Sabba Mehmood,Shaista Aslam,Erum Dilshad et al.
Sabba Mehmood et al.
In past quarter of the century, much has been understood about the genetic variation and abnormal genes that activate cancer in humans. All the cancers somehow possess alterations in the DNA sequence of cancer cell's genome. In present, we ...
Asma Saleem Qazi
Asma Saleem Qazi
Cancer is a complex disease. According to the Globocan survey, 63% deaths are due to cancer. There are some conventional methods that are used to treat cancer. However, certain treatment modalities are under clinical trials still. The succe...
Investigating Novel Genetic Markers for Fluoroquinolone Associated Disorders [0.03%]
氟喹诺酮相关性疾病新型遗传标记物的研究
Andrew Bennett
Andrew Bennett
Fluoroquinolones (FQs) are among the most commonly prescribed class of antibiotics and have regulatory approval to treat anthrax, pneumonia, unitary tract infections, and sinus infection among other uses. ...
Moderna, Pfizer-BioNTech, and Johnson & Johnson/Janssen Post-Covid Vaccine Hematological Adverse Events Including Cerebral Venous Sinus Thrombosis (CVST), Thrombotic Thrombocytopenia (VITT), Blood Clots, Increased Vaginal/Menstrual Bleeding and/or Miscarriage, Stillbirth Delivery, or Premature Birth [0.03%]
莫德纳、辉瑞-生物技术公司和强生/杨森新冠疫苗接种后的血液不良反应事件，包括脑静脉窦血栓（CVST）、血栓性血小板减少症（VITT）、血栓形成、阴道或月经出血增加及流产、死产或早产
Oscar Champigneulle,Charles L Bennett
Oscar Champigneulle
The Centers for Disease Control (CDC) indicated in 2021 that it would monitor for possible post-COVID-19 vaccination coagulopathy adverse events (AEs). ...
Consequences to Patients, Clinicians, and Manufacturers When Very Serious Adverse Drug Reactions Are Identified (1997-2019): A Qualitative Analysis from the Southern Network on Adverse Reactions (SONAR) [0.03%]
当非常严重的药物不良反应被确认时对患者、临床医生和制造商的影响（1997-2019年）：南方网络药物不良反应(SONAR)的定性分析
Courtney R Lubaczewski,Nancy F Olivieri,William R Hrushesky et al.
Courtney R Lubaczewski et al.
Adverse drug/device reactions (ADRs) serious enough to lead to box warnings on drug labels or drug withdrawals occur in about one fifth of all new molecular entities. ...
Investigating Severe Adverse Reactions: Examples of the ANTICIPATE Methodology at Work [0.03%]
严重不良反应的调查：ANTICIPATE方法的应用实例
Charles L Bennett,Shamia Hoque
Charles L Bennett
Severe adverse drug reactions (sADRs) are important causes of morbidity and mortality. The Southern Network on Adverse Drug Reactions (SONAR), a National Cancer Institute-funded pharmacovigilance program, has outlined a novel 9-stop methodo...
Maximum Accuracy Machine Learning Statistical Analysis-A Novel Approach [0.03%]
最大精度机器学习统计分析-一种新颖的方法
Shannon Ugarte,Paul Yarnold,Paul Ray et al.
Shannon Ugarte et al.
Logistic regression is a statistical tool of paramount significance in the field of epidemiology1 and ranks as one of the most frequently published multivariable analyses for designs involving a single binary dependent variable and one or m...
Rituximab-Associated Progressive Multifocal Leukoencephalopathy: A Twenty-Year Update [0.03%]
与利妥昔单抗相关的进行性多灶性白质脑病：20年回顾更新
Charles L Bennett,Bartlett Witherspoon,Kenneth R Carson
Charles L Bennett
Progressive multifocal leukoencephalopathy (PML) is a John-Cunningham virus-related central nervous system that is rarely observed in persons treated with the anti-CD20 monoclonal antibody, rituximab. ...
Was There Something Rotten in Denmark: Nephrogenic System Fibrosis Cases Occurring in Copenhagen [0.03%]
丹麦的腐败：哥本哈根发生的肾源性系统纤维症病发案例
Charles L Bennett,Bartlett Witherspoon,Kenneth R Carson et al.
Charles L Bennett et al.
More than half of all serious adverse drug reactions are identified seven years after FDA approval. One recent and unusual example involves a syndrome initially termed nephrogenic dermatopathic fibrosis, and then called nephrogenic systemic...
Systemic Barriers and Potential Concerns from Reporting Serious Adverse Drug Reactions [0.03%]
严重药物不良反应上报的体制障碍与潜在问题
Matthew A Taylor,Ashley C Godwin,Shamia Hoque et al.
Matthew A Taylor et al.
About 1-10% of all serious adverse drug reactions (sADRs) are reported to the Food and Drug Administration (FDA) ( Moore T, Bennett C. Underreporting of Hemorrhagic and Thrombotic Complications of Pharmaceuticals to the U.S. Food and Drug A...