Sayaka Kawashima,Chisumi Sogi,Dai Suzuki et al.
Sayaka Kawashima et al.
Thyroid storm is a life-threatening disorder caused by thyrotoxicosis. Diagnostic criteria in adults emphasize central nervous system (CNS) symptoms, including seizures, as CNS symptoms are associated with irreversible damage. However, chil...
Clinical practice guidelines for the management of differences of sex development in Japan [0.03%]
日本性别发育差异管理临床实践指南
Tomohiro Ishii,Kenichi Kashimada,Masanobu Kawai et al.
Tomohiro Ishii et al.
Differences of sex development (DSD) are congenital conditions in which chromosomal, gonadal, and anatomical sex characteristics are discordant with typical male or female development. These clinical practice guidelines provide evidence-bas...
Severe headache as the initial manifestation of painless thyroiditis: a pediatric case report [0.03%]
无痛性甲状腺炎初始表现为严重头痛的儿科病例报告
Risa Nagase,Yuki Kawashima,Mari Asakura et al.
Risa Nagase et al.
Painless thyroiditis is a potential cause of thyrotoxicosis, typically presenting with weakness, fatigue, irritability, palpitations, and tremors; however, headache is an uncommon manifestation. Herein, we report two pediatric cases of pain...
The serum oxytocin correlated with serum leptin and body mass index in Japanese adolescents [0.03%]
日本青少年血清催产素与血清瘦素和体质指数相关性研究
Junji Takaya,Yuko Tanabe,Naohiro Nomura et al.
Junji Takaya et al.
Oxytocin (OXT), a hypothalamic neuropeptide traditionally associated with reproduction and social bonding, has recently garnered attention for its role in regulating appetite and energy metabolism. To evaluate serum OXT levels and their ass...
Effects of a diabetes-themed cartoon-based education on disease knowledge and physical activity among Japanese children: a preliminary randomized controlled trial [0.03%]
针对日本儿童的糖尿病主题漫画教育对疾病知识和身体活动的影响：一项初步随机对照试验
Yasuhiro Suzuki,Daichi Sugawara,Mika Oki et al.
Yasuhiro Suzuki et al.
We examined whether cartoon-based diabetes education could enhance diabetes knowledge and physical activity among children. During the first visit, participants completed a diabetes knowledge test; accelerometers, which were worn, were dist...
Improvement in post-hemispherotomy cerebral salt-wasting syndrome following intubation: A case report [0.03%]
气管插管后半球切除术后脑性盐耗综合征的改善：病例报告
Reiko Saito,Marie Mitani-Konno,Osamu Saito et al.
Reiko Saito et al.
Cerebral salt-wasting syndrome (CSWS) is characterized by renal sodium loss following intracranial disorders, leading to hyponatremia, reduced extracellular volume, and dehydration. The mechanisms underlying CSWS remain unclear. To date, no...
A 14-yr-old boy with a pathogenic MEN1 variant was diagnosed with asymptomatic insulinoma during routine follow-up [0.03%]
一名携带MEN1致病突变的14岁男孩在常规随访中被诊断出患有无症状胰岛素瘤
Risa Yokoyama,Takumi Shibazaki,Chizuko Nakamura et al.
Risa Yokoyama et al.
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder attributed to mutations in the MEN1 gene and is characterized by multiple endocrine tumors, including insulinoma. Asymptomatic hyperinsulinemic hypoglycemia and pa...
Utility of the FT3-to-FT4 ratio as a screening marker for pediatric Graves' disease [0.03%]
FT3与FT4比值在儿童Graves病筛查中的应用价值研究
Kazuhiro Shimura,Kentaro Sawano,Keisuke Nagasaki et al.
Kazuhiro Shimura et al.
Graves' disease (GD) is the most common cause of pediatric thyrotoxicosis; however, differentiating it from other conditions is challenging. A high free triiodothyronine-to-free thyroxine ratio (FT3/FT4) ratio has been established as an ind...
Yosuke Komatsu,Nobuyuki Kikuchi
Yosuke Komatsu
Van Wyk-Grumbach syndrome (VWGS) is a rare manifestation of acquired hypothyroidism that was first described in 1960. It is characterized by precocious puberty, delayed bone age, and, in some cases, galactorrhea. We report the case of a 9-y...
A Japanese infant with fulminant type 1 diabetes with disease-sensitive CSAD polymorphism and HLA haplotype [0.03%]
一个患有进行性1型糖尿病的日籍婴儿的疾病敏感CSAD多态性和HLA单倍体基因型分析结果报告
Junko Kanno,Hirohito Shima,Miki Kamimura et al.
Junko Kanno et al.
Fulminant type 1 diabetes mellitus (FT1DM) is a subtype of type 1 diabetes (T1DM) with an acute onset. There are limited reports on FT1DM in pediatric patients. Here, we report the case of a Japanese female infant with FT1DM, representing t...