The circadian variation of cortisol secretion in patients with anorexia nervosa in childhood and adolescence after recovery of body weight by treatment using gas chromatography/mass spectrometry in selected ion monitoring [0.03%]
儿童及青少年期厌食症康复后用气相色谱/质谱法中的选择离子监测测定成年后的皮质醇分泌的昼夜变化
Keiko Homma,Akihiro Sato,Hisako Watanabe et al.
Keiko Homma et al.
Anorexia nervosa (AN) is a chronic psychiatric disorder which is characterized by patient-induced weight loss. Complications in many organ systems can be seen in AN such as cardiovascular, gastrointestinal, and endocrine system including hy...
A case of primary hyperparathyroidism in childhood found by a chance hematuria [0.03%]
一次偶然发现血尿的原发性儿童甲状旁腺功能亢进症病例报告
Yasuhisa Ohata,Takehisa Yamamoto,Yukihiro Kitai et al.
Yasuhisa Ohata et al.
A 10-yr-old boy visited Minoh City Hospital complaining of gross hematuria. Laboratory investigations revealed hypercalcemia, hypophosphatemia, and elevated serum levels of parathyroid hormone. A stone was found in the right ureter with dri...
Prevalence of obesity, hyperlipemia and insulin resistance in children with suprasellar brain tumors [0.03%]
儿童鞍上脑肿瘤患者的肥胖、高脂血症和胰岛素抵抗的流行病学研究
Masanori Adachi,Takayoshi Tsuchiya,Koji Muroya et al.
Masanori Adachi et al.
Weight gain is a common sequela of suprasellar tumors, referred to as hypothalamic obesity. We undertook an evaluation of obesity and metabolic aberrations among patients treated at our institute. During the 12 mo from Apr. 2005, 23 patient...
Discrepancies between Physician and Parent Perceptions of Psychosocial Problems of GHD Children Undergoing GH Therapy in Japan [0.03%]
日本生长激素缺乏症儿童接受生长激素治疗期间医患双方对心理社会问题认知的差异
Osamu Arisaka,Ekaterina Koledova,Sanae Kanazawa et al.
Osamu Arisaka et al.
This study examined discrepancies between the perceptions of physicians treating short children with GH deficiency (GHD) using GH replacement therapy (GHRT) and the perceptions of the parents of these children and identified the major cause...
Mutational Analysis of Androgen Receptor (AR) Gene in 46,XY Patients with Ambiguous Genitalia and Normal Testosterone Secretion: Endocrinological Characteristics of Three Patients with AR Gene Mutations [0.03%]
雄激素受体（AR）基因突变与先天性两性畸形及睾酮分泌正常患者的内分泌特点分析三例雄激素抵抗综合征患者报道
Junko Miyamoto,Hiroshi Asanuma,Hideo Nakai et al.
Junko Miyamoto et al.
The prevalence of abnormalities in androgen receptor gene (AR) among patients with ambiguous genitalia is unknown. Moreover, endocrinological data from prepubertal patients with AR mutation are very limited. Thus, the aim of this study was ...
Akiko Maesaka,Asako Higuchi,Shinobu Kotoh et al.
Akiko Maesaka et al.
Denys-Drash syndrome (DDS) and Frasier syndrome (FS) are caused by mutations of the WT1 gene. These disorders are characterized by renal disease, abnormality of male sex differentiation, and Wilms' tumor and gonadoblastoma. There have been ...
Toshihiro Tajima,Yuichi Tabata,Kayoko Tao et al.
Toshihiro Tajima et al.
Gitelman syndrome (GS) is a renal tubular disorder characterized by hypokalemia, hypomagnesemia, metabolic alkalosis and hypocalciuria due to defective tubular reabsorption of magnesium and potassium. This disease is caused by mutations of ...
Molecular bases of diseases characterized by hypophosphatemia and phosphaturia: new understanding [0.03%]
低磷血症和高磷尿症疾病的分子发病机制：新的认识
Keiichi Ozono,Toshimi Michigami,Noriyuki Namba et al.
Keiichi Ozono et al.
Serum phosphate levels are regulated in both calcium-dependent and -independent fashions. Active vitamin D increases while PTH decreases serum phosphate levels in association with the elevation of serum calcium. On the other hand, a calcium...
Lead and growth [0.03%]
领导力与成长发展
Masayuki Kaji,Yoshikazu Nishi
Masayuki Kaji
Lead is highly toxic to the human body and children are much more vulnerable to lead toxicity than adults. Many studies have revealed that relatively low levels of blood lead can adversely affect human health, especially childhood growth an...
Clinical Evaluation of the Needle-free Injection System VISION(®) for Growth Hormone Therapy in Children [0.03%]
儿童生长激素治疗用无针注射系统VISION的临床评估研究
Yutaka Igarashi
Yutaka Igarashi
The aim of this study was to compare the therapeutic effects of rhGH administered either by subcutaneous needle-injection (pens) or subcutaneous needle-free jet-injection (VISION(®)). Furthermore, a survey was carried out after using VISIO...