Extended Foreign Body Mitigation for Glucose Biosensors via Tertiary S-nitrosothiol-modified Mesoporous Silica Nanoparticle-doped Sensor Membranes [0.03%]
通过三级S-硝基硫醇修饰的介孔硅纳米粒子掺杂传感器膜进行血糖生物传感器的远端异物缓解
Mikaylin E Nogler,Rajnish Kumar,Luc Morgan et al.
Mikaylin E Nogler et al.
The foreign body response (FBR) limits continuous glucose monitor longevity to 10 - 15 d because of chronic inflammation and collagen capsule formation surrounding the implant site. Nitric oxide (NO), a multifunctional bioactive molecule, h...
Magnetic bead electrochemical sandwich assay (MBESA) for the inflammatory cytokine interleukin-1β in fetal membrane on-a-chip studies and placental macrophages [0.03%]
基于磁珠的电化学夹心法（MBESA）在胎膜芯片研究和胎盘巨噬细胞中用于炎症细胞因子白介素-1β检测
Hannah A Richards,Olivia E Owens,Jacklyn E Martin et al.
Hannah A Richards et al.
Preterm birth (PTB), triggered by preterm premature rupture of membranes (PPROM), remains a global health challenge, often linked to infections like chorioamnionitis. Existing biomarker detection methods, such as ELI-SAs, are limited by tim...
Rapid and accessible tumor necrosis factor alpha detection using digital nanoparticle sensors towards point-of-care cytokine monitoring [0.03%]
基于数字纳米颗粒传感器的肿瘤坏死因子α快速无标记检测用于床边细胞因子监测
Maziyar Kalateh Mohammadi,Mohammad Altarfa,Seyedsina Mirjalili et al.
Maziyar Kalateh Mohammadi et al.
Cytokine monitoring is essential for understanding immune response and evaluating therapeutic outcomes in inflammatory and autoimmune diseases. Here, Tumor Necrosis Factor-alpha (TNF-α) is employed as an exemplary cytokine marker to demons...
Optical imaging of microfluidic integrated smart hydrogels for research and sensing applications [0.03%]
用于研究和传感应用的微流控集成智能水凝胶光学成像
Saeed Boroomand,Simon Binder,Moritz Leber et al.
Saeed Boroomand et al.
Smart hydrogels are a versatile class of materials that are attractive for biomedical sensor applications due to their potential biocompatibility and stimuli-responsiveness. However, the integration of these hydrogels into sensors requires ...
A Novel Peptide Multimer for Enhanced Imaging and Multivalent Detection of Hepatocellular Carcinoma [0.03%]
一种用于增强成像和多价检测肝细胞癌的新型肽聚体
Shuo Feng,Xiaoli Wu,Eun-Young K Choi et al.
Shuo Feng et al.
The global incidence of hepatocellular carcinoma (HCC) is rising steadily, yet early detection methods remain a major clinical challenge due to genetic heterogeneity and variable target expression in these tumors. Conventional imaging appro...
Adem Ozcelik,Simona Clement,Aishwarya Patel et al.
Adem Ozcelik et al.
The need for automated analytical devices capable of handling low-volume samples remains a major challenge in medical diagnostics, biomedical research, and environmental studies. Although microfluidic systems have shown promise, their broad...
Noninvasive Monitoring of Skin pH Changes Induced by Microneedle Electroporation [0.03%]
微针电穿孔引起的皮肤pH变化的无创监测
Dengning Xia,Huan Yu,Song Li et al.
Dengning Xia et al.
The pH of the skin surface plays a critical role in maintaining epidermal homeostasis and barrier function. Microneedle electroporation represents a pivotal advancement in transdermal drug and gene delivery; however, the concomitant electro...
Portable hepatitis C virus RNA extraction and stabilization using low-cost lab-on-a-chip style components with shelf stable reagents [0.03%]
使用低成本芯片实验室式组件和常温稳定的试剂进行便携式的丙型肝炎病毒RNA提取及稳定化处理
Sarah Hernandez,Dhruv Miglani,Jayden Kimbro et al.
Sarah Hernandez et al.
Molecular tests offer a powerful approach to diagnosing numerous diseases and, due to advances in lab-on-a-chip technologies, have the potential to be used in the field and at the bedside. However, there is still a need for portable technol...
A Dual-Function Micropatterned Gold Platform for Cell Patterning and Optical Imaging Applications [0.03%]
用于细胞构图和光学成像应用的双重功能微图案金平台
Swati Tanwar,Lintong Wu,Matthew Pittman et al.
Swati Tanwar et al.
How can we reliably study cellular interactions and molecular responses in well-defined microenvironments while maintaining compatibility with high-sensitivity optical imaging techniques? Addressing this question is critical for understandi...
Portable histone assay technology (PHAST) for the sample-to-answer detection of circulating histones in whole blood [0.03%]
一种便携式组蛋白检测技术(PHAST)，用于全血中循环组蛋白的样品到答案检测
Rachel L Warren,John R Rzasa,Zehra F Syeda et al.
Rachel L Warren et al.
Circulating histones are a potential biomarker for organ failure, organ transplant rejection, and sepsis. There is a need for point-of-care detection of histones in patient samples to enable diagnostics in the emergency department (sepsis),...