Hariharan Thirumalai Vengateswaran,Mohammad Habeeb,Huay Woon You et al.
Hariharan Thirumalai Vengateswaran et al.
Targeting metabolic pathways provides novel therapeutic prospects as metabolic reprogramming is becoming more widely recognized as a characteristic of a variety of disorders. Despite preclinical research and clinical trials demonstrating th...
Ayush Madan,Subhajit Mandal,Soukat Chandra et al.
Ayush Madan et al.
Tools for studying cancer metabolism include mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy for metabolomics, metabolic imaging (PET, MRI, MRS) for in vivo analysis, and metabolic flux analysis (MFA) with stable is...
Cancer and Immune Cells: A Metabolic Battle in the Tumor Microenvironment [0.03%]
肿瘤微环境中癌细胞与免疫细胞的代谢竞争关系
Sam Pournezhad,Ramyar Azar,Farzad Taghizadeh-Hesary
Sam Pournezhad
Immunometabolism has emerged as a critical field that links cellular energy regulation with immune function, including in the context of cancer. The tumor microenvironment (TME) is characterized by hypoxia, acidosis, and nutrient competitio...
Hamid Tanzadehpanah,Ali Ahmadizad Firouzjaei,Nafiseh Izadi et al.
Hamid Tanzadehpanah et al.
Insight into the metabolic reprogramming of cancer cells provides not only an understanding of the biology of the tumor but also novel biomarkers for diagnosis, prognosis, and therapy response monitoring. Cellular differentiation of tumors ...
Bhabani Shankar Nayak,Bangmayee Dash,Sisir Nandi et al.
Bhabani Shankar Nayak et al.
Cancer cells show different abnormal metabolic pathways that promote their development and viability. A novel therapeutic strategy has emerged for the treatment of cancer by inhibiting major metabolic pathways, such as the glycolysis pathwa...
Gaurav Ranjan,Srijani Dasgupta,Uttam Kumar Mishra et al.
Gaurav Ranjan et al.
Cancer stem cells (CSCs) are a subset of tumor cells that exhibit self-renewal, differentiation potential, and resistance to conventional therapies. One of the characteristic traits of CSCs is their metabolic flexibility, with the ability t...
Chinmay Das,Somya Ranjan Dash,Biswajit Das et al.
Chinmay Das et al.
The tumor microenvironment (TME) is a dynamic network of diverse cellular and noncellular components that interact with malignant cells to influence cancer progression, immune evasion, metastasis, and the development of therapeutic resistan...
Pedram Fadavi,Farzad Taghizadeh-Hesary
Pedram Fadavi
Cancer metabolism has long been interpreted through Otto Warburg's original observation that malignant cells favor aerobic glycolysis due to defective mitochondria. Although foundational, this view is now recognized as incomplete. Contempor...
Nahid Nafissi,Pedram Fadavi,Farzad Taghizadeh-Hesary
Nahid Nafissi
Oxidative stress is a pivotal regulator of cancer biology, influencing both the initiation and progression of malignancy. Oxidative stress results from an imbalance between the generation of reactive oxygen species (ROS) and the ability of ...
Mirunalini Gobinath,Pratik Phalke,Parikshit Roychowdhury et al.
Mirunalini Gobinath et al.
Lipid metabolism is important for processes, such as tumor progression, because cancer cells undergo metabolic changes that assist in maintaining their growth, survival, and metastasis. During the development, cancer cells usually adapt to ...