Health behavior changes after genetic risk assessment for Alzheimer disease: The REVEAL Study [0.03%]
遗传风险评估对阿尔茨海默病的健康行为改变：REVEAL研究
Serena Chao,J Scott Roberts,Theresa M Marteau et al.
Serena Chao et al.
Risk information for Alzheimer disease (AD) may be communicated through susceptibility gene disclosure, even though this is not currently in clinical use. The REVEAL Study is the first randomized clinical trial of risk assessment for AD wit...
Randomized Controlled Trial
Alzheimer disease and associated disorders. 2008 Jan-Mar;22(1):94-7. DOI:10.1097/WAD.0b013e31815a9dcc 2008
Jiska Cohen-Mansfield
Jiska Cohen-Mansfield
Persons with dementia have difficulty communicating, which has led to the underdetection and undertreatment of pain in this population. In this paper, we compare pain assessments using 3 different measurement types: self-report, informant r...
The Public's ability to recognize Alzheimer disease and their beliefs about its causes [0.03%]
公众对阿尔茨海默病的认识及其对病因的信念
Sergio Luís Blay,Erica de Toledo Piza Peluso
Sergio Luís Blay
The authors report how the population identifies symptoms of Alzheimer disease (AD) and the causes attributed to this disorder in the city of São Paulo, Brazil. A total of 500 household residents aged 18 years and above were examined in a ...
Applicability of the abbreviated neuropsychologic battery (NEUROPSI) in Alzheimer disease patients [0.03%]
阿尔茨海默病患者的简明神经心理学测验(NEUROPSI)的应用性研究
Jacqueline Abrisqueta-Gomez,Feggy Ostrosky-Solis,Paulo H F Bertolucci et al.
Jacqueline Abrisqueta-Gomez et al.
NEUROPSI is a brief neuropsychologic battery developed to briefly assess a wide spectrum of cognitive functions. The aim of this study was to examine the applicability of a Portuguese version of this battery and verify the efficacy in detec...
Nutritional status is associated with disease progression in very mild Alzheimer disease [0.03%]
营养状况与非常轻微阿尔茨海默病的疾病进展相关
Pierre-Jean Ousset,Fati Nourhashemi,Emma Reynish et al.
Pierre-Jean Ousset et al.
The objective of this study is to identify, in a sample of very mild Alzheimer disease (AD) patients, factors associated with disease progression. The authors followed 160 AD patients from a multicenter cohort with a Clinical Dementia Ratin...
Polymorphisms of APOE and LRP genes in Brazilian individuals with Alzheimer disease [0.03%]
apoE和LRP基因多态性在巴西阿尔茨海默病患者中的分布研究
Valéria Santoro Bahia,Fernando Kok,Suely Nagahashi Marie et al.
Valéria Santoro Bahia et al.
Alzheimer disease (AD) is the most frequent cause of dementia in Western countries. Putative genetic risk factors for AD are polymorphisms in the apolipoprotein E (APOE) gene and in the low-density lipoprotein receptor-related protein (LRP)...
Brain N-acetylaspartate is reduced in Parkinson disease with dementia [0.03%]
帕金森病伴痴呆患者脑内N-乙酰天门冬氨酸减少
Henry Randall Griffith,Jan A den Hollander,Ozioma C Okonkwo et al.
Henry Randall Griffith et al.
Persons with Parkinson disease (PD) are at risk of developing dementia. Of the dementias affecting patients with PD, PD with dementia (PDD) is not well understood, although brain imaging studies to date have observed characteristic patterns...
Diagnostic value of CSF biomarker profile in frontotemporal lobar degeneration [0.03%]
额颞叶变性脑脊液生物标志检测的诊断价值分析
Elisabeth Kapaki,George P Paraskevas,Sokratis G Papageorgiou et al.
Elisabeth Kapaki et al.
Background: Cerebrospinal fluid (CSF) biomarkers have been increasingly studied in dementia clinical and differential diagnosis. Methods: ...
Cardiorespiratory fitness in early-stage Alzheimer disease [0.03%]
阿尔茨海默病早期患者的 cardiorespiratory fitness
Jeffrey M Burns,Matthew S Mayo,Heather S Anderson et al.
Jeffrey M Burns et al.
There is an increasing interest in exercise and fitness in Alzheimer disease (AD) given evidence suggesting a role in the maintenance of cognitive health. There is, however, little data on the objective measure of cardiorespiratory fitness ...
Effects of galantamine on measures of attention: results from 2 clinical trials in Alzheimer disease patients with comparisons to donepezil [0.03%]
石杉碱甲对注意力指标的影响：来自阿尔茨海默病患者的2项临床试验结果及与多奈哌齐的对比研究
James E Galvin,Barbara Cornblatt,Paul Newhouse et al.
James E Galvin et al.
Deficits in attention are present early in the course of Alzheimer disease (AD). Acetylcholine receptors are appealing molecular targets for intervention as cholinergic pathways are involved in the neurobiology of attention. For this reason...
Randomized Controlled Trial
Alzheimer disease and associated disorders. 2008 Jan-Mar;22(1):30-8. DOI:10.1097/WAD.0b013e3181630b81 2008