L Gwyther
L Gwyther
M B Patterson,P J Whitehouse
M B Patterson
C Randolph,J W Roberts,M C Tierney et al.
C Randolph et al.
Degeneration of cortical glutamatergic projections may contribute to the cognitive decline in Alzheimer disease (AD). To evaluate whether 1glutamate system stimulation might confer symptomatic benefit, we administered D-cycloserine, a putat...
Ceruloplasmin is increased in cerebrospinal fluid in Alzheimer's disease but not Parkinson's disease [0.03%]
ceruloplasmin在阿尔茨海默病但不是帕金森病患者的脑脊液中升高
D A Loeffler,A J DeMaggio,P L Juneau et al.
D A Loeffler et al.
Although the pathophysiology of Alzheimer's disease (AD) and Parkinson's disease (PD) is unknown, altered brain antioxidative mechanisms have been found in both disorders. Ceruloplasmin (CP) and transferrin (TF) interact to limit concentrat...
J Horner,M J Alberts,D V Dawson et al.
J Horner et al.
Using a prospective case series design, we examined the incidence of oropharyngeal swallowing abnormalities in 25 patients with moderate or severe Alzheimer's disease by videofluoroscopy. Aspiration occurred in 6 of 25 (28.6%). Only four pa...
Primary caregivers' descriptions of Alzheimer patients' personality traits: temporal stability and sensitivity to change [0.03%]
照料者的认知：阿尔茨海默病患者的个性特征的稳定性及敏感性描述
M E Strauss,M Pasupathi
M E Strauss
Caregivers of Alzheimer's disease patients provided characterizations of the patients' premorbid personality traits and current personality traits on two occasions nearly 1 year apart. Characterizations of pre-illness personality traits did...
New opportunities in AD research--roles of immunoinflammatory responses and glia [0.03%]
阿尔茨海默病研究中的新机遇——免疫炎症反应和胶质细胞的作用
R D Frederickson,K K Brunden
R D Frederickson
P L McGeer,J Rogers,E G McGeer
P L McGeer
Lesions in Alzheimer disease are characterized by the assembly of a variety of cells and proteins associated with the immune system. Activated microglia express high levels of major histocompatibility complex glycoproteins and receptors for...
Prolonged latencies of pattern reversal visual evoked early potentials in Alzheimer disease [0.03%]
阿尔茨海默病患者反转视觉诱发电位早期成分潜伏期延长
J Partanen,P Hartikainen,M Könönen et al.
J Partanen et al.
We studied patients with Alzheimer disease, Parkinson disease, and amyotrophic lateral sclerosis (ALS) with a pattern reversal (checkerboard light diode) visual evoked potential (VEP) paradigm to observe the involvement of the visual system...