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The mechanism of curcumin protecting against IL-1β-induced oxidative stress and inflammation in chondrocytes via the Bmp2/Smad5/Runx2 pathway [0.03%] 姜黄素通过Bmp2/Smad5/Runx2通路保护IL-1β诱导的软骨细胞氧化应激和炎症的机制研究
Jinlei Li,Weitong Liu,Tao Wang et al. Jinlei Li et al.
A core role of chondrocyte survival/death has been suggested in the pathogenesis of osteoarthritis. We explored the underlying molecular mechanism of curcumin protecting against interleukin-1β (IL-1β)-induced chondrocyte injury via the bo...
The effect of exosomes from canine bone mesenchymal stem cells on IL-1β-mediated inflammatory responses in chondrocytes [0.03%] 犬骨髓间充质干细胞外泌体对白介素-1β诱导的软骨细胞炎症反应的影响
Nan Jiang,Shuna Yang,Yunfei Sun et al. Nan Jiang et al.
Osteoarthritis is a degenerative disease of cartilage, and exosome derived from mesenchymal stem cells (MSCs) are considered promising for treating inflammatory musculoskeletal disorders, although their mechanisms are not fully understood. ...
Melatonin enhances therapeutic outcomes of adipose tissue-derived mesenchymal stem cell therapy in rat osteoarthritis by reducing TNF-α and IL-1β-induced injuries [0.03%] 褪黑素通过减少TNF-α和IL-1β诱导的损伤增强脂肪组织来源的间充质干细胞治疗骨关节炎的效果
Hao Jiang,Jiafang Chen,Zhangya Lin et al. Hao Jiang et al.
Although adipose tissue-derived mesenchymal stem cell (ADSC) transplantation has been effectively used to treat osteoarthritis (OA), the low cell survival rate induced by the inflammatory and oxidative stress, severely affects the therapeut...
Bioinformatics analysis of synovial fluid-derived mesenchymal stem cells in the temporomandibular joint stimulated with IL-1β [0.03%] 细胞因子IL-1β激活颞下颌关节滑膜间充质干细胞的生物信息学分析
Yiting Lou,Ran Tao,Xiaoyan Weng et al. Yiting Lou et al.
The stimulation of interleukin-1β (IL-1β) is the risk factor for temporomandibular joint osteoarthritis (TMJOA). We aim to investigate IL-1β stimulation-related gene and signal pathways in synovial fluid-derived mesenchymal stem cells (S...