Moses V Chao
Moses V Chao
Yadin Dudai
Yadin Dudai
Self responses along cingulate cortex reveal quantitative neural phenotype for high-functioning autism [0.03%]
扣带回区域的功能连接可以作为自闭症谱系障碍的神经标志物
Pearl H Chiu,M Amin Kayali,Kenneth T Kishida et al.
Pearl H Chiu et al.
Attributing behavioral outcomes correctly to oneself or to other agents is essential for all productive social exchange. We approach this issue in high-functioning males with autism spectrum disorder (ASD) using two separate fMRI paradigms....
Enhanced intersubject correlations during movie viewing correlate with successful episodic encoding [0.03%]
看电影时增强的组间相关性有助于成功的情节编码
Uri Hasson,Orit Furman,Dav Clark et al.
Uri Hasson et al.
While much has been learned regarding the neural substrates supporting episodic encoding using highly controlled experimental protocols, relatively little is known regarding the neural bases of episodic encoding of real-world events. In an ...
Wu Li,Valentin Piëch,Charles D Gilbert
Wu Li
In complex visual scenes, linking related contour elements is important for object recognition. This process, thought to be stimulus driven and hard wired, has substrates in primary visual cortex (V1). Here, however, we find contour integra...
Cocaine seeking habits depend upon dopamine-dependent serial connectivity linking the ventral with the dorsal striatum [0.03%]
海洛因寻求的习惯依赖于多巴胺调控的伏隔核和纹状体连接机制
David Belin,Barry J Everitt
David Belin
A neuroanatomical principle of striatal organization has been established through which ventral domains, including the nucleus accumbens, exert control over dorsal striatal processes mediated by so-called "spiraling," striato-nigro-striatal...
Active dendritic conductances dynamically regulate GABA release from thalamic interneurons [0.03%]
活跃的树突传导动态调节丘脑间神经元的GABA释放
Claudio Acuna-Goycolea,Stephan D Brenowitz,Wade G Regehr
Claudio Acuna-Goycolea
Inhibitory interneurons in the dorsal lateral geniculate nucleus (dLGN) process visual information by precisely controlling spike timing and by refining the receptive fields of thalamocortical (TC) neurons. Previous studies indicate that dL...
Two Ca(2+)-dependent steps controlling synaptic vesicle fusion and replenishment at the cerebellar basket cell terminal [0.03%]
控制小脑篮细胞末端突触囊泡融合和补充的两个Ca(2+)依赖步骤
Takeshi Sakaba
Takeshi Sakaba
Cerebellar basket cells inhibit postsynaptic Purkinje cells in a rapid and precise manner. To investigate the mechanisms of transmitter release underlying this rapid inhibition, Ca(2+) uncaging was employed to measure the intracellular Ca(2...
Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice [0.03%]
敲除未折叠蛋白反应介导物CHOP可恢复Charcot-Marie-Tooth 1B型小鼠的运动功能并减少脱髓鞘现象
Maria Pennuto,Elisa Tinelli,Mariachiara Malaguti et al.
Maria Pennuto et al.
Deletion of serine 63 from P0 glycoprotein (P0S63del) causes Charcot-Marie-Tooth 1B neuropathy in humans, and P0S63del produces a similar demyelinating neuropathy in transgenic mice. P0S63del is retained in the endoplasmic reticulum and fai...
Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex [0.03%]
Satb2是新皮层上层神经元规范的(postmitotic)决定因子
Olga Britanova,Camino de Juan Romero,Amanda Cheung et al.
Olga Britanova et al.
Pyramidal neurons of the neocortex can be subdivided into two major groups: deep- (DL) and upper-layer (UL) neurons. Here we report that the expression of the AT-rich DNA-binding protein Satb2 defines two subclasses of UL neurons: UL1 (Satb...