Hyper-Aggressiveness of Bystander Cells in an Anti-Tumor Photodynamic Therapy Model: Role of Nitric Oxide Produced by Targeted Cells [0.03%]
光动力治疗模型中旁观者细胞的超攻击性：靶向细胞产生的一氧化氮的作用
Jerzy Bazak,Witold Korytowski,Albert W Girotti
Jerzy Bazak
When selected tumor cells in a large in vitro population are exposed to ionizing radiation, they can send pro-survival signals to non-exposed counterparts (bystander cells). If there is no physical contact between irradiated and bystander c...
Historical Perspectives of the Role of NO/NO Donors in Anti-Tumor Activities: Acknowledging Dr. Keefer's Pioneering Research [0.03%]
一氧化氮供体的抗肿瘤活性作用的历史视角：肯定Keefer博士的开拓性研究
Benjamin Bonavida
Benjamin Bonavida
The role of nitric oxide (NO) in cancer has been a continuous challenge and particularly the contradictory findings in the literature reporting NO with either anti-cancer properties or pro-cancer properties. This dilemma was largely resolve...
Khosrow Kashfi
Khosrow Kashfi
Eliminating Cancer Stem-Like Cells in Oral Cancer by Targeting Elementary Signaling Pathways [0.03%]
通过靶向基本信号通路消除口腔癌干细胞样细胞
Jigna Joshi,Hitarth Patel,Hunayna Bhavnagari et al.
Jigna Joshi et al.
Oral cancer is a heterogeneous, aggressive, and complex entity. Current major treatment options for the disease are surgery, chemo, and/or radiotherapy either alone or in combination with each other. Each treatment method has its own limita...
Role of the Tumor Microenvironment and the Influence of Epigenetics on the Tumor Microenvironment in Oral Carcinogenesis: Potential Implications [0.03%]
肿瘤微环境的作用以及表观遗传学对口腔上皮恶性转化过程中肿瘤微环境的影响：潜在意义
Sagar Dholariya,Ragini D Singh,Madhuri Radadiya et al.
Sagar Dholariya et al.
Oral cancer has become a significant problem throughout the world, particularly in countries that are still developing. Recent literature supports the contribution of components of the tumor microenvironment (TME) and the effect of epigenet...
Daksh Goel,Siddharth Shah,Manish Mair
Daksh Goel
Oral cancer is a major health concern in developing countries like India which contributes one-third of the global oral cancer burden. Unlike other non-head and neck malignancies, oral cancer has a more curative treatment course. If detecte...
Siddhartha Dutta,Shubha Singhal,Rima B Shah et al.
Siddhartha Dutta et al.
Oral cancers (OCs), being one of the frequent malignancies in the head and neck region, need prompt diagnosis and treatment. Apart from basic therapeutic modalities, immunotherapy has now been utilized as a novel approach to combat the dise...
CRISPR/Cas9: A Molecular Tool for Ovarian Cancer Management beyond Gene Editing [0.03%]
CRISPR/Cas9：超越基因编辑的卵巢癌管理分子工具
Sagar Dholariya,Deepak Parchwani,Madhuri Radadiya et al.
Sagar Dholariya et al.
Ovarian cancer manifests with early metastases and has an adverse outcome, impacting the health of women globally. Currently, this malignancy is often treated with cytoreductive surgery and platinum-based chemotherapy. This treatment option...