Clinical features of neonatal Graves' disease revealed by twelve cases that require- antithyroid therapy [0.03%]
12例需抗甲状腺治疗的新生儿Graves病临床特征分析
Eriko Adachi,Ryosei Iemura,Yumi Tanaka et al.
Eriko Adachi et al.
Neonatal Graves' disease (GD) is rare and serious condition with a complicated clinical course, its details of the clinical features have not been clarified. This study aimed to clarify the clinical course of neonatal GD cases requiring ant...
Hydrocortisone dosage at 3 years of age is positively correlated with body mass index at 10 years in individuals with 21-hydroxylase deficiency [0.03%]
3岁年龄的氢化可的松剂量与21-羟化酶缺乏个体10岁时的身体质量指数呈正相关
Yuki Miyahara,Ayaha Hata,Tamaki Wada et al.
Yuki Miyahara et al.
Obesity is a major complication in individuals with 21-hydroxylase deficiency (21-OHD) and excessive hydrocortisone (HC) dosing is a likely contributing factor. However, the association between the HC dosage and body mass index (BMI) during...
Burosumab treatment for FGF23-related hypophosphatemia in a two-year-old girl with McCune-Albright syndrome [0.03%]
布索马布治疗McCune-Albright综合征两岁女童纤维囊性骨发育不良相关低磷血症
Tomoki Saito,Kana Hiromoto,Naoya Morisada et al.
Tomoki Saito et al.
McCune-Albright syndrome (MAS) is a rare mosaic disorder caused by a gain-of-function pathogenic GNAS variant that triggers endocrine and skeletal manifestations, including fibrous dysplasia (FD) and FGF23-related hypophosphatemia. Conventi...
Necrotizing enterocolitis following a single very low dose of octreotide in a patient with congenital hyperinsulinism: a case successfully managed with 18F-DOPA PET/CT-guided surgery [0.03%]
单次极低剂量奥曲肽诱发的先天性高胰岛素血症患儿坏死性小肠结肠炎一例及18F-DOPA PET/CT影像引导手术成功治疗报告
Takeshi Uehara,Haruki Mizutani,Naomi Hatabu et al.
Takeshi Uehara et al.
Octreotide is considered a second-line treatment for congenital hyperinsulinism unresponsive to diazoxide. Necrotizing enterocolitis (NEC) is a serious adverse effect of octreotide, typically occurring in a dose-dependent manner. Here, we r...
A pediatric case of central diabetes insipidus and hypopituitarism after COVID-19 suspected with lymphocytic hypophysitis with positive anti-rabphilin-3A antibodies [0.03%]
怀疑淋巴细胞性垂体炎的COVID-19后中枢性尿崩症和垂体功能减退儿科病例伴抗rabphilin-3A阳性抗体
Taro Fukuta,Tatsuya Fukasawa,Haruki Mizutani et al.
Taro Fukuta et al.
Lymphocytic hypophysitis (LYH) is a rare autoimmune disorder characterized by lymphocytic infiltration of the pituitary gland, leading to central diabetes insipidus (CDI) and hypopituitarism. Although distinguishing LYH from other diseases ...
Sayaka Kawashima,Chisumi Sogi,Dai Suzuki et al.
Sayaka Kawashima et al.
Thyroid storm is a life-threatening disorder caused by thyrotoxicosis. Diagnostic criteria in adults emphasize central nervous system (CNS) symptoms, including seizures, as CNS symptoms are associated with irreversible damage. However, chil...
Clinical practice guidelines for the management of differences of sex development in Japan [0.03%]
日本性别发育差异管理临床实践指南
Tomohiro Ishii,Kenichi Kashimada,Masanobu Kawai et al.
Tomohiro Ishii et al.
Differences of sex development (DSD) are congenital conditions in which chromosomal, gonadal, and anatomical sex characteristics are discordant with typical male or female development. These clinical practice guidelines provide evidence-bas...
Severe headache as the initial manifestation of painless thyroiditis: a pediatric case report [0.03%]
无痛性甲状腺炎初始表现为严重头痛的儿科病例报告
Risa Nagase,Yuki Kawashima,Mari Asakura et al.
Risa Nagase et al.
Painless thyroiditis is a potential cause of thyrotoxicosis, typically presenting with weakness, fatigue, irritability, palpitations, and tremors; however, headache is an uncommon manifestation. Herein, we report two pediatric cases of pain...
The serum oxytocin correlated with serum leptin and body mass index in Japanese adolescents [0.03%]
日本青少年血清催产素与血清瘦素和体质指数相关性研究
Junji Takaya,Yuko Tanabe,Naohiro Nomura et al.
Junji Takaya et al.
Oxytocin (OXT), a hypothalamic neuropeptide traditionally associated with reproduction and social bonding, has recently garnered attention for its role in regulating appetite and energy metabolism. To evaluate serum OXT levels and their ass...
Effects of a diabetes-themed cartoon-based education on disease knowledge and physical activity among Japanese children: a preliminary randomized controlled trial [0.03%]
针对日本儿童的糖尿病主题漫画教育对疾病知识和身体活动的影响：一项初步随机对照试验
Yasuhiro Suzuki,Daichi Sugawara,Mika Oki et al.
Yasuhiro Suzuki et al.
We examined whether cartoon-based diabetes education could enhance diabetes knowledge and physical activity among children. During the first visit, participants completed a diabetes knowledge test; accelerometers, which were worn, were dist...