Brayden K Leyva,Benjamin Bonavida
Brayden K Leyva
The interplay between probiotics and cancer development has emerged as a complex but important field in oncology research. While probiotics are known gut microbiome modulators and have the ability to modulate an immune response, their role ...
Review Article: Probiotics-Mediated Enhancement of Checkpoint Inhibitor Blockade for HER2+ Breast Cancer [0.03%]
综述文章： probiotics介导的免疫检验点抑制剂阻断在HER2阳性乳腺癌中的应用增强效应
Mai Ho,Benjamin Bonavida
Mai Ho
Immune checkpoint inhibitors (ICIs) have significantly improved survival rates for many types of cancer, giving patients survival prognoses that had been previously unattainable. Unfortunately, in many advanced cancers, including breast can...
Review Article: Fecal Microbiota Transplantation in Melanoma: Mechanisms-Mediated Enhancement of Anti-Tumor Immunotherapy [0.03%]
综述文章：粪便微生物群移植在黑色素瘤中的应用：增强抗肿瘤免疫治疗的机制
William Ung,Benjamin Bonavida
William Ung
The gut microbiota is integral to human health, influencing nutrition, metabolism, and immunity. Dysbiosis has been implicated in cancer development and resistance to therapies, highlighting the potential of microbiota modulation as a thera...
Review Article: Involvement of the Gut Microbiome and Probiotic Interventions in Pediatric Acute Lymphoblastic Leukemia [0.03%]
综述文章：肠道菌群与益生菌干预在儿童急性淋巴细胞白血病中的作用
Inesa Navasardyan
Inesa Navasardyan
Acute lymphoblastic leukemia (ALL) is a common pediatric cancer marked by uncontrolled proliferation of lymphoblasts, primarily affecting children aged two to five years. While treatment success rates have reached 90% in children, challenge...
Review Article: Understanding the Role of the Microbiome in Breast Cancer Progression [0.03%]
综述文章：理解微生物组在乳腺癌进展中的作用
Seema Kumari,Mundla Srilatha,Ganji Purnachndra Nagaraju
Seema Kumari
The breast cancer fatality rate poses a global health concern. Dysbiosis of the gut and breast microbiome plays a crucial role in both the onset and metastasis of breast cancer by influencing immune response and hormone metabolism. Probioti...
Benjamin Bonavida,Luca Falzone,Massimo Libra
Benjamin Bonavida
In Silico Analysis of Anti-Cancer Activity of Exopolysaccharide Isolated from Novel Pseudolagarobasidium acaciicola through Mass Production, Gel Permeation Separation, and Compositional Analysis [0.03%]
通过高效生产、凝胶渗透分离及组分分析对一株新型黏帚霉(Pseudolagarobasidium acaciicola)多糖抗肿瘤活性的模拟分析
Smita Behera,Nibha Gupta
Smita Behera
Bacteria, fungi, and algae are examples of microorganisms that synthesize polysaccharides, which are macromolecules that belong to the carbohydrate class. Production of polysaccharides represents an alternative to chemical and plant-derived...
Targeting Breast Adenocarcinoma with Grangea maderaspatana Natural Compounds: A Molecular Docking and Pharmacokinetic Study [0.03%]
基于分子对接和药代动力学的格兰吉娅天然产物抗乳腺腺癌研究
Suraj Rajakumari,Pavithra Uppathi,Kallimakula Venkareddy Saritha
Suraj Rajakumari
Millions of women worldwide have breast cancer, a common and possibly fatal illness according to WHO Reports. A genetic mutation usually causes breast adenocarcinomas. Only 5-10% of cancers are induced by genetic mutations that develop with...
Molecular Dynamics of Adenomatous Polyposis Coli (APC) Protein and Its Inhibitors: A Special Insight to Colorectal Cancer [0.03%]
腺瘤性结直肠癌蛋白和其抑制剂的分子动力学研究：一种关于结直肠癌的独特见解
Rina Kumari,Dilip Ghava,Rajeshwari Rathod et al.
Rina Kumari et al.
Colorectal cancer (CRC) initiates in colon or rectum is named as colon or rectal cancer, based on the site of inception. Various genetic alterations responsible for CRC include several signaling pathways. The Wingless/Wnt signaling pathway ...
Coralyne Targets the Catalytic Domain of MMP9: An In Silico and In Vitro Investigation [0.03%]
Coralyne靶向MMP9的催化结构域：一种基于计算机和体外的研究
Rahul Kumar Vempati,Rama Rao Malla
Rahul Kumar Vempati
Coralyne (COR) is a protoberberine-like isoquinoline alkaloid, and it is known for double-stranded (ds) DNA intercalation and topoisomerase inhibition. It can also sensitize cancer cells through various mechanisms. COR reduces the prolifera...