Dual-clamped one-pot SERS-based biosensors for rapid and sensitive detection of SARS-CoV-2 using portable Raman spectrometer [0.03%]
使用便携式拉曼光谱仪检测SARS-CoV-2的双钳位一步表面增强拉曼生物传感器快速灵敏检测%SERS-Based Biosensors for Rapid and Sensitive Detection of SARS-CoV-2 Using Portable Raman Spectrometer
Kiran Kaladharan,Kuan-Hung Chen,Pin-Han Chen et al.
Kiran Kaladharan et al.
Rapid and sensitive diagnostics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is of utmost importance to control the widespread coronavirus disease 2019 (COVID-19) upsurge. This study demonstrated a novel one-pot surface-e...
PATHPOD - A loop-mediated isothermal amplification (LAMP)-based point-of-care system for rapid clinical detection of SARS-CoV-2 in hospitals in Denmark [0.03%]
PATHPOD－一种基于环介导等温扩增(LAMP)的床旁系统，用于丹麦医院中SARS-CoV-2的快速临床检测
Trieu Nguyen,Aaydha Chidambara Vinayaka,Van Ngoc Huynh et al.
Trieu Nguyen et al.
Sensitive and rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a vital goal in the ongoing COVID-19 pandemic. We present in this comprehensive work, for the first time, detailed fabrication and clinic...
CRISPR-powered Biosensing Platform for Quantitative Detection of Alpha-fetoprotein by a Personal Glucose Meter [0.03%]
基于CRISPR的生物传感平台使用个人血糖仪进行定量检测甲胎蛋白
Zhengyang Jia,Ziyue Li,Changchun Liu
Zhengyang Jia
Alpha-fetoprotein (AFP) is an important protein biomarker of liver cancer, as its serum levels are highly correlated with the progression of disease. Conventional immunoassays for AFP detection rely on enzyme-linked immunosorbent assay anal...
Enhancement of faradaic current in an electrochemical cell integrated into silicon microfluidic channels [0.03%]
集成在硅微流体通道中的电化学电池的法拉第电流增强技术
Christopher Kenji Brenden,Hrishikesh Iyer,Yan Zhang et al.
Christopher Kenji Brenden et al.
Implantable electrochemical sensors enable fast and sensitive detection of analytes in biological tissue, but are hampered by bio-foulant attack and are unable to be recalibrated in-situ. Herein, an electrochemical sensor integrated into ul...
One-step-one-pot hydrothermally derived metal-organic-framework-nanohybrids for integrated point-of-care diagnostics of SARS-CoV-2 viral antigen/pseudovirus utilizing electrochemical biosensor chip [0.03%]
一步一锅水热法制备的金属有机框架纳米杂化材料用于SARS-CoV-2病毒抗原/假病毒感染的一体化即时诊疗电化学生物芯片
Sathyadevi Palanisamy,Li-Yun Lee,Chih-Fei Kao et al.
Sathyadevi Palanisamy et al.
The COVID-19 pandemic has become a global catastrophe, affecting the health and economy of the human community. It is required to mitigate the impact of pandemics by developing rapid molecular diagnostics for SARS-CoV-2 virus detection. In ...
MASTR Pouch: Palm-size lab for point-of-care detection of Mpox using recombinase polymerase amplification and CRISPR technology [0.03%]
MASTR Pouch：使用重组酶聚合酶扩增和CRISPR技术的即诊猴痘检测设备
Jia Wei,Wanjun Wang,Qiong Yu et al.
Jia Wei et al.
Mpox (formerly referred as Monkeypox) outbreak has been declared a Public Health Emergency of International Concern. However, traditional polymerase chain reaction (PCR) diagnostic technology is not ideal for on-site applications. To conduc...
Sirowan Ruantip,Umaporn Pimpitak,Sirirat Rengpipat et al.
Sirowan Ruantip et al.
Equipment-free colorimetric-based lateral flow immunoassay (LFIA) is the most convenient and popular tool for various applications, including diagnostic tools requiring high sensitivity for the detection of pathogens. Thus, improvements and...
Longitudinal analysis of anti-SARS-CoV-2 neutralizing antibody (NAb) titers in vaccinees using a novel giant magnetoresistive (GMR) assay [0.03%]
一种新型巨磁阻(GMR)测定法对疫苗接种者中和抗体滴度的纵向分析
Elaine Ng,Christopher Choi,Shan X Wang
Elaine Ng
The COVID-19 pandemic has highlighted the need to monitor important correlates of immunity on a population-wide level. To this end, we have developed a competitive assay to assess neutralizing antibody (NAb) titer on the giant magnetoresist...
Ultra-sensitive specific detection of nucleic acids in pathogenic infections by Ta2C-MXene sensitization-based ultrafine plasmon spectroscopy combs [0.03%]
基于Ta₂C MXene 敏化超细等离子体光谱齿梳的病原感染核酸超灵敏检测
Wen Yang,Jie Yan,Runcheng Liu et al.
Wen Yang et al.
Accurate and rapid population-scale screening techniques based on SARS-CoV-2 RNA are essential in preventing and controlling the COVID-19 epidemic. However, the sensitivity and specificity of the assay signal are challenged by the problems ...
An ultrasensitive ELISA to assay femtomolar level SARS-CoV-2 antigen based on specific peptide and tyramine signal amplification [0.03%]
基于特异性肽和邻苯二酚胺信号放大的超灵敏ELISA检测飞克级SARS-CoV-2抗原
Junchong Liu,Shuang Pang,Mingyang Wang et al.
Junchong Liu et al.
The SARS-CoV-2 spreading rapidly has aroused catastrophic public healthcare issues and economy crisis worldwide. It plays predominant role to rapidly and accurately diagnose the virus for effective prevention and treatment. As an abundant t...