Takuma Yamamoto,Yuko Emoto,Takehiko Murase et al.
Takuma Yamamoto et al.
Japan has various death investigation systems; however, external examinations, postmortem computed tomography, macroscopic examinations, and microscopic examinations are performed regardless of the system used. These examinations can reveal...
Spontaneous mandibular follicular ameloblastoma in a female Sprague-Dawley rat [0.03%]
雌性斯普拉格-道利(Sprague-Dawley)大鼠下颌自发成釉细胞瘤病变
Juan Li,Guojian Jiang,Jie Zhang et al.
Juan Li et al.
Ameloblastoma is a locally aggressive tumor derived from the odontogenic epithelium of the developing tooth germ. It is rarely reported in experimental Sprague-Dawley (SD) rats. In this 90-day percutaneous repeated-dose toxicity study, mand...
Pathogenesis of chemically induced nasal cavity tumors in rodents: contribution to adverse outcome pathway [0.03%]
化学诱导啮齿动物鼻腔肿瘤的发病机理：对不利结局通道的贡献
Akiyoshi Nishikawa,Kasuke Nagano,Hajime Kojima et al.
Akiyoshi Nishikawa et al.
The pathogenesis of nasal cavity tumors induced in rodents has been critically reviewed. Chemical substances that induce nasal cavity tumors in rats, mice, and hamsters were searched in the National Toxicology Program (NTP), International A...
Identifying the dataset to define the optimal timing of histopathological examination for central nervous system toxicity in MPTP-induced Parkinson's disease monkey model [0.03%]
识别数据集以定义MPTP诱导的帕金森病猴模型中枢神经系统毒性的最佳病理检查时间点
Hironobu Yasuno,Yasushi Masuda,Harushige Ozaki et al.
Hironobu Yasuno et al.
Determining the optimal timing for histopathological examination following exposure to a test article is crucial for assessing neurotoxicity. However, no study has focused on identifying an ideal dataset to define the optimal timing for his...
Smooth muscle hamartoma of the lungs in a Wistar Hannover rat [0.03%]
郑宫氏平滑肌错构瘤的肺部病变一窝汉诺威Wistar大鼠发生案
Shinya Miyazaki,Chinatsu Fujiwara,Yoshitaka Katoh et al.
Shinya Miyazaki et al.
Hamartomas are tumor-like masses comprising disorganized normal tissue elements. To date, spontaneous hamartomas have been reported in several organs and tissues in rodents but not in the lungs. Here, we report the first case of a hamartoma...
Retraction: Nuclear Morphometric Analysis of Leydig Cells of Male Pubertal Rats Exposed In Utero to Di(n-butyl) Phthalate [0.03%]
撤稿：内源暴露于邻苯二甲酸二正丁酯的雄性大鼠青春期 Leydig 细胞核形态计量分析
Shin Wakui,Masaya Motohashi,Takemi Satoh et al.
Shin Wakui et al.
[This retracts the article on p. 439 in vol. 26, PMID: 24526819.]. ©2023 The Japanese Society of Toxicologic Pathology.
Retraction of Publication
Journal of toxicologic pathology. 2023 Oct;36(4):212. DOI:10.1293/tox.36.R1 2023
Satoshi Furukawa,Naho Tsuji,Seigo Hayashi et al.
Satoshi Furukawa et al.
A fused triplet placenta was observed in a Wistar Hannover rat on gestation day 15. Each placenta (referred to as PL-A, PL-B, and PL-C) of this fused placenta was attached to one fetus each, but their fetal weights were lower than that of t...
Pathological analysis of lesions in the exocrine pancreas of rats induced by Zinc Maltol [0.03%]
焦谷氨酸锌诱导的大鼠外分泌胰腺病变的病理分析
Sakura Fujiwara,Takayasu Moroki,Masaya Hitomi et al.
Sakura Fujiwara et al.
The pancreas plays an important role in the homeostasis of zinc (Zn), a nutritionally essential metal. In several previous studies, Zn ions induced inflammatory changes in the exocrine pancreas; however, little is known about Zn complexes. ...
Satoshi Furukawa,Naho Tsuji,Seigo Hayashi et al.
Satoshi Furukawa et al.
We examined the morphological effects of cyclophosphamide (CPA) on placental development in pregnant rats. CPA was administered as a single dose to pregnant rats intraperitoneally at 0 mg/kg (the control group), 25 mg/kg on gestation day (G...
Pretreatment with tadalafil attenuates cardiotoxicity induced by combretastatin A4 disodium phosphate in rats [0.03%]
他达拉菲预处理减轻朴金果素A4钠磷盐致大鼠心毒性
Yoshiyasu Nagashima,Ryota Tochinai,Shin-Ichi Sekizawa et al.
Yoshiyasu Nagashima et al.
Combretastatin A4 disodium phosphate (CA4DP) is a prodrug of combretastatin A4 (CA4), a microtubule-disassembling agent that exhibits antitumor effects by inhibiting tumor cell proliferation and inducing morphological changes and apoptosis ...