The frequency of C4B variants of complement in familial and sporadic Alzheimer disease [0.03%]
补体C4B变异体在家族性和散发性阿尔茨海默病中的发生频率
T D Bird,M Boehnke,J Anderson et al.
T D Bird et al.
A previous study reported an unexpected increased frequency of the uncommon C4B2 allele of complement in a group of patients with senile dementia of the Alzheimer type. We compared the frequency of various C4B types in 25 patients with fami...
Neuronal degeneration in locus ceruleus and cortical correlates of Alzheimer disease [0.03%]
蓝斑神经元退变及阿尔茨海默病的皮层相关病变
W Bondareff,C Q Mountjoy,M Roth et al.
W Bondareff et al.
Relationships were examined between neuronal degeneration in the nucleus locus ceruleus (nLC), a parameter of central noradrenergic impairment, and neocortical markers of Alzheimer disease (AD). The loss of nLC neurons was found to correlat...
Correlations between histopathologic white matter changes and proton MR relaxation times in dementia [0.03%]
痴呆小鼠脑白质变化与氢MR弛豫时间的相关性研究
E Englund,A Brun,B Persson
E Englund
Our previous studies have shown that incomplete white matter infarctions are common in senile dementia of the Alzheimer type. To visualize and interpret these changes on magnetic resonance imaging (MRI), knowledge of MR relaxation times ass...
L F Jarvik
L F Jarvik
Relatives' descriptions of changes in symptoms of dementia of the Alzheimer type: a comparison of retrospective and concurrent ratings [0.03%]
阿尔茨海默型痴呆症状变化的亲属描述：回顾性和同时性评定结果的比较
J S Watson,S S Matsuyama,P M Dirham et al.
J S Watson et al.
Although relatives' retrospective reports are often used in characterizing the onset and progression of symptoms in dementia of the Alzheimer type (DAT), little is known about the accuracy of these accounts. The primary purpose of this pape...
Platelet membrane properties in Alzheimer and multi-infarct dementias [0.03%]
阿尔茨海默型和多梗死型痴呆的血小板膜性质研究
N Hicks,M J Brammer,N Hymas et al.
N Hicks et al.
Recent investigations revealed that the physical properties of both central and peripheral cell membranes are changed in dementia of the Alzheimer Type (DAT). We attempted to ascertain whether this effect is specific for DAT by studying the...
Effect of dietary silicon and aluminum on silicon and aluminum levels in rat brain [0.03%]
饮食硅和铝对大鼠脑内硅和铝水平影响的实验研究
E M Carlisle,M J Curran
E M Carlisle
This preliminary study was undertaken to investigate the effect of dietary silicon and aluminum on levels of these elements in brain. Two ages of rats, 22 day and 10 month, were assigned to 1 of 4 diets: 1) low silicon; 2) low silicon plus ...
A J Tobin
A J Tobin
A B Scheibel,T H Duong,U Tomiyasu
A B Scheibel
Structural analysis of the capillary plexus in the brains of 5 patients with clinical and neuropathological diagnosis of Senile Dementia, Alzheimer Type, revealed a group of striking physical alterations compared with tissue specimens from ...