Not so clear on oxygen. Comment on Structural basis for cofactor-independent dioxygenation in vancomycin biosynthesis by Widboom et al. (2007), Nature (London), 447, 342-345 [0.03%]
有关万古霉素生物合成中的Widboom等人的“无辅因子依赖的氧气活化”的结构基础论文的述评
Boguslaw Stec,Kimberly A Stieglitz
Boguslaw Stec
Pseudo-merohedral twinning in crystals of the dihaem c-type cytochrome DHC2 from Geobacter sulfurreducens [0.03%]
Geobacter硫磺还原菌二血红素c型细胞色素DHC2的晶体的伪类子孪生现象研究
Daniel Heitmann,Oliver Einsle
Daniel Heitmann
The dihaem cytochrome DHC2 from Geobacter sulfurreducens has been described as a model system for the study of one of the conserved haem-packing motifs typically observed in multihaem cytochromes c, in which the covalent attachment of haem ...
Structures of viscotoxins A1 and B2 from European mistletoe solved using native data alone [0.03%]
仅利用天然数据解析欧洲槲寄生糖毒蛋白A1和B2的结构
Aritra Pal,Judit E Debreczeni,Madhumati Sevvana et al.
Aritra Pal et al.
Crystals of the cytotoxic thionin proteins viscotoxins A1 and B2 extracted from mistletoe diffracted to high resolution (1.25 and 1.05 A, respectively) and are excellent candidates for testing crystallographic methods. Ab initio direct meth...
Structural analysis of a holoenzyme complex of mouse dihydrofolate reductase with NADPH and a ternary complex with the potent and selective inhibitor 2,4-diamino-6-(2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine [0.03%]
包含NADPH的鼠源二氢叶酸还原酶全酶复合物及其与高效选择性抑制剂2,4-二氨基-6-[2'-羟基二苯并[a,e]庚氮杂色满-5-亚基]甲基喋呤的三联复合物的结构分析
Vivian Cody,Jim Pace,Andre Rosowsky
Vivian Cody
It has been shown that 2,4-diamino-6-arylmethylpteridines and 2,4-diamino-5-arylmethylpyrimidines containing an O-carboxylalkyloxy group in the aryl moiety are potent and selective inhibitors of the dihydrofolate reductase (DHFR) from oppor...
Evaluation of the (haem)Fe--Nepsilon(2)(HisF8) bond distances from haemoglobin structures deposited in the Protein Data Bank [0.03%]
基于蛋白质数据库中的血红蛋白结构对(HAEM)FE-Nε2(HISF8)键距进行评估
Flavio Augusto Vicente Seixas,Talita Dala Santini,Vanessa Pereira de Moura et al.
Flavio Augusto Vicente Seixas et al.
Scientists working on the structure and function of proteins use haemoglobin as a model of allosteric proteins. In this molecule, the (haem)Fe-N(2)(His) bond is one of the most significant because the length of this bond provides relevant i...
The 1.5 A structure of endo-1,3-beta-glucanase from Streptomyces sioyaensis: evolution of the active-site structure for 1,3-beta-glucan-binding specificity and hydrolysis [0.03%]
链霉菌内切-1,3-β-D-葡聚糖酶的1.5a结构：具有1,3-β-d-葡聚糖结合特异性和水解活性的活性位点结构进化
Tang Yao Hong,Yu Yuan Hsiao,Menghsiao Meng et al.
Tang Yao Hong et al.
The catalytic domain structure of Streptomyces sioyaensis 1,3-beta-glucanase (278 amino acids), a member of glycosyl hydrolase family 16 (GHF16), was determined to 1.5 A resolution in space group P2(1)2(1)2(1). The enzyme specifically hydro...
High-molecular-weight polymers for protein crystallization: poly-gamma-glutamic acid-based precipitants [0.03%]
高分子量聚合物在蛋白质结晶中的应用：聚谷氨酸盐类沉淀剂
Ting Chou Hu,Justyna Korczyńska,David K Smith et al.
Ting Chou Hu et al.
Protein crystallization has been revolutionized by the introduction of high-throughput technologies, which have led to a speeding up of the process while simultaneously reducing the amount of protein sample necessary. Nonetheless, the chemi...
Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis [0.03%]
来源于结核分支杆菌的精氨酸阻遏蛋白C端结构
Leonid T Cherney,Maia M Cherney,Craig R Garen et al.
Leonid T Cherney et al.
The Mycobacterium tuberculosis (Mtb) gene product encoded by open reading frame Rv1657 is an arginine repressor (ArgR). All genes involved in the L-arginine (hereafter arginine) biosynthetic pathway are essential for optimal growth of the M...
Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening [0.03%]
单聚体、二聚体和三聚体PCNA结构：PCNA环的组装与开启
Vladena Hlinkova,Guangxin Xing,Jacob Bauer et al.
Vladena Hlinkova et al.
DNA sliding clamps form an oligomeric ring encircling DNA and serve as a moving platform for DNA-processing proteins. The opening and closing of a sliding-clamp ring is essential to load the clamp onto DNA in order to perform its functions....
Elena J Levin,Nathaniel L Elsen,Kory D Seder et al.
Elena J Levin et al.
The 2.07 A resolution X-ray crystal structure of a soluble Rieske-type ferredoxin from Mus musculus encoded by the gene Mm.266515 is reported. Although they are present as covalent domains in eukaryotic membrane oxidase complexes, soluble R...