Genetics of human growth [0.03%]
人类生长的遗传学
Tsutomu Ogata
Tsutomu Ogata
Genes involved in human growth consist of major growth genes and minor growth genes. Major growth genes have fundamental effects on human growth, and their mutations cause growth failure (or overgrowth) which are recognizable as single gene...
A novel v2 vasopressin receptor mutation with x-linked nephrogenic diabetes insipidus [0.03%]
一种新的V2血管加压素受体突变与X连锁遗传型尿崩症相关的研究
Takayuki Okamoto,Norio Kobayashi,Hiroyuki Naito et al.
Takayuki Okamoto et al.
Three-Year Follow-up Study on Serum Leptin Levels in GH Deficient Children with GH Replacement Therapy [0.03%]
生长激素缺乏症患儿替代治疗三年的血清瘦素水平随访研究
Megumi Kishi,Yukashi Ohki,Hiromi Orimo
Megumi Kishi
Interactions between GH and leptin have been extensively studied. However, results of long-term GH therapy on serum leptin levels in GH-deficient children were not consistent. Moreover, no such reports were available in Japanese children wi...
Nutrient-enriched Diet in the Early Neonatal Period Influences the 3 year-old Height in Very Low Birth Weight Infants [0.03%]
早产儿出生后早期摄入营养素对其三岁前身高影响的研究
Kitaro Kosaka,Satoshi Hada,Kensuke Matsuo et al.
Kitaro Kosaka et al.
Nutrient-enriched milk has been advocated to enhance premature infants'growth and early nutritional intervention is effective for growth failure in very low birth weight infants (VLBWI). We studied the 3-yr-old physical growth of VLBWI who ...
A spectrum of clinical presentations in seven Japanese patients with vitamin d deficiency [0.03%]
日本7例维生素D缺乏患者的临床表现谱
Takuo Kubota,Tomoo Kotani,Yoko Miyoshi et al.
Takuo Kubota et al.
Recently, the reemergence of vitamin D deficiency in developed countries has been pointed out. Vitamin D deficiency is diagnosed based on the serum 25-hydroxyvitamin D (25OHD) level. However, its normal range is still controversial, making ...
No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment [0.03%]
非生长激素缺乏矮小儿童的生长激素治疗对其成人身高无改善作用
Toshiaki Tanaka,Kenji Fujieda,Susumu Yokoya et al.
Toshiaki Tanaka et al.
It is still in doubt whether the standard-dose growth hormone (GH) used in Japan (0.5 IU/kg/week, 0.167 mg/kg/week) for growth hormone deficiency is effective for achieving significant adult height improvement in non-growth hormone deficien...
Iosif Kelesidis,Christos S Mantzoros
Iosif Kelesidis
Leptin is an adipocyte-secreted hormone which plays a key role in energy homeostasis. Recent "proof of concept" studies involving leptin administration to humans support its critical role in regulating energy homeostasis, neuroendocrine and...
Survey of current medical treatments for childhood-onset type 2 diabetes mellitus in Japan [0.03%]
日本儿童2型糖尿病的治疗现状调查
Shigetaka Sugihara,Nozomu Sasaki,Hitoshi Kohno et al.
Shigetaka Sugihara et al.
The prevalence of childhood-onset type 2 diabetes mellitus has increased dramatically over the past two or three decades in Japan, but epidemiological and clinical data remain limited. This survey was conducted to elucidate the current use ...
A case with hyperthyroidism who had been treated with thyroid hormone because of congenital hypothyroidism [0.03%]
先天性甲状腺功能减退症用甲状腺激素治疗后并发甲亢一例报告
Kiyoko Otsubo,Michiyo Mizota,Kazuko Hizukuri et al.
Kiyoko Otsubo et al.
We encountered a case with hyperthyroidism at the age of 14 who had been diagnosed with congenital hypothyroidism (CH) and had received thyroid hormone replacement therapy. At the age of 16 d, the patient was referred to our hospital becaus...
Retrospective analysis of infants designated as positive on mass-screening for congenital hypothyroidism at kagoshima university [0.03%]
九州大学群体新生儿先天性甲状腺功能减低筛查阳性婴儿的回顾分析
Izumi Tamada,Michiyo Mizota,Kazuko Hizukuri et al.
Izumi Tamada et al.
Mass-screening for congenital hypothyroidism has identified cases of mild hypothyroidism, transient hypothyroidism, and transient hyperthyrotropinemia as well as typical hypothyroidism. In this paper, we examine the clinical data of the cas...