the Development and Prevention of Cancer [0.03%]
多不饱和脂肪酸在癌症发展和预防中的作用研究
Samina Akbar,Abdur Rahman,Nazir Ahmad et al.
Samina Akbar et al.
Polyunsaturated fatty acids (PUFAs), notably omega-3 (n-3) and omega-6 (n-6), have received much attention owing to their multifaceted effects not only in the management of diverse pathological conditions but also in the maintenance of over...
Metabolic Carcinogenesis [0.03%]
代谢致癌作用
Mahwish Ali,Syeda Mehpara Farhat,Abdul Haleem
Mahwish Ali
Several types of environmental, chemical and metabolic carcinogens exist both exogenously and endogenously. Humans are daily exposed to aforementioned carcinogens through various sources such as through water, air and food or through metabo...
Hanadi Talal Ahmedah,Haneen Adel Basheer,Inas Almazari et al.
Hanadi Talal Ahmedah et al.
By the beginning of the year 2021, the estimated number of new cancer cases worldwide was about 19.3 million and there were 10.0 million cancer-related deaths. Cancer is one of the deadliest diseases worldwide that can be attributed to gene...
The Global Landscape on the Access to Cancer Medicines for Breast Cancer: The ONCOLLEGE Experience [0.03%]
乳腺癌抗癌药物的全球可及性现状——ONCOLLEGE的经验
Csongor György Lengyel,Baker Shalal Habeeb,Sara Cecilia Altuna et al.
Csongor György Lengyel et al.
There is a growing global debate over barriers affecting the timely access to innovative anticancer therapies. Access to medicines is often traced back to the issue of costs: however, more commonly, the distance between valuable innovative ...
Next-Generation Sequencing for Advanced Breast Cancer: What the Way to Go? [0.03%]
下一代测序在进展期乳腺癌中的应用：发展方向？
Dario Trapani,Edoardo Crimini,José Sandoval et al.
Dario Trapani et al.
The rapid implementation of precision medicine tools in diagnosing and treating breast cancer (BC) has widened the potential therapeutic options for patients. The applications of gene sequencing, including next-generation gene sequencing (N...
Paola Zagami,Eleonora Nicolò,Chiara Corti et al.
Paola Zagami et al.
Cancer and cardiovascular disease are the two major causes of morbidity and mortality in worldwide. Discovering new therapeutic agents for the management of breast cancer (BC) has increased the numbers of cancer survivors but with the risk ...
Breast Cancer Brain Metastases: Achilles' Heel in Breast Cancer Patients' Care [0.03%]
乳腺癌脑转移：乳腺癌患者治疗中的难点
Emanuela Ferraro,Andrew D Seidman
Emanuela Ferraro
Brain metastases (BM) significantly affect the prognosis as well as the quality of life of breast cancer (BC) patients. Although advancements in neurosurgical and radiotherapy techniques improve local control and symptom management, BM rema...
Innovative Therapeutic Approaches for Patients with HER2-Positive Breast Cancer [0.03%]
HER2阳性乳腺癌患者的创新治疗方法
Beatrice Taurelli Salimbeni,Emanuela Ferraro,Luca Boscolo Bielo et al.
Beatrice Taurelli Salimbeni et al.
Overexpression of human epidermal growth factor receptor 2 (HER2), a transmembrane tyrosine kinase receptor, has been described in about 15-20% of breast cancer (BC) and is associated with poor outcomes. Trastuzumab is the first anti-HER2 m...
Mechanisms of Endocrine Resistance in Hormone Receptor-Positive Breast Cancer [0.03%]
激素受体阳性乳腺癌内分泌耐药的机制
Antonio Marra,Dario Trapani,Emanuela Ferraro et al.
Antonio Marra et al.
Hormone receptor-positive (HR+) breast cancer (BC) accounts for approximately 70% of all breast invasive tumors. Endocrine therapy (ET) represents the standard treatment for HR + BC. Most patients, however, eventually develop resistance to ...
Fast Mimicking Diets and Other Innovative Nutritional Interventions to Treat Patients with Breast Cancer [0.03%]
快速模拟饮食和其他创新营养干预措施在乳腺癌患者中的应用
Federica Giugliano,Laura Boldrini,Jacopo Uliano et al.
Federica Giugliano et al.
The impact of nutritional patterns on the risk of breast cancer (BC) is well investigated in the oncology literature, including the type of diets and caloric intake. While obesity and elevated body mass index are well-reported critical risk...