Multi-wavelength Spatial LED illumination based detector for in vitro detection of Botulinum Neurotoxin A Activity [0.03%]
基于多波长空间LED照明的体外检测肉毒神经毒素A活性的探测器
Steven Sun,Jesse Francis,Kim E Sapsford et al.
Steven Sun et al.
A portable and rapid detection system for the activity analysis of Botulinum Neurotoxins (BoNT) is needed for food safety and bio-security applications. To improve BoNT activity detection, a previously designed portable charge-coupled devic...
Optical and physical characterization of a local evanescent array coupled biosensor: Use of evanescent field perturbations for multianalyte sensing [0.03%]
一种局部倏逝阵列生物传感器的光学和物理性能研究及利用倏逝场扰动进行多元分析检测
Matthew D Stephens,Guangwei Yuan,Kevin L Lear et al.
Matthew D Stephens et al.
The evanescent field surrounding the core of an optical waveguide is very sensitive to refractive index changes near the core. This sensitivity can be exploited to form the basis for a quantitative sensor with high specificity and sensitivi...
Osmotic Swelling Pressure Response of Smart Hydrogels Suitable for Chronically-Implantable Glucose Sensors [0.03%]
适合慢性植入型葡萄糖传感器的智能水凝胶的渗透膨胀压力响应关系研究
G Lin,S Chang,H Hao et al.
G Lin et al.
In the last few years, a new type of glucose-sensitive hydrogel (GSH) has been developed that shrinks with increasing glucose concentration due to the formation of reversible crosslinks The first osmotic swelling pressure results measured f...
Zonghuan Lu,Jay McMahon,Hisham Mohamed et al.
Zonghuan Lu et al.
We report the investigation of a novel microfluidic mixing device to achieve submillisecond mixing. The micromixer combines two fluid streams of several microliters per second into a mixing compartment integrated with two T- type premixers ...
Chemically Polymerized Polypyrrole for On-Chip Concentration of Volatile Breath Metabolites [0.03%]
用于芯片上浓缩挥发性呼吸代谢物的化学聚吡咯
Nicholas Strand,Abhinav Bhushan,Michael Schivo et al.
Nicholas Strand et al.
A wide range of metabolites are measured in the gas phase of exhaled human breath, and some of these biomarkers are frequently observed to be up- or down-regulated in certain disease states. Portable breath analysis systems have the potenti...
Characteristics of a cobalt-based phosphate microelectrode for in situ monitoring of phosphate and its biological application [0.03%]
一种钴基磷酸盐微电极的特性及其在原位监测和生物应用中的特征研究
Woo Hyoung Lee,Youngwoo Seo,Paul L Bishop
Woo Hyoung Lee
The in situ monitoring of phosphate has been of great importance in many environmental applications, particularly those involving biological treatment processes and eutrophication monitoring. A microelectrode with small tip size (~10 mum) w...
Design, fabrication and test of a microfluidic nebulizer chip for desorption electrospray ionization mass spectrometry [0.03%]
用于解吸电喷雾离子化质谱的微流体芯片的设计、制作与测试研究
A K Sen,J Darabi,D R Knapp
A K Sen
This paper presents design, microfabrication, and test of a microfluidic nebulizer chip for desorption electrospray ionization mass spectrometry (DESI-MS) in proteomic analysis. The microfluidic chip is fabricated using cyclic olefin copoly...
C Parks Cheney,B Srijanto,D L Hedden et al.
C Parks Cheney et al.
Traditional alcohol studies measure blood alcohol concentration to elucidate the biomedical factors that contribute to alcohol abuse and alcoholism. These measurements require large and expensive equipment, are labor intensive, and are disr...
Enhanced Detection Resonance Frequency Shift of a Piezoelectric Microcantilever Sensor by a DC Bias Electric Field in Humidity Detection [0.03%]
偏置直流电场下压电微天平湿度检测的灵敏度改善研究
Qing Zhu,Wan Y Shih,Wei-Heng Shih
Qing Zhu
We have examined the relative longitudinal flexural resonance frequency shift of a PMN-PT/tin PEMS with a DC bias electric field, E, in humidity detection. We showed that the relative resonance frequency shift could be enhanced by applying ...
Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects [0.03%]
校正探针输送和组织吸收效应的蛋白酶活性定量测量方法
Christopher D Salthouse,Fred Reynolds,Jenny M Tam et al.
Christopher D Salthouse et al.
Proteases play important roles in a variety of pathologies from heart disease to cancer. Quantitative measurement of protease activity is possible using a novel spectrally matched dual fluorophore probe and a small animal lifetime imager. T...