Topographic patterns of brain functional impairment progression according to clinical severity staging in 116 Alzheimer disease patients: FDG-PET study [0.03%]
阿尔茨海默病患者临床严重程度分期的脑功能障碍进展模式：基于116例患者的氟脱氧葡萄糖正电子发射断层显像研究
Il Han Choo,Dong Young Lee,Jong Choul Youn et al.
Il Han Choo et al.
The study aimed to explore topographic progression pattern of brain functional impairment according to clinical stage in Alzheimer disease (AD). One hundred and sixteen AD patients and 25 normal subjects underwent a [18F] fluorodeoxyglucose...
Category fluency as a screening test for Alzheimer disease in illiterate and literate patients [0.03%]
文盲和识字患者中类别流畅性作为阿尔茨海默病的筛查试验
Paulo Caramelli,Maria Teresa Carthery-Goulart,Cláudia Sellitto Porto et al.
Paulo Caramelli et al.
Brief cognitive tests are widely used for dementia screening, but are usually influenced by education. The present work aimed to determine education-adjusted cut-off scores and correspondent sensitivity (S) and specificity (Sp) values of th...
Controlled Clinical Trial
Alzheimer disease and associated disorders. 2007 Jan-Mar;21(1):65-7. DOI:10.1097/WAD.0b013e31802f244f 2007
Memantine treatment of cognitive symptoms in mild to moderate Alzheimer disease: secondary analyses from a placebo-controlled randomized trial [0.03%]
memantine治疗轻至中度阿尔茨海默病认知症状的次要分析：一项安慰剂对照随机试验
Nunzio Pomara,Brian R Ott,Elaine Peskind et al.
Nunzio Pomara et al.
Memantine, an N-methyl-D-aspartate receptor antagonist, is approved in the United States and Europe for the treatment of moderate to severe Alzheimer disease (AD) and has also been investigated in patients with mild to moderate AD. To chara...
Randomized Controlled Trial
Alzheimer disease and associated disorders. 2007 Jan-Mar;21(1):60-4. DOI:10.1097/WAD.0b013e318032cf29 2007
Kurt Segers
Kurt Segers
Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the way in which dementia patients and their medical care are described in films. T...
Decision making on behalf of elders with advanced cognitive impairment: family transitions [0.03%]
家属代理决策：认知能力衰退老人的决策变迁研究
Barbara A Elliott,Charles E Gessert,Cynthia Peden-McAlpine
Barbara A Elliott
Changes in family decision making responsibilities occur with progression of cognitive impairment. Focus groups with family members of nursing home residents with advanced cognitive impairment investigated values and beliefs used in making ...
Evaluated need, costs of care, and payer perspective in degenerative dementia patients cared for in the United States [0.03%]
美国退行性痴呆患者的评估需求、护理成本和支付者视角
Daniel L Murman,Alexander Von Eye,Paula R Sherwood et al.
Daniel L Murman et al.
The purpose of this study was to examine the strength of the associations between 5 measures of need that are potentially modifiable in degenerative dementia patients and direct costs of care from 5 payer perspectives in the US healthcare s...
Wandering behavior and Alzheimer disease. The REAL.FR prospective study [0.03%]
徘徊行为和阿尔茨海默病REAL.FR前瞻性研究
Yves Rolland,Sandrine Andrieu,Christelle Cantet et al.
Yves Rolland et al.
We evaluated the predictive value of wandering behavior at baseline for nutritional status, disability, institutionalization, and mortality in 686 Alzheimer disease community-dwelling subjects enrolled in the prospective REAL.FR study, Fran...
Claire-Marie Verdon,Philippe Fossati,Marc Verny et al.
Claire-Marie Verdon et al.
Objective: A core component of social functioning is the capacity to attribute mental states to others and to understand intention as psychologic cause. The hypothesis of this study was that dementia of the Alzheimer type...
Cerebral ventricular changes associated with transitions between normal cognitive function, mild cognitive impairment, and dementia [0.03%]
从正常认知功能到轻度认知障碍再到痴呆的认知过渡过程中脑室变化的特点分析
Owen T Carmichael,Lewis H Kuller,Oscar L Lopez et al.
Owen T Carmichael et al.
Expansion of the cerebral ventricles may occur at an accelerated rate in subjects with dementia, but the time course of expansion during transitions between normal cognitive function, mild cognitive impairment (MCI), and dementia is not wel...
Profiles of decline in activities of daily living in non-Alzheimer dementia [0.03%]
非阿尔茨海默病性痴呆患者日常生活能力下降的轨迹特征分析
Alissa H Wicklund,Nancy Johnson,Alfred Rademaker et al.
Alissa H Wicklund et al.
Assessment of functional ability is an essential component in the clinical diagnosis of dementia. Most studies have primarily focused on disability due to Alzheimer disease (AD), and less is known about profiles of functional impairment in ...