Retraction: Nuclear Morphometric Analysis of Leydig Cells of Male Pubertal Rats Exposed In Utero to Di(n-butyl) Phthalate [0.03%]
撤稿：内源暴露于邻苯二甲酸二正丁酯的雄性大鼠青春期 Leydig 细胞核形态计量分析
Shin Wakui,Masaya Motohashi,Takemi Satoh et al.
Shin Wakui et al.
[This retracts the article on p. 439 in vol. 26, PMID: 24526819.]. ©2023 The Japanese Society of Toxicologic Pathology.
Retraction of Publication
Journal of toxicologic pathology. 2023 Oct;36(4):212. DOI:10.1293/tox.36.R1 2023
Satoshi Furukawa,Naho Tsuji,Seigo Hayashi et al.
Satoshi Furukawa et al.
A fused triplet placenta was observed in a Wistar Hannover rat on gestation day 15. Each placenta (referred to as PL-A, PL-B, and PL-C) of this fused placenta was attached to one fetus each, but their fetal weights were lower than that of t...
Pathological analysis of lesions in the exocrine pancreas of rats induced by Zinc Maltol [0.03%]
焦谷氨酸锌诱导的大鼠外分泌胰腺病变的病理分析
Sakura Fujiwara,Takayasu Moroki,Masaya Hitomi et al.
Sakura Fujiwara et al.
The pancreas plays an important role in the homeostasis of zinc (Zn), a nutritionally essential metal. In several previous studies, Zn ions induced inflammatory changes in the exocrine pancreas; however, little is known about Zn complexes. ...
Satoshi Furukawa,Naho Tsuji,Seigo Hayashi et al.
Satoshi Furukawa et al.
We examined the morphological effects of cyclophosphamide (CPA) on placental development in pregnant rats. CPA was administered as a single dose to pregnant rats intraperitoneally at 0 mg/kg (the control group), 25 mg/kg on gestation day (G...
Pretreatment with tadalafil attenuates cardiotoxicity induced by combretastatin A4 disodium phosphate in rats [0.03%]
他达拉菲预处理减轻朴金果素A4钠磷盐致大鼠心毒性
Yoshiyasu Nagashima,Ryota Tochinai,Shin-Ichi Sekizawa et al.
Yoshiyasu Nagashima et al.
Combretastatin A4 disodium phosphate (CA4DP) is a prodrug of combretastatin A4 (CA4), a microtubule-disassembling agent that exhibits antitumor effects by inhibiting tumor cell proliferation and inducing morphological changes and apoptosis ...
Analyses of damage-associated molecular patterns, particularly biglycan, in cisplatin-induced rat progressive renal fibrosis [0.03%]
顺铂诱导的大鼠进行性肾纤维化损伤相关分子模式(特别是大角蛋白)的研究分析
Minto Nakagawa,Takeshi Izawa,Mitsuru Kuwamura et al.
Minto Nakagawa et al.
Damage-associated molecular patterns (DAMPs) and their receptors (TLR-2 and -4) may play important roles in renal fibrosis, of which the pathogenesis is complicated. We used rat renal lesions induced by a single intraperitoneal injection of...
Twelve-month in utero safety assessment of gardenia blue, a natural food colorant [0.03%]
宫内安全性的12个月评估的一种天然色素——蓝 Gardenia Blue
Robert R Maronpot,Michael Streicker,Debabrata Mahapatra et al.
Robert R Maronpot et al.
Toxicity assessment of the food colorant Gardenia jasminoides Ellis at dietary exposures of 0.0%, 0.1%, 0.5%, 1.5%, 3.0% and 5.0% included measures of T-cell- dependent antibody response, neurotoxicity, and clinical and anatomic pathology i...
A carcinogenicity study of diphenylarsinic acid in C57BL/6J mice in drinking water for 78 weeks [0.03%]
饮水染毒二苯基砷酸致C57BL/6J小鼠致癌性研究
Takashi Yamaguchi,Min Gi,Masaki Fujioka et al.
Takashi Yamaguchi et al.
Diphenylarsinic acid (DPAA), a neurotoxic organic arsenical, is present in groundwater and soil in some regions of Japan owing to illegal dumping. The present study evaluated the potential carcinogenicity of DPAA, including investigating wh...
Morphological characteristics and notes of the skin in preclinical toxicity assessment [0.03%]
毒理学预试验中皮肤组织形态特点及注意事项
Takayasu Moroki
Takayasu Moroki
In this review, the histological structures of the skin are summarized for fundamental knowledge for toxicological assessment. The skin is composed of epidermis, dermis, subcutaneous tissue, and associated adnexa. In the epidermis, keratino...
Contribution of toxicological pathology to occupational health: lung carcinogenicity of fibrous and particulate substances in rats [0.03%]
毒理病理学对职业健康贡献的评价：关于大鼠肺纤维化和颗粒物质致癌性的研究
Shoji Fukushima,Tatsuya Kasai,Hideki Senoh et al.
Shoji Fukushima et al.
In this review, we focus on the rat pulmonary carcinogenicity of two solid substances, fibrous multi-walled carbon nanotube (MWCNT) and particulate indium tin oxide (ITO). Inhalation exposure to MWNT-7, a type of MWCNTs, and ITO induced lun...