Infant growth and breastfeeding patterns: The Japan Environment and Children's Study [0.03%]
日本环境与儿童研究中的婴儿生长和母乳喂养模式
Mie Mochizuki,Hiroshi Yokomichi,Emi Sawanobori et al.
Mie Mochizuki et al.
Breastfeeding is recommended as the ideal nutrient source for infants, with the benefit of reducing future metabolic risk. Rapid catch-up growth in infancy has been associated with increased later adiposity and cardiometabolic risk. Few stu...
Efficacy and safety of GH treatment in Japanese pediatric patients with SHOX deficiency: an open-label extension study [0.03%]
生长激素治疗SHOX缺乏日本儿科患者的有效性和安全性：开放标签延长研究
Tsutomu Ogata,Sumito Dateki,Maki Fukami et al.
Tsutomu Ogata et al.
We have previously published efficacy and safety data up to 24 mo of GH treatment (0.35 mg/kg/wk) for SHOX-related short stature in 19 Japanese pediatric patients before pubertal entry (jRCT2080223889). Here, we report similar efficacy and ...
Severe infantile obesity with a maternal GNAS deletion and multi-locus imprinting disturbance including hypomethylation of the KCNQ1OT1:TSS-DMR [0.03%]
伴有母系GNAS缺失和多基因印记异常的严重婴幼儿肥胖及KCNQ1OT1:TSS-DMR低甲基化现象
Tatsuki Urakawa,Masaharu Shimada,Shinichiro Sano et al.
Tatsuki Urakawa et al.
Genetic defects in GNAS on the maternal allele cause pseudohypoparathyroidism type 1A (PHP1A) with PTH resistance. Beckwith-Wiedemann syndrome (BWS) is an overgrowth syndrome caused by aberrant methylation in the KCNQ1OT1:transcription star...
A survey on treatment satisfaction with leuprorelin acetate in girls with central precocious puberty [0.03%]
醋酸亮丙瑞林治疗中枢性早熟女童疗效的调查研究
Eri Koga,Kohei Iwata,Yoh Watanabe et al.
Eri Koga et al.
Central precocious puberty (CPP) is often treated with gonadotropin-releasing hormone (GnRH) analogs to manage compromised adult height and psychological distress. In Japan, only monthly formulations are available, and the perceived burden ...
Clinical utility of TRAb reduction in predicting remission in pediatric Graves' disease [0.03%]
TRAb减少在预测儿童Graves病缓解中的临床价值
Shintaro Terashita,Mariko Nagamori,Yasuhiro Naiki et al.
Shintaro Terashita et al.
Hyperthyroidism in childhood impairs quality of life, with Graves' disease (GD) being the predominant cause. Although most cases can be managed with antithyroid drugs (ATD), recurrence remains challenging due to its frequency and unpredicta...
Efficacy and safety of reduced-dose insulin infusion in pediatric diabetic ketoacidosis: a randomized clinical trial [0.03%]
小剂量胰岛素静脉输注治疗儿童糖尿病酮症酸中毒的有效性和安全性：一项随机临床试验
Hoda Atwa,Marwa Ali,Ahmed Ibrahim
Hoda Atwa
Diabetic ketoacidosis (DKA) management in children traditionally employs insulin infusion rates of 0.1 units/kg/h, though emerging evidence suggests lower doses may achieve comparable outcomes with enhanced safety profiles. This study aimed...
Two siblings with Schaaf-Yang syndrome treated with growth hormone [0.03%]
两名Schaaf-Yang综合征患儿生长激素治疗病例报告
Yukiko Hashimoto,Kazutaka Nanba,Yosuke Konishi et al.
Yukiko Hashimoto et al.
Schaaf-Yang syndrome (SYS) is a rare neurodevelopmental disorder with overlapping features with Prader-Willi syndrome (PWS). We report two Japanese siblings with SYS harboring a rare MAGEL2 variant (NM_019066.5:c.1621C>T, p.(Q541*)). Both p...
Long-lasting hypoglycemia through insulin degludec during acute kidney injury after diabetic ketoacidosis: A case report [0.03%]
糖尿病酮症酸中毒后急性肾损伤期间使用德谷胰岛素导致长时间低血糖的个案报告
Sayaka Kawashima,Tomohisa Suzuki,Hirohito Shima et al.
Sayaka Kawashima et al.
Diabetic ketoacidosis (DKA) may be complicated by acute kidney injury (AKI). While the pharmacokinetics of insulin degludec were previously suggested to be stable even in chronic kidney disease, its safety profile in acute or dynamic renal ...
Incidence and clinical characteristics of pediatric vitamin D deficiency in Hokkaido, Japan: A survey of cases diagnosed between 2015 and 2019 [0.03%]
日本北海道地区2015年至2019年儿童维生素D缺乏的发病及临床特征：一项病例调查研究
Shinsuke Fukui,Takamasa Miyoshi,Tomoka Tsubota et al.
Shinsuke Fukui et al.
Vitamin D deficiency and rickets are important pediatric health concerns, particularly in high-latitude regions. This study investigated the incidence and clinical characteristics of pediatric vitamin D deficiency in Hokkaido, Japan, betwee...
Association between perinatal growth restriction and subsequent body build in very-low-birth-weight infants [0.03%]
早产儿体重不足和低出生体重婴儿后续身体发育之间的关系
Akinori Shichijo,Keisuke Nakamura,Hiroyuki Tomino et al.
Akinori Shichijo et al.
The present study assessed the influence of perinatal growth restriction on subsequent body build until nine years old in very-low-birth-weight infants (VLBWIs). Growth restriction was defined as being born small for gestational age (SGA) o...