Cerebrospinal fluid of patients with senile dementia of Alzheimer's type shows an increased inhibition of alpha-chymotrypsin [0.03%]
阿尔茨海默型老年性痴呆病人脑脊液对α-糜蛋白酶有抑制作用
F Licastro,L J Davis,M C Morini et al.
F Licastro et al.
The inhibition of alpha-chymotrypsin induced by cerebrospinal fluid from patients with senile dementia of Alzheimer's type, vascular dementia, and nondemented controls was investigated. We optimized the sensitivity of the assay so that the ...
G W Rebok,P M Keyl,F W Bylsma et al.
G W Rebok et al.
Ten Alzheimer disease (AD) patients and 12 healthy elderly controls were evaluated on two tests of driving-related abilities: the Driver Performance Test (DPT) and the Driving Advisement System (DAS). Subjects were administered a battery of...
Neurofibrillary pathology in brains of elderly schizophrenics treated with neuroleptics [0.03%]
抗精神病药物对老年精神分裂症患者脑神经原纤维病変的影响
H M Wisniewski,J Constantinidis,J Wegiel et al.
H M Wisniewski et al.
The clinical histories of 102 schizophrenics who died at 70 years of age or older were reviewed. The incidence of neurofibrillary tangles (NFTs) was two times higher in the patients who received (74%) than in those who did not receive (36%)...
Guidelines for addressing ethical and legal issues in Alzheimer disease research: a position paper. National Institute on Aging [0.03%]
阿尔茨海默病研究中的伦理和法律问题处理指南：立场文件。国家老龄化研究所
D M High,P J Whitehouse,S G Post et al.
D M High et al.
Determining the competency of Alzheimer patients to consent to treatment and research [0.03%]
确定阿尔茨海默氏症患者同意治疗和研究的能力
D C Marson,F A Schmitt,K K Ingram et al.
D C Marson et al.
Loss of competency is an inevitable consequence of Alzheimer disease (AD) and other progressive dementias. Of particular importance to clinicians and researchers studying dementia is determining whether a patient has the capacity to provide...
D M High,S G Post,P J Whitehouse
D M High
The temporal-distance effect in subjects with dementia of the Alzheimer type [0.03%]
阿尔茨海默病患者中的时间-距离效应
J Madsen,R P Kesner
J Madsen
The efficacy of temporal-distance processing for spatial locations was evaluated in college students, elderly controls, and subjects with mild and moderate dementia of the Alzheimer type (DAT). The elderly controls showed a slightly lower l...
J L Cummings,W Ross,J Absher et al.
J L Cummings et al.
Depression is difficult to assess in Alzheimer disease (AD) and controversy surrounds the prevalence, etiology, and characteristics of mood alterations in patients with this disorder. We used a variety of standardized instruments to assess ...
Family burden in the care of the demented and nondemented elderly--a longitudinal study [0.03%]
纵向研究：照料痴呆和非痴呆老年人的家庭负担
M Grafström,B Winblad
M Grafström
This study describes how the situation will change with time when a close relative cares for a demented or nondemented elderly. The changes over a period of time in cognitive and behavioral deterioration, perceived burden, and social suppor...
Alterations in metabolic properties in fibroblasts in Alzheimer disease [0.03%]
阿尔茨海默病患者成纤维细胞代谢特性的改变
S Sorbi,S Piacentini,S Latorraca et al.
S Sorbi et al.
Alzheimer disease (AD) leads to alterations in several biochemical properties in cultured skin fibroblasts. Because abnormal glucose metabolism has been reported in both in vivo and in vitro studies of the brain, we examined glucose and glu...