Electrochemiluminescence aptasensor for Siglec-5 detection based on MoS2@Au nanocomposites emitter and exonuclease III-powered DNA walker [0.03%]
基于MoS2@Au纳米复合发光材料和DNA行走在外切酶III作用下指数放大信号的Siglec-5检测电化学生物传感器
Zhenqiang Fan,Bo Yao,Yuedi Ding et al.
Zhenqiang Fan et al.
Lectins are highly specific binding proteins for glycoproteins which widely exist in living organisms, playing a vital role in exploring the biological evolution process, such as cellular proliferation, differentiation, carcinogenesis and a...
Ramachandram Badugu,Henryk Szmacinski,E Albert Reece et al.
Ramachandram Badugu et al.
The ability to measure all the electrolyte concentrations in tears would be valuable in ophthalmology for research and diagnosis of dry eye disease (DED) and other ocular pathologies. However, tear samples are difficult to collect and analy...
Recent progress, challenges, and opportunities for wearable biochemical sensors for sweat analysis [0.03%]
可穿戴生化传感器在汗液分析中的最新进展、挑战与机遇
Roozbeh Ghaffari,John A Rogers,Tyler R Ray
Roozbeh Ghaffari
Sweat is a promising, yet relatively unexplored biofluid containing biochemical information that offers broad insights into the underlying dynamic metabolic activity of the human body. The rich composition of electrolytes, metabolites, horm...
Utilization of chromogenic enzyme substrates for signal amplification in multiplexed detection of biomolecules using surface mass spectrometry [0.03%]
基于表面质谱的生物大分子多重检测中酶底物信号增强方法学研究
Hee-Kyung Na,Hyun Kyong Shon,Hye Young Son et al.
Hee-Kyung Na et al.
MicroRNAs (miRNAs) are important post-transcriptional gene regulators and can serve as potential biomarkers for many diseases. Most of the current miRNA detection techniques require purification from biological samples, amplification, label...
Point-of-care test system for detection of immunoglobulin-G and -M against nucleocapsid protein and spike glycoprotein of SARS-CoV-2 [0.03%]
用于检测SARS-CoV-2核衣壳蛋白和刺突糖蛋白免疫球蛋白G和免疫球蛋白M的点-of-care检测系统
Tao Peng,Zhiwei Sui,Zhenghui Huang et al.
Tao Peng et al.
The coronavirus disease 2019 (COVID-19) epidemic continues to ravage the world. In epidemic control, dealing with a large number of samples is a huge challenge. In this study, a point-of-care test (POCT) system was successfully developed an...
Paper biosensors for detecting elevated IL-6 levels in blood and respiratory samples from COVID-19 patients [0.03%]
用于检测COVID-19患者血液和呼吸道样本中IL-6水平升高的纸基生物传感器
Cristina Adrover-Jaume,Alejandra Alba-Patiño,Antonio Clemente et al.
Cristina Adrover-Jaume et al.
Decentralizing COVID-19 care reduces contagions and affords a better use of hospital resources. We introduce biosensors aimed at detecting severe cases of COVID-19 in decentralized healthcare settings. They consist of a paper immunosensor i...
Cobalt metal-organic framework modified carbon cloth/paper hybrid electrochemical button-sensor for nonenzymatic glucose diagnostics [0.03%]
用于非酶葡萄糖诊断的钴金属有机骨架修饰碳布/纸混合电化学按钮传感器
Xiaofeng Wei,Jialei Guo,Huiting Lian et al.
Xiaofeng Wei et al.
In the growing pandemic, family healthcare is widely concerned with the increase of medical self-diagnosis away from the hospital. A cobalt metal-organic framework modified carbon cloth/paper (Co-MOF/CC/Paper) hybrid button-sensor was devel...
Kaleidoscopic fluorescent arrays for machine-learning-based point-of-care chemical sensing [0.03%]
用于机器学习的基于POC化学传感的荧光阵列
Hyungi Kim,Sang-Kee Choi,Jungmo Ahn et al.
Hyungi Kim et al.
Multiplexed analysis allows simultaneous measurements of multiple targets, improving the detection sensitivity and accuracy. However, highly multiplexed analysis has been challenging for point-of-care (POC) sensing, which requires a simple,...
Development of a SERS-based lateral flow immunoassay for rapid and ultra-sensitive detection of anti-SARS-CoV-2 IgM/IgG in clinical samples [0.03%]
开发一种基于SERS的侧向流动免疫测定法，以快速和超灵敏地检测临床样本中的抗SARS-CoV-2 IgM / IgG
Haifeng Liu,Erhei Dai,Rui Xiao et al.
Haifeng Liu et al.
The accurate and rapid screening of serum antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the key to control the spread of 2019 coronavirus disease (COVID-19). In this study, we reported a surface-enhanced...
MIPs for commercial application in low-cost sensors and assays - An overview of the current status quo [0.03%]
低コストセンサーとアッセイの商業アプリケーションにおけるMIPの現状について概観する
Joseph W Lowdon,Hanne Diliën,Pankaj Singla et al.
Joseph W Lowdon et al.
Molecularly imprinted polymers (MIPs) have emerged over the past few decades as interesting synthetic alternatives due to their long-term chemical and physical stability and low-cost synthesis procedure. They have been integrated into many ...