Keith Tully,Yan Li,Vadim Y Bolshakov
Keith Tully
Glutamatergic projections from the parabrachial nucleus to the central amygdala are implicated in pain transmission. In this issue of Neuron, Delaney et al. identify a new form of adrenergic modulation at these synapses, demonstrating that ...
Robert Shapley
Robert Shapley
Roelfsema, Tolboom, and Khayat have found that neurons in primary visual cortex, V1, increase their spike firing rates to signal image segmentation and attention. V1 responses were in a temporal sequence: first to image motion, next to segm...
Long-term speeding in perceptual switches mediated by attention-dependent plasticity in cortical visual processing [0.03%]
注意依赖的皮层视觉处理的可塑性介导的感知转换的长期加速作用
Satoru Suzuki,Marcia Grabowecky
Satoru Suzuki
Binocular rivalry has been extensively studied to understand the mechanisms that control switches in visual awareness and much has been revealed about the contributions of stimulus and cognitive factors. Because visual processes are fundame...
Selective amplification of stimulus differences during categorical processing of speech [0.03%]
语音范畴加工中选择性放大刺激差异的现象研究
Rajeev D S Raizada,Russell A Poldrack
Rajeev D S Raizada
The brain's perceptual stimuli are constantly changing: some of these changes are treated as invariances and are suppressed, whereas others are selectively amplified, giving emphasis to the distinctions that matter most. The starkest form o...
Motor cortex gates vibrissal responses in a thalamocortical projection pathway [0.03%]
motor皮层控制振动感受信息在丘脑-皮层投射通路中的传递
Nadia Urbain,Martin Deschênes
Nadia Urbain
Higher-order thalamic nuclei receive input from both the cerebral cortex and prethalamic sensory pathways. However, at rest these nuclei appear silent due to inhibitory input from extrathalamic regions, and it has therefore remained unclear...
Anita A Disney,Chiye Aoki,Michael J Hawken
Anita A Disney
Acetylcholine is a ubiquitous cortical neuromodulator implicated in cognition. In order to understand the potential for acetylcholine to play a role in visual attention, we studied nicotinic acetylcholine receptor (nAChR) localization and f...
Bence P Olveczky,Stephen A Baccus,Markus Meister
Bence P Olveczky
Due to fixational eye movements, the image on the retina is always in motion, even when one views a stationary scene. When an object moves within the scene, the corresponding patch of retina experiences a different motion trajectory than th...
Yafell Serulle,Shuang Zhang,Ipe Ninan et al.
Yafell Serulle et al.
Trafficking of AMPA receptors (AMPARs) is regulated by specific interactions of the subunit intracellular C-terminal domains (CTDs) with other proteins, but the mechanisms involved in this process are still unclear. We have found that the G...
PKA activation bypasses the requirement for UNC-31 in the docking of dense core vesicles from C. elegans neurons [0.03%]
活化的蛋白激酶A能够绕过叉丝虫神经元来源的致密核心囊泡对接过程中对UNC-31的要求
Ke-Ming Zhou,Yong-Ming Dong,Qian Ge et al.
Ke-Ming Zhou et al.
The nematode C. elegans provides a powerful model system for exploring the molecular basis of synaptogenesis and neurotransmission. However, the lack of direct functional assays of release processes has largely prevented an in depth underst...
Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines [0.03%]
Kalirin-7控制树突棘结构和功能的活动依赖性可塑性
Zhong Xie,Deepak P Srivastava,Huzefa Photowala et al.
Zhong Xie et al.
Activity-dependent rapid structural and functional modifications of central excitatory synapses contribute to synapse maturation, experience-dependent plasticity, and learning and memory and are associated with neurodevelopmental and psychi...