Assessing Aptamer-Analyte Binding Kinetics by Microfluidic Fluorescence Microscopy [0.03%]
基于微流控荧光显微镜的适配体-分析物结合动力学研究
Kechun Wen,Xin Meng,Chengxi Wang et al.
Kechun Wen et al.
Kinetic measurement plays a crucial role in understanding aptamer binding mechanisms and identifying appropriate aptamers for clinical and research applications. Current techniques, while well established, generally require large sample vol...
Engineering vascularized skin-mimetic phantom for non-invasive Raman spectroscopy [0.03%]
用于无创拉曼光谱的工程血管化皮肤仿体
Piyush Raj,Lintong Wu,Saransh Arora et al.
Piyush Raj et al.
Recent advances in Raman spectroscopy have shown great potential for non-invasive analyte sensing, but the lack of a standardized optical phantom for these measurements has hindered further progress. While many research groups have develope...
Taron M Bradshaw,Courtney R Johnson,Christopher A Broberg et al.
Taron M Bradshaw et al.
Nitric oxide (NO) release from S-nitrosothiol-modified mesoporous silica nanoparticles imbedded in the diffusion limiting layer of a glucose sensor has been demonstrated as an effective strategy for mitigating the foreign body response comm...
Suppression of Resistive Coupling in Nanogap Electrochemical Cell: Resolution of Dual Pathways for Dopamine Oxidation [0.03%]
纳米间隙电化学池中电阻耦合的抑制作用：多巴胺氧化双重路径的解析
Amir Amiri,Manu Jyothi Ravi,Siao-Han Huang et al.
Amir Amiri et al.
A nanogap cell involves two working electrodes separated by a nanometer-wide solution to enable unprecedented electrochemical measurements. The powerful nanogap measurements, however, can be seriously interfered with by resistive coupling b...
Self-powered freestanding multifunctional microneedle-based extended gate device for personalized health monitoring [0.03%]
自供能独立式多功能微针扩展示意图装置用于个性化健康监测
Rawan Omar,Miaomiao Yuan,Jing Wang et al.
Rawan Omar et al.
Online monitoring of prognostic biomarkers is critically important when diagnosing disorders and assessing individuals' health, especially for chronic and infectious diseases. Despite this, current diagnosis techniques are time-consuming, l...
Electrochemical Immunosensor for the Quantification of Galectin-3 in Saliva [0.03%]
用于测定唾液中半乳糖凝集素-3的电化学生物传感器
Trey W Pittman,Xi Zhang,Chamindie Punyadeera et al.
Trey W Pittman et al.
Heart failure (HF) is an emerging epidemic and remains a major clinical and public health problem. Advances in the healthcare management of HF may lead to lower morbidity and mortality rates but require diagnostics to guide the process. Cur...
Role of Electrode Configuration and Morphology in Printed Prothrombin Time Sensors [0.03%]
印刷型凝血酶时间传感器中电极配置和形貌的作用研究
Brittani L Huegen,James L Doherty,Brittany N Smith et al.
Brittani L Huegen et al.
Patients on long-term anticoagulation therapy require frequent testing of prothrombin time/international normalized ratio (PT/INR) to ensure therapeutic efficacy. Point-of-care (POC) PT tests for at-home monitoring eliminate the burden of v...
Nikolaos Salaris,Paul Haigh,Ioannis Papakonstantinou et al.
Nikolaos Salaris et al.
Absolute oxygen sensors based on quenching of phosphorescence have been the subject of numerous studies for the monitoring of biological environments. Here, we used simple fabrication techniques with readily available polymers to obtain hig...
An ultra low-cost smartphone device for in-situ monitoring of acute organophosphorus poisoning for agricultural workers [0.03%]
一种低成本智能手机设备 帮助农业工作者现场监测急性磷中毒
Yu-Chung Chang,Xiaoxiao Ge,Li-Ju Wang et al.
Yu-Chung Chang et al.
In this work, we present an ultra-low-cost smartphone device for in situ quantification of OP poisoning severity. The performance of the lens-less smartphone spectrum apparatus (LeSSA) is evaluated using standard human Interleukin-6 (IL-6) ...
Label-free detection of synthetic, full genomic length HIV-1 RNA at the few-copy level [0.03%]
在极少拷贝水平上无标记检测全长合成HIV-1 RNA
Olivia O Dickens,Inayat Bajwa,Kelly Garcia-Ramos et al.
Olivia O Dickens et al.
Oligonucleotide-functionalized graphene biosensors show immense promise for use as label-free point of care devices for detection of nucleic acid biomarkers at clinically relevant levels. Graphene-based nucleic acid sensors can be fabricate...