Eleonora Timperi,Elena Vissio,Caterina Marchiò et al.
Eleonora Timperi et al.
In this chapter, we summarize the latest findings in the field of immuno-oncology of women cancers, particularly ovarian and breast tumors. We describe the relationship between immune parameters and clinical outcomes by evaluating the contr...
The Role of the Immune Infiltrate in Distinct Cancer Types and Its Clinical Implications : Lymphocytic Infiltration in Colorectal Cancer [0.03%]
肿瘤免疫微环境的多样性及其临床意义：结直肠癌中的淋巴细胞浸润
Jérôme Galon,Daniela Bruni
Jérôme Galon
Colorectal cancer (CRC) represents a major public health challenges, with one of the highest incidences worldwide. The two affected anatomical sites in CRC, i.e. the colon and the rectum, share important underlying features, but often diffe...
Sara I Pai,Alessandra Cesano,Francesco M Marincola
Sara I Pai
Checkpoint inhibitor therapy (CIT) has revolutionized cancer treatment but it has also reached a standstill when an absent dialog between cancer and immune cells makes it irrelevant. This occurs with high prevalence in the context of "immun...
Davide Bedognetti,Alessandra Cesano,Francesco M Marincola et al.
Davide Bedognetti et al.
The development of cancer results from the evolutionary balance between the proliferating aptitude of cancer cells and the response of the host's tissues. Some cancers are characterized by genetic instability dependent upon impaired DNA rep...
Han,Lotze
Han
The adaptive immune response is a 500-million-year-old (the "Big Bang" of Immunology) collective set of rearranged and/or selected receptors capable of recognizing soluble and cell surface molecules or shape (B cells, antibody), endogenous ...
Lei Wang,Peter P Lee
Lei Wang
It is increasingly recognized that cancer does not involve only formation of a tumor, but also systemic changes in the host. Alterations in number, spatial relationship, and function of immune cells have been identified in cancer patients' ...
George McNamara,Justin Lucas,John F Beeler et al.
George McNamara et al.
The premise of this book is the importance of the tumor microenvironment (TME). Until recently, most research on and clinical attention to cancer biology, diagnosis, and prognosis were focused on the malignant (or premalignant) cellular com...
Mohammad Haris,Sabah Nisar,Sheema Hashem et al.
Mohammad Haris et al.
Noninvasive imaging of functional and molecular changes in cancer has become an indispensable tool for studying cancer in vivo. Targeting the functional and molecular changes in cancer imaging provides a platform for the in vivo analysis of...
Simon Mantha
Simon Mantha
Cancer can be associated with several distinct coagulation defects which can lead to bleeding complications. The primary hyperfibrinolytic syndrome associated with acute promyelocytic leukemia has been well recognized and is one of the most...
Charlene Mantia,Jeffrey I Zwicker
Charlene Mantia
Venous thromboembolism is commonly diagnosed in patients with primary and secondary brain tumors. Anticoagulation management in the setting of brain tumors is complicated by the high background rate of spontaneous intracranial hemorrhage. U...