Thrombosis in the Philadelphia Chromosome-Negative Myeloproliferative Neoplasms [0.03%]
费城染色体阴性骨髓增生性肿瘤的血栓形成事件
Kamya Sankar,Brady L Stein,Raajit K Rampal
Kamya Sankar
The myeloproliferative neoplasms (MPNs) are clonal stem cell-derived diseases. This chapter focuses on the subcategory of Philadelphia (Ph) chromosome-negative classical MPNs, polycythemia vera (PV), essential thrombocythemia (ET), primary ...
Mari R Thomas,Marie Scully
Mari R Thomas
Thrombotic microangiopathy (TMA) is a syndrome involving fragmentation haemolysis, thrombocytopenia, and thrombosis. A range of disorders including cancer may have TMA as a clinical manifestation. TMA in cancer may be caused by several mech...
Jodi V Mones,Gerald Soff
Jodi V Mones
Chemotherapy-induced thrombocytopenia (CIT) is a frequent complication of cancer therapy, leading to increased risk of bleeding, when the thrombocytopenia is severe (
Etiology and Management of Upper-Extremity Catheter-Related Thrombosis in Cancer Patients [0.03%]
癌症患者的上肢导管相关性血栓形成的病因及处理措施
Anita Rajasekhar,Michael B Streiff
Anita Rajasekhar
Central venous access devices are a critical instrument in the treatment and supportive care delivery for oncology patients. Catheter-related thrombosis (CRT) is a common complication of central venous access devices in oncology patients. R...
Treatment of Venous Thromboembolism in Cancer. Historical Perspective and Evolving Role of the Direct Oral Anticoagulants [0.03%]
癌症患者的静脉血栓栓塞治疗：历史回顾和直接口服抗凝剂的演变作用
Marc Carrier,Gerald Soff,Grégoire Le Gal
Marc Carrier
The management of cancer-associated thrombosis (CAT) is complex, and treatment strategies have been evolving over the past 15 years. It is well recognized that oral vitamin K antagonists are difficult to use in cancer patients, with higher ...
M D Debbie Jiang,M D Alfred Ian Lee
M D Debbie Jiang
Cancer patients have an increased risk of thrombosis. The development of cancer thrombosis is dependent on a number of factors including cancer type, stage, various biologic markers, and the use of central venous catheters. In addition, can...
Anjlee Mahajan,Ted Wun
Anjlee Mahajan
Venous thromboembolism is known to be associated with an increase in morbidity and mortality in patients with malignancy. Predictive laboratory biomarkers of venous thromboembolism (VTE) have long been sought after to improve outcomes and h...
Risk of Thrombosis in Cancer: Clinical Factors and Role of Primary Prophylaxis [0.03%]
癌症血栓风险的临床因素及一级预防的作用
Joanna Roopkumar,Alok A Khorana
Joanna Roopkumar
Cancer and its treatments are commonly complicated by venous thromboembolism (VTE), but there is a substantial variation in risk between individual cancer patients. The risk of VTE in cancer patients is influenced by multiple risk factors i...
Aime T Franco,Jerry Ware
Aime T Franco
For over 100 years, a link has been recognized between thrombosis and cancer. However, whether this was a causal or correlational relationship was debated. It is now well established that cancer and thrombosis are mechanistically related in...
Anna Falanga,Francesca Schieppati,Laura Russo
Anna Falanga
Thrombosis is a major cause of morbidity and mortality in cancer patients. The pathogenesis of blood coagulation activation in oncological patients is complex and involves both clinical and biological factors. Abnormalities in one or more c...