Brain-Implantable Multifunctional Probe for Simultaneous Detection of Glutamate and GABA Neurotransmitters [0.03%]
一种可脑内植入的检测谷氨酸和γ氨基丁酸神经递质的多功能探针
Nicolaie Moldovan,Iuliu-Ioan Blaga,Sanjeev Billa et al.
Nicolaie Moldovan et al.
Glutamate (GLU) and gamma-aminobutyric acid (GABA) are neurotransmitters (NTs) with an essential role in signal transmission in the brain. Brain disorders, such as epilepsy, Alzheimer's and Parkinson's diseases, and traumatic brain injury c...
High-sensitivity and point-of-care detection of SARS-CoV-2 from nasal and throat swabs by magnetic SERS biosensor [0.03%]
基于磁性SERS生物传感器的鼻咽拭子样本快速高效检测新型冠状病毒(SARS-Cov-2)
Yanyan Li,Chenglong Lin,Yusi Peng et al.
Yanyan Li et al.
The outbreak of COVID-19 caused by SARS-CoV-2 urges the development of rapidly and accurately diagnostic methods. Here, one high-sensitivity and point-of-care detection method based on magnetic SERS biosensor composed of Fe3O4-Au nanocompos...
Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum [0.03%]
人血清中多种病毒变异快速检测的纳米等离子生物传感器
Nikhil Bhalla,Amir Farokh Payam,Alessio Morelli et al.
Nikhil Bhalla et al.
As viruses constantly change due to mutation, variants are expected to emerge demanding development of sensors capable of detecting multiple variants using one single sensor platform. Herein, we report the integration of a synthetic binder ...
Prospects of NIR fluorescent nanosensors for green detection of SARS-CoV-2 [0.03%]
用于绿色检测的SARS-CoV-2近红外荧光纳米传感器前景展望
Dan Li,Zipeng Zhou,Jiachen Sun et al.
Dan Li et al.
The pandemic of the novel coronavirus disease 2019 (COVID-19) is continuously causing hazards for the world. Effective detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can relieve the impact, but various toxic chemi...
CRISPR-Cas13a cascade-based viral RNA assay for detecting SARS-CoV-2 and its mutations in clinical samples [0.03%]
基于CRISPR-Cas13a级联的SARS-CoV-2及其突变体临床样本检测体系
Yuxi Wang,Ting Xue,Minjin Wang et al.
Yuxi Wang et al.
SARS-CoV-2 is one of the greatest threats to global human health. Point-of-care diagnostic tools for SARS-CoV-2 could facilitate rapid therapeutic intervention and mitigate transmission. In this work, we report CRISPR-Cas13a cascade-based v...
Generation of Dual functional Nanobody-Nanoluciferase Fusion and its potential in Bioluminescence Enzyme Immunoassay for trace Glypican-3 in Serum [0.03%]
双功能纳米抗体-纳米荧光素酶融合蛋白的构建及其在微量Glypican-3生物发光免疫测定中的应用研究
Sheng Yu,Zhenfeng Li,Jingzhang Li et al.
Sheng Yu et al.
Glypican-3 (GPC3) is a serological biomarker for the diagnosis of Hepatocellular carcinoma (HCC), but it is a challenging task to develop a bioassay for determination of the trace GPC3 in serum. In this study, Bioluminescense immunoassay ba...
Silver nanotriangle array based LSPR sensor for rapid coronavirus detection [0.03%]
基于LSPR传感器的银纳米三角阵列快速冠状病毒检测方法研究
Yanjun Yang,Jackelyn Murray,James Haverstick et al.
Yanjun Yang et al.
A rapid, portable, and cost-effective method to detect the infection of SARS-CoV-2 is fundamental toward mitigating the current COVID-19 pandemic. Herein, a human angiotensin-converting enzyme 2 protein (ACE2) functionalized silver nanotria...
Controlled, partially exfoliated, self-supported functionalized flexible graphitic carbon foil for ultrasensitive detection of SARS-CoV-2 spike protein [0.03%]
用于超灵敏检测SARS-CoV-2刺突蛋白的可控部分剥离的功能性柔性石墨碳膜
Muhammad Adeel,Kanwal Asif,Vincenzo Canzonieri et al.
Muhammad Adeel et al.
This paper reports on an ultrasensitive and label-free electrochemical immunosensor for monitoring the SARS-CoV-2 spike protein (SARS-CoV-2 SP). A self-supported electrode, which can simultaneously serve as an antibody immobilization matrix...
Multiplex Sensing of Complex Mixtures by Machine Vision Analysis of TLC-SERS Images [0.03%]
基于TLC-SERS图像机器视觉分析的复杂混合物多重传感技术
Xingwei Hou,Kundan Sivashanmugan,Yong Zhao et al.
Xingwei Hou et al.
Thin layer chromatography in tandem with surface-enhanced Raman scattering (TLC-SERS) has demonstrated tremendous potentials as a new analytical chemistry tool to detect a wide range of substances from real-world samples. However, it still ...
A novel enhanced substrate for label-free detection of SARS-CoV-2 based on surface-enhanced Raman scattering [0.03%]
一种基于表面增强拉曼散射的SARS-CoV-2无标记检测的新基底
Zhe Zhang,Shen Jiang,Xiaotong Wang et al.
Zhe Zhang et al.
Accurate and sensitive detection of SARS-CoV-2 is an effective strategy for preventing the COVID-19 pandemic in the current absence of specific drug therapy. This study presents a novel enhanced substrate for label-free detection of respira...